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hsa-miR-99a-5p (MIMAT0000097) (129 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-99a-5p RAVER2
Western blot [1]
Luciferase reporter assay [1]
Immunoprecipitaion [1]
hsa-miR-99a-5p FGFR3
qRT-PCR [2] [3]
Reporter assay [4]
Western blot [2] [4] [3]
Luciferase reporter assay [2] [3]
hsa-miR-99a-5p IGF1R
qRT-PCR [5] [6] [7] [8]
Western blot [6] [7] [8]
Immunoblot [5]
Luciferase reporter assay [5] [6] [7] [8]
hsa-miR-99a-5p MTOR
qRT-PCR [7] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [19]
microarray [14]
ChIP [15]
Reporter assay [4]
Western blot [19] [7] [9] [10] [11] [12] [20] [14] [15] [16] [17] [4] [18]
Immunoblot [13]
Luciferase reporter assay [10] [11] [14] [12] [13] [20] [16] [17] [18] [19] [7] [9]
Immunoprecipitaion [15]
Flow cytometry [15]
Immunohistochemistry [15]
FACS [12] [10]
hsa-miR-99a-5p AGO2
qRT-PCR [21]
Western blot [21]
Luciferase reporter assay [21]
Sequencing [22]
hsa-miR-99a-5p MEF2D
Sequencing [22]
hsa-miR-99a-5p SKI
Sequencing [22]
hsa-miR-99a-5p COQ2
Sequencing [22]
hsa-miR-99a-5p TRIB1
Sequencing [22]
hsa-miR-99a-5p MRPS33
CLASH [23]
hsa-miR-99a-5p CCDC6
CLASH [23]
hsa-miR-99a-5p RASAL2
CLASH [23]
hsa-miR-99a-5p LRIG3
CLASH [23]
hsa-miR-99a-5p DDX18
CLASH [23]
hsa-miR-99a-5p ND3
CLASH [23]
hsa-miR-99a-5p METTL23
CLASH [23]
hsa-miR-99a-5p MAPK6
CLASH [23]
hsa-miR-99a-5p ZNF367
CLASH [23]
hsa-miR-99a-5p APEX1
CLASH [23]
hsa-miR-99a-5p N4BP2
CLASH [23]
hsa-miR-99a-5p RCN2
CLASH [23]
hsa-miR-99a-5p RPL36A
CLASH [23]
hsa-miR-99a-5p GXYLT1
CLASH [23]
hsa-miR-99a-5p DDX3X
CLASH [23]
hsa-miR-99a-5p EIF5A
CLASH [23]
hsa-miR-99a-5p UTP4
CLASH [23]
hsa-miR-99a-5p STEAP4
CLASH [23]
hsa-miR-99a-5p RPS26
CLASH [23]
hsa-miR-99a-5p DLD
CLASH [23]
hsa-miR-99a-5p ORMDL1
CLASH [23]
hsa-miR-99a-5p RARS
CLASH [23]
hsa-miR-99a-5p CUL2
CLASH [23]
hsa-miR-99a-5p FOSL2
CLASH [23]
hsa-miR-99a-5p ADGRG6
CLASH [23]
hsa-miR-99a-5p GNAL
CLASH [23]
hsa-miR-99a-5p MON1B
CLASH [23]
hsa-miR-99a-5p SPIRE1
CLASH [23]
hsa-miR-99a-5p TOMM22
CLASH [23]
hsa-miR-99a-5p ORC5
CLASH [23]
hsa-miR-99a-5p NDE1
CLASH [23]
hsa-miR-99a-5p TNRC6B
CLASH [23]
hsa-miR-99a-5p UBB
CLASH [23]
hsa-miR-99a-5p SRPK1
CLASH [23]
hsa-miR-99a-5p CAPNS1
CLASH [23]
hsa-miR-99a-5p RPS6
CLASH [23]
hsa-miR-99a-5p SNRNP200
CLASH [23]
hsa-miR-99a-5p SRSF10
CLASH [23]
hsa-miR-99a-5p HADHB
CLASH [23]
hsa-miR-99a-5p LMAN2
CLASH [23]
hsa-miR-99a-5p GTF2H1
CLASH [23]
hsa-miR-99a-5p N6AMT1
CLASH [23]
hsa-miR-99a-5p SGPP2
CLASH [23]
hsa-miR-99a-5p GDE1
CLASH [23]
hsa-miR-99a-5p VPS45
CLASH [23]
hsa-miR-99a-5p FAM171B
CLASH [23]
hsa-miR-99a-5p UQCR10
CLASH [23]
hsa-miR-99a-5p PUM1
CLASH [23]
hsa-miR-99a-5p AKAP2
CLASH [23]
hsa-miR-99a-5p EXTL3
CLASH [23]
hsa-miR-99a-5p NFU1
CLASH [23]
hsa-miR-99a-5p UBA2
CLASH [23]
hsa-miR-99a-5p RB1
CLASH [23]
hsa-miR-99a-5p RPL7L1
CLASH [23]
hsa-miR-99a-5p PLSCR1
CLASH [23]
hsa-miR-99a-5p WHAMM
CLASH [23]
hsa-miR-99a-5p ITM2B
CLASH [23]
hsa-miR-99a-5p POGK
CLASH [23]
hsa-miR-99a-5p SEC13
CLASH [23]
hsa-miR-99a-5p TPPP3
CLASH [23]
hsa-miR-99a-5p RPS15
CLASH [23]
hsa-miR-99a-5p GTF2H2C
CLASH [23]
hsa-miR-99a-5p TMEM209
CLASH [23]
hsa-miR-99a-5p SYNJ2BP
CLASH [23]
hsa-miR-99a-5p MED12
CLASH [23]
hsa-miR-99a-5p DOCK11
CLASH [23]
hsa-miR-99a-5p ATP5E
CLASH [23]
hsa-miR-99a-5p DHCR24
CLASH [23]
hsa-miR-99a-5p PPM1A
CLASH [23]
hsa-miR-99a-5p NPM3
CLASH [23]
hsa-miR-99a-5p MYL2
CLASH [23]
hsa-miR-99a-5p CBWD1
CLASH [23]
hsa-miR-99a-5p JPH1
CLASH [23]
hsa-miR-99a-5p GTF2I
CLASH [23]
hsa-miR-99a-5p NDUFA2
CLASH [23]
hsa-miR-99a-5p COL4A1
CLASH [23]
hsa-miR-99a-5p FOXRED2
CLASH [23]
hsa-miR-99a-5p AGO1
CLASH [23]
hsa-miR-99a-5p RUNDC3B
CLASH [23]
hsa-miR-99a-5p COX2
CLASH [23]
hsa-miR-99a-5p TUBG1
CLASH [23]
hsa-miR-99a-5p DDX42
CLASH [23]
hsa-miR-99a-5p ADO
CLASH [23]
hsa-miR-99a-5p ADCY9
CLASH [23]
hsa-miR-99a-5p CTC1
CLASH [23]
hsa-miR-99a-5p MCM8
CLASH [23]
hsa-miR-99a-5p ATP1A1
CLASH [23]
hsa-miR-99a-5p DNAJA3
CLASH [23]
hsa-miR-99a-5p RAD51C
CLASH [23]
hsa-miR-99a-5p DDX46
CLASH [23]
hsa-miR-99a-5p MARK2
CLASH [23]
hsa-miR-99a-5p RPL37A
CLASH [23]
hsa-miR-99a-5p TYMS
CLASH [23]
hsa-miR-99a-5p DDHD1
CLASH [23]
hsa-miR-99a-5p SALL2
CLASH [23]
hsa-miR-99a-5p PSMA2
CLASH [23]
hsa-miR-99a-5p SUDS3
CLASH [23]
hsa-miR-99a-5p P2RY11
CLASH [23]
hsa-miR-99a-5p E4F1
CLASH [23]
hsa-miR-99a-5p NFE2L1
CLASH [23]
hsa-miR-99a-5p GLUD1
CLASH [23]
hsa-miR-99a-5p RNF187
CLASH [23]
hsa-miR-99a-5p CUL3
CLASH [23]
hsa-miR-99a-5p AP2B1
CLASH [23]
hsa-miR-99a-5p GOLGA3
CLASH [23]
hsa-miR-99a-5p ZBTB4
CLASH [23]
hsa-miR-99a-5p BRD7
CLASH [23]
hsa-miR-99a-5p CERS1
CLASH [23]
hsa-miR-99a-5p TTC38
CLASH [23]
hsa-miR-99a-5p MTMR3
qRT-PCR [24]
Western blot [24]
Luciferase reporter assay [24]
hsa-miR-99a-5p SMARCA5
qRT-PCR [14]
microarray [14]
Western blot [14] [25]
Luciferase reporter assay [14]
PAR-CLIP [26] [22] [27]
hsa-miR-99a-5p HOXA1
qRT-PCR [14]
microarray [14]
Western blot [14]
Luciferase reporter assay [14]
hsa-miR-99a-5p KBTBD8
PAR-CLIP [28] [26] [27]
hsa-miR-99a-5p TRIB2
Luciferase reporter assay [29]
hsa-miR-99a-5p FKBP5
qRT-PCR [10]
Western blot [10]
Luciferase reporter assay [10]
FACS [10]
hsa-miR-99a-5p GRHL1
qRT-PCR [30]
microarray [30]
hsa-miR-99a-5p PPP1CB
qRT-PCR [30]
microarray [30]
hsa-miR-99a-5p CTDSPL
Luciferase reporter assay [29]
hsa-miR-99a-5p SMPDL3B
PAR-CLIP [22] [28]
hsa-miR-99a-5p TMEM30A
PAR-CLIP [27]

References

authors journal year Pubmed link title
1 Beitzinger et al. RNA Biol 2007 17637574 Identification of human microRNA targets from isolated argonaute protein complexes.
2 Catto et al. Cancer Res. 2009 19843843 Distinct microRNA alterations characterize high- and low-grade bladder cancer.
3 Jiang et al. Biomed. Pharmacother. 2014 24456664 miR-99a promotes proliferation targeting FGFR3 in human epithelial ovarian cancer cells.
4 Oneyama et al. Oncogene 2011 21383697 MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways.
5 Yen et al. Mol. Cancer 2014 24410957 Reciprocal regulation of microRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells.
6 Lerman et al. PLoS ONE 2011 21687694 MiRNA expression in psoriatic skin: reciprocal regulation of hsa-miR-99a and IGF-1R.
7 Li et al. J. Biol. Chem. 2011 21878637 MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma.
8 Sun et al. Oncogene 2014 23503464 Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells.
9 Wang et al. Med. Oncol. 2014 24668416 miR-99a and -99b inhibit cervical cancer cell proliferation and invasion by targeting mTOR signaling pathway.
10 Li et al. Br. J. Cancer 2013 24030073 MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathways.
11 Sun et al. Med. Oncol. 2013 23292834 MicroRNA-99a/100 promotes apoptosis by targeting mTOR in human esophageal squamous cell carcinoma.
12 Turcatel et al. PLoS ONE 2012 22299047 MIR-99a and MIR-99b modulate TGF-β induced epithelial to mesenchymal plasticity in normal murine mammary gland cells.
13 Yang et al. Cell Prolif. 2014 25348507 miR-99a directly targets the mTOR signalling pathway in breast cancer side population cells.
14 Chen et al. PLoS ONE 2013 24312487 MicroRNA-99 family members suppress Homeobox A1 expression in epithelial cells.
15 Zhang et al. Oncotarget 2014 24810364 Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a.
16 Yan et al. Mol Med Rep 2012 22751686 Downregulation of microRNA 99a in oral squamous cell carcinomas contributes to the growth and survival of oral cancer cells.
17 Gu et al. J Surg Oncol 2013 23893385 Clinic significance of microRNA-99a expression in human lung adenocarcinoma.
18 Hu et al. PLoS ONE 2014 24637915 MiR-99a antitumor activity in human breast cancer cells through targeting of mTOR expression.
19 Cui et al. BMC Cancer 2012 23173671 MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma.
20 Li et al. PLoS ONE 2013 23762265 Insulin promotes glucose consumption via regulation of miR-99a/mTOR/PKM2 pathway.
21 Zhang et al. Oncogenesis 2014 24732044 MiRNA-99a directly regulates AGO2 through translational repression in hepatocellular carcinoma.
22 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
23 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
24 Kuo et al. Oral Dis 2014 23731011 MiR-99a exerts anti-metastasis through inhibiting myotubularin-related protein 3 expression in oral cancer.
25 Mueller et al. Oncogene 2013 22525276 The miR-99 family regulates the DNA damage response through its target SNF2H.
26 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
27 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
28 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
29 Zhang et al. Cancer Cell Int. 2013 24191888 MiR-99a may serve as a potential oncogene in pediatric myeloid leukemia.
30 Lu et al. PLoS ONE 2012 22815788 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.
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