Targets miRBase

  1. Dashboard
  2. Targets

hsa-miR-31-5p (MIMAT0000089) (164 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-31-5p RHOA
qRT-PCR [1] [2] [3]
Western blot [1] [2] [3]
Luciferase reporter assay [1]
hsa-miR-31-5p PPP2R2A
qRT-PCR [4]
Luciferase reporter assay [4]
hsa-miR-31-5p LATS2
qRT-PCR [4]
Luciferase reporter assay [4]
hsa-miR-31-5p FOXP3
qRT-PCR [5] [6]
Western blot [6]
Luciferase reporter assay [6]
hsa-miR-31-5p SELE
Northern blot [7]
qRT-PCR [7]
Western blot [7]
Immunocytochemistry [7]
hsa-miR-31-5p CASR
LacZ reporter assay [8]
hsa-miR-31-5p ITGA5
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
hsa-miR-31-5p MPRIP
qRT-PCR [1]
Luciferase reporter assay [1]
hsa-miR-31-5p MMP16
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
hsa-miR-31-5p RDX
qRT-PCR [1]
Western blot [1] [9]
Luciferase reporter assay [1]
hsa-miR-31-5p FZD3
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
hsa-miR-31-5p DMD
qRT-PCR [10]
Western blot [10]
Luciferase reporter assay [10]
hsa-miR-31-5p TIAM1
Northern blot [11]
qRT-PCR [11]
microarray [11]
Luciferase reporter assay [11]
hsa-miR-31-5p DKK1
qRT-PCR [12]
microarray [12]
Western blot [12]
Luciferase reporter assay [12]
Immunoprecipitaion [12]
hsa-miR-31-5p DACT3
qRT-PCR [12]
microarray [12]
Western blot [12]
Luciferase reporter assay [12]
Immunoprecipitaion [12]
hsa-miR-31-5p WASF3
qRT-PCR [13]
GFP reporter assay [13]
Immunoblot [13]
hsa-miR-31-5p HIF1AN
Northern blot [14]
qRT-PCR [14]
Western blot [14]
CLASH [15]
hsa-miR-31-5p SATB2
qRT-PCR [16]
In situ hybridization [17]
Western blot [16] [17]
Luciferase reporter assay [16] [18] [17]
PAR-CLIP [19] [20]
hsa-miR-31-5p PRKCE
Luciferase reporter assay [21]
hsa-miR-31-5p RASA1
qRT-PCR [22]
Western blot [22]
Luciferase reporter assay [22]
hsa-miR-31-5p STK40
Luciferase reporter assay [23]
CLASH [15]
hsa-miR-31-5p MCM2
Luciferase reporter assay [24]
hsa-miR-31-5p CDK1
Luciferase reporter assay [24]
hsa-miR-31-5p CREG1
qRT-PCR [25]
Immunofluorescence [25]
Western blot [25]
Luciferase reporter assay [25]
hsa-miR-31-5p MLH1
Luciferase reporter assay [26]
hsa-miR-31-5p MET
qRT-PCR [27]
Immunoblot [27]
Luciferase reporter assay [28] [27] [29]
Immunohistochemistry [27]
hsa-miR-31-5p PPIL2
CLASH [15]
hsa-miR-31-5p ZC3H18
CLASH [15]
hsa-miR-31-5p RPS7
CLASH [15]
hsa-miR-31-5p MED12
CLASH [15]
hsa-miR-31-5p CYP27B1
CLASH [15]
hsa-miR-31-5p HIST1H2BC
CLASH [15]
hsa-miR-31-5p PTPRJ
CLASH [15]
hsa-miR-31-5p AGO1
CLASH [15]
hsa-miR-31-5p DNAAF5
CLASH [15]
hsa-miR-31-5p HIST1H2BK
CLASH [15]
hsa-miR-31-5p RPA1
CLASH [15]
hsa-miR-31-5p TXNDC5
CLASH [15]
hsa-miR-31-5p AKAP8L
CLASH [15]
hsa-miR-31-5p FLNA
CLASH [15]
hsa-miR-31-5p ATP2A2
CLASH [15]
hsa-miR-31-5p NDFIP2
CLASH [15]
hsa-miR-31-5p TRIB3
CLASH [15]
hsa-miR-31-5p NUP188
CLASH [15]
hsa-miR-31-5p RPS4Y1
CLASH [15]
hsa-miR-31-5p GLI2
CLASH [15]
hsa-miR-31-5p RPL37A
CLASH [15]
hsa-miR-31-5p EXOSC5
CLASH [15]
hsa-miR-31-5p DDX19A
CLASH [15]
hsa-miR-31-5p UBA6
CLASH [15]
hsa-miR-31-5p NOL9
CLASH [15]
hsa-miR-31-5p DNAJC5
CLASH [15]
hsa-miR-31-5p RETREG3
CLASH [15]
hsa-miR-31-5p PEX19
CLASH [15]
hsa-miR-31-5p PPP4R3B
CLASH [15]
hsa-miR-31-5p TRRAP
CLASH [15]
hsa-miR-31-5p RANGAP1
CLASH [15]
hsa-miR-31-5p TNRC6B
CLASH [15]
hsa-miR-31-5p NOP56
CLASH [15]
hsa-miR-31-5p PCSK1N
CLASH [15]
hsa-miR-31-5p ZNF275
CLASH [15]
hsa-miR-31-5p C2CD5
CLASH [15]
hsa-miR-31-5p NFATC2IP
CLASH [15]
hsa-miR-31-5p HIST1H2BJ
CLASH [15]
hsa-miR-31-5p SRRM2
CLASH [15]
hsa-miR-31-5p GYG1
CLASH [15]
hsa-miR-31-5p ZC3H12C
CLASH [15]
hsa-miR-31-5p LRRC59
CLASH [15]
hsa-miR-31-5p GHITM
CLASH [15]
hsa-miR-31-5p EDC3
CLASH [15]
hsa-miR-31-5p MYO1D
CLASH [15]
hsa-miR-31-5p STOML2
CLASH [15]
hsa-miR-31-5p EXOC6
CLASH [15]
hsa-miR-31-5p HOXA7
CLASH [15]
hsa-miR-31-5p SFXN1
CLASH [15]
hsa-miR-31-5p ILF2
CLASH [15]
hsa-miR-31-5p SRC
qRT-PCR [27]
Immunoblot [27]
Luciferase reporter assay [27]
Immunohistochemistry [27]
hsa-miR-31-5p MAP4K4
qRT-PCR [27]
Immunoblot [27]
Luciferase reporter assay [27]
Immunohistochemistry [27]
hsa-miR-31-5p RAB27A
qRT-PCR [27]
Immunoblot [27]
Luciferase reporter assay [27]
Immunohistochemistry [27]
hsa-miR-31-5p TBXA2R
qRT-PCR [30]
microarray [30]
Western blot [30]
Luciferase reporter assay [30]
hsa-miR-31-5p EMSY
qRT-PCR [31]
5' RACE [31]
ChIP [31]
Western blot [31]
Luciferase reporter assay [31]
hsa-miR-31-5p SESN2
PAR-CLIP [32] [20]
hsa-miR-31-5p ARID1A
qRT-PCR [33]
Western blot [33]
Luciferase reporter assay [33]
Flow cytometry [33]
hsa-miR-31-5p TMEM109
PAR-CLIP [34]
hsa-miR-31-5p SP1
PAR-CLIP [32]
hsa-miR-31-5p ZNF805
PAR-CLIP [19]
hsa-miR-31-5p SNRNP27
PAR-CLIP [34]
hsa-miR-31-5p FOXC1
PAR-CLIP [32] [34]
hsa-miR-31-5p YWHAE
PAR-CLIP [20] [34] [19] [32]
hsa-miR-31-5p BAHD1
HITS-CLIP [35]
hsa-miR-31-5p ABCB9
qRT-PCR [36]
Western blot [36]
Luciferase reporter assay [36]
hsa-miR-31-5p RHOBTB1
Luciferase reporter assay [37]
hsa-miR-31-5p SP7
qRT-PCR [38]
microarray [38]
Luciferase reporter assay [38]
hsa-miR-31-5p NUDT3
PAR-CLIP [39] [40]
hsa-miR-31-5p C15orf52
PAR-CLIP [40]
hsa-miR-31-5p FOXD4
PAR-CLIP [40]
hsa-miR-31-5p FOXD4L5
PAR-CLIP [40]
hsa-miR-31-5p FOXD4L4
PAR-CLIP [40]
hsa-miR-31-5p FOXD4L1
PAR-CLIP [40]
hsa-miR-31-5p MICA
PAR-CLIP [40]
hsa-miR-31-5p PAPOLG
PAR-CLIP [40]
hsa-miR-31-5p PARP11
PAR-CLIP [34]
hsa-miR-31-5p ZDHHC6
PAR-CLIP [34]
hsa-miR-31-5p SMG1
PAR-CLIP [34]
hsa-miR-31-5p SDC4
PAR-CLIP [34]
hsa-miR-31-5p RNF111
PAR-CLIP [34]
hsa-miR-31-5p PHF12
PAR-CLIP [34]
hsa-miR-31-5p TSPAN1
PAR-CLIP [34]
hsa-miR-31-5p DPM2
PAR-CLIP [34]
hsa-miR-31-5p ATP5A1
PAR-CLIP [34]
hsa-miR-31-5p ARF1
PAR-CLIP [34]
hsa-miR-31-5p HOXD3
PAR-CLIP [32] [34]
hsa-miR-31-5p MZT1
PAR-CLIP [34] [20]
hsa-miR-31-5p MXRA7
PAR-CLIP [34]
hsa-miR-31-5p REXO2
PAR-CLIP [34]
hsa-miR-31-5p IL5RA
PAR-CLIP [41]
hsa-miR-31-5p RPL35A
PAR-CLIP [39]
hsa-miR-31-5p NF2
PAR-CLIP [39]
hsa-miR-31-5p INTU
PAR-CLIP [42]
hsa-miR-31-5p CDC42SE1
PAR-CLIP [20] [42]
hsa-miR-31-5p KLHL15
PAR-CLIP [20] [19] [32]
hsa-miR-31-5p RSRC1
PAR-CLIP [19] [32] [20]
hsa-miR-31-5p ZNF587
PAR-CLIP [19] [32] [20]
hsa-miR-31-5p ZNF641
PAR-CLIP [19] [20]
hsa-miR-31-5p BCAS4
PAR-CLIP [19]
hsa-miR-31-5p PARP1
PAR-CLIP [19] [32]
hsa-miR-31-5p FRK
PAR-CLIP [43]
hsa-miR-31-5p SFT2D2
PAR-CLIP [43]
hsa-miR-31-5p AR
PAR-CLIP [43]
hsa-miR-31-5p CNBP
PAR-CLIP [20]
hsa-miR-31-5p GUF1
PAR-CLIP [20]
hsa-miR-31-5p ZNF460
PAR-CLIP [32] [20]
hsa-miR-31-5p TOR1AIP1
PAR-CLIP [20]
hsa-miR-31-5p ZNF331
PAR-CLIP [20]
hsa-miR-31-5p C19orf12
PAR-CLIP [20]
hsa-miR-31-5p ECHDC1
PAR-CLIP [20]
hsa-miR-31-5p ZNF678
PAR-CLIP [20]
hsa-miR-31-5p CCDC127
PAR-CLIP [20]
hsa-miR-31-5p ZIK1
PAR-CLIP [32] [20]
hsa-miR-31-5p SYDE2
PAR-CLIP [20]
hsa-miR-31-5p PYURF
PAR-CLIP [20]
hsa-miR-31-5p LAPTM4A
PAR-CLIP [20]
hsa-miR-31-5p FZD1
PAR-CLIP [32]
hsa-miR-31-5p GTF2E1
PAR-CLIP [32]
hsa-miR-31-5p CCNT1
PAR-CLIP [32]
hsa-miR-31-5p SPRTN
PAR-CLIP [32]
hsa-miR-31-5p SLC18B1
PAR-CLIP [32]
hsa-miR-31-5p QSER1
PAR-CLIP [32]
hsa-miR-31-5p CKAP2L
HITS-CLIP [44]
PAR-CLIP [32]
hsa-miR-31-5p SRPX2
HITS-CLIP [44]
hsa-miR-31-5p LILRA2
HITS-CLIP [44]
hsa-miR-31-5p LIPG
HITS-CLIP [44]
hsa-miR-31-5p IPP
HITS-CLIP [44]
hsa-miR-31-5p PPM1L
HITS-CLIP [44]
hsa-miR-31-5p RPL27A
HITS-CLIP [44]
hsa-miR-31-5p RPL12
HITS-CLIP [45]
hsa-miR-31-5p XPO6
HITS-CLIP [35]
hsa-miR-31-5p ACBD7
HITS-CLIP [35]
hsa-miR-31-5p JARID2
HITS-CLIP [35]
hsa-miR-31-5p AKNA
HITS-CLIP [35]
hsa-miR-31-5p AFF1
HITS-CLIP [46]
hsa-miR-31-5p DPYSL5
HITS-CLIP [47]
hsa-miR-31-5p FAM193A
HITS-CLIP [47]
hsa-miR-31-5p MCMBP
HITS-CLIP [47]

References

authors journal year Pubmed link title
1 Valastyan et al. Cell 2009 19524507 A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis.
2 Fan et al. Arthritis Rheum. 2012 22736314 Identification of microRNA-31 as a novel regulator contributing to impaired interleukin-2 production in T cells from patients with systemic lupus erythematosus.
3 Chang et al. Oral Oncol. 2013 22854067 Passenger strand miRNA miR-31* regulates the phenotypes of oral cancer cells by targeting RhoA.
4 Liu et al. J. Clin. Invest. 2010 20237410 MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors.
5 Kresowik et al. Biol. Reprod. 2014 24855107 MicroRNA-31 is significantly elevated in both human endometrium and serum during the window of implantation: a potential biomarker for optimum receptivity.
6 Rouas et al. Eur. J. Immunol. 2009 19408243 Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression.
7 Suárez et al. J. Immunol. 2010 19949084 Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation.
8 Liu et al. Cancer Res. 2010 20145132 miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma.
9 Hua et al. Oncol. Rep. 2012 22089331 Human miR-31 targets radixin and inhibits migration and invasion of glioma cells.
10 Cacchiarelli et al. EMBO Rep. 2011 21212803 miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy.
11 Cottonham et al. J. Biol. Chem. 2010 20826792 miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells.
12 Xi et al. PLoS ONE 2010 21048943 Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells.
13 Sossey-Alaoui et al. Int. J. Cancer 2011 21105030 WAVE3, an actin remodeling protein, is regulated by the metastasis suppressor microRNA, miR-31, during the invasion-metastasis cascade.
14 Peng et al. FASEB J. 2012 22532441 MicroRNA-31 targets FIH-1 to positively regulate corneal epithelial glycogen metabolism.
15 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
16 Xie et al. Biochem. Biophys. Res. Commun. 2014 24565840 Effects of miR-31 on the osteogenesis of human mesenchymal stem cells.
17 Yang et al. PLoS ONE 2013 24386467 Elevated microRNA-31 expression regulates colorectal cancer progression by repressing its target gene SATB2.
18 Aprelikova et al. Cell Cycle 2010 20980827 The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.
19 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
20 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
21 Körner et al. J. Biol. Chem. 2013 23364795 MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon (PKCepsilon).
22 Sun et al. J. Biol. Chem. 2013 23322774 MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1 (RASA1).
23 Xu et al. J. Immunol. 2013 23233723 MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40.
24 Lin et al. Cancer Res. 2013 23233736 Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.
25 Wang et al. Exp. Cell Res. 2013 23518389 MicroRNA-31 controls phenotypic modulation of human vascular smooth muscle cells by regulating its target gene cellular repressor of E1A-stimulated genes.
26 Zhong et al. Tumour Biol. 2013 23539435 MicroRNA-31-5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells.
27 Asangani et al. Oncotarget 2012 22948084 Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma.
28 Giglio et al. J. Cell. Physiol. 2013 23553486 MicroRNA miR-24 promotes cell proliferation by targeting the CDKs inhibitors p27Kip1 and p16INK4a.
29 Mitamura et al. Oncogenesis 2013 23552883 Downregulation of miRNA-31 induces taxane resistance in ovarian cancer cells through increase of receptor tyrosine kinase MET.
30 Wang et al. Arterioscler. Thromb. Vasc. Biol. 2014 24558106 Deficiency of the microRNA-31-microRNA-720 pathway in the plasma and endothelial progenitor cells from patients with coronary artery disease.
31 Viré et al. Mol. Cell 2014 24582497 The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31.
32 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
33 Wang et al. Gynecol. Oncol. 2014 24793973 MiR-31 is an independent prognostic factor and functions as an oncomir in cervical cancer via targeting ARID1A.
34 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
35 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
36 Dong et al. Cancer Lett. 2014 24099915 MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9.
37 Xu et al. Int. J. Oncol. 2013 23258531 The tumor suppressor gene RhoBTB1 is a novel target of miR-31 in human colon cancer.
38 Baglìo et al. Gene 2013 23827457 MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31.
39 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
40 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
41 Majoros et al. Nat. Methods 2013 23708386 MicroRNA target site identification by integrating sequence and binding information.
42 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
43 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
44 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
45 Kishore et al. Genome Biol. 2013 23706177 Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing.
46 Haecker et al. PLoS Pathog. 2012 22927820 Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas.
47 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
Imprint Data protection