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hsa-miR-27a-3p (MIMAT0000084) (386 targets) in miRTarBase

References

authors journal year Pubmed link title
1 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
2 Myatt et al. Cancer Res. 2010 20028871 Definition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancer.
3 Guttilla et al. J. Biol. Chem. 2009 19574223 Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells.
4 Mozos et al. Hum. Pathol. 2014 24746199 The FOXO1-miR27 tandem regulates myometrial invasion in endometrioid endometrial adenocarcinoma.
5 Zhou et al. J Surg Oncol 2012 22213032 Mechanism and function of decreased FOXO1 in renal cell carcinoma.
6 Fletcher et al. Hum. Mol. Genet. 2012 22505583 Androgen-regulated processing of the oncomir miR-27a, which targets Prohibitin in prostate cancer.
7 Liu et al. Cancer Lett. 2009 18789835 MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin.
8 Kang et al. J. Biol. Chem. 2013 24133204 MicroRNA-27 (miR-27) targets prohibitin and impairs adipocyte differentiation and mitochondrial function in human adipose-derived stem cells.
9 Tang et al. Oncogene 2014 23752185 miR-27a regulates endothelial differentiation of breast cancer stem like cells.
10 Sun et al. Cancer Sci. 2010 20666778 Hsa-mir-27a genetic variant contributes to gastric cancer susceptibility through affecting miR-27a and target gene expression.
11 Mertens-Talcott et al. Cancer Res. 2007 18006846 The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells.
12 Li et al. Endocrinology 2010 20382698 MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells.
13 Ma et al. Mol. Cell. Biol. 2013 23918807 A feedback loop consisting of microRNA 23a/27a and the β-like globin suppressors KLF3 and SP1 regulates globin gene expression.
14 Li et al. Gynecol. Oncol. 2010 20624637 MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells.
15 Nishi et al. Mol. Cell. Biol. 2011 21149577 MicroRNA-27a regulates beta cardiac myosin heavy chain gene expression by targeting thyroid hormone receptor beta1 in neonatal rat ventricular myocytes.
16 Ma et al. Cancer Lett. 2010 20638779 miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2.
17 Li et al. J. Biol. Chem. 2013 23649631 c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2.
18 Acunzo et al. Proc. Natl. Acad. Sci. U.S.A. 2013 23650389 Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2.
19 Wuchty et al. PLoS ONE 2011 21358821 Prediction of Associations between microRNAs and Gene Expression in Glioma Biology.
20 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
21 Park et al. Gene 2014 24487055 MicroRNA-27 promotes the differentiation of odontoblastic cell by targeting APC and activating Wnt/β-catenin signaling.
22 Zhang et al. Cancer Genet 2011 22018270 miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition.
23 Wang et al. Oncogene 2011 21460851 Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen.
24 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
25 McKinsey et al. Oncogene 2011 21643012 A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs.
26 Crist et al. Proc. Natl. Acad. Sci. U.S.A. 2009 19666532 Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression.
27 Tardif et al. BMC Musculoskelet Disord 2009 19948051 Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.
28 Portal et al. Proc. Natl. Acad. Sci. U.S.A. 2011 21558443 MicroRNA-27a regulates basal transcription by targeting the p44 subunit of general transcription factor IIH.
29 Zhang et al. Atherosclerosis 2014 24608080 MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages.
30 Mo et al. PLoS ONE 2013 23451058 Identification of novel AR-targeted microRNAs mediating androgen signalling through critical pathways to regulate cell viability in prostate cancer.
31 Riley et al. EMBO J. 2012 22473208 EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency.
32 Narasimhan et al. PLoS ONE 2012 23236440 Identification of novel microRNAs in post-transcriptional control of Nrf2 expression and redox homeostasis in neuronal, SH-SY5Y cells.
33 Wang et al. Cell Death Dis 2013 23559009 Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression.
34 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
35 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
36 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
37 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
38 Lu et al. PLoS ONE 2012 22815788 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.
39 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
40 Urbich et al. Blood 2012 22184411 MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A.
41 Zhao et al. J. Exp. Clin. Cancer Res. 2011 21569481 Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells.
42 Scheibner et al. PLoS ONE 2012 23236401 MiR-27a functions as a tumor suppressor in acute leukemia by regulating 14-3-3θ.
43 Drayton et al. Clin. Cancer Res. 2014 24516043 Reduced expression of miRNA-27a modulates cisplatin resistance in bladder cancer by targeting the cystine/glutamate exchanger SLC7A11.
44 Pan et al. Cell. Physiol. Biochem. 2014 24556602 MicroRNA-27a promotes proliferation, migration and invasion by targeting MAP2K4 in human osteosarcoma cells.
45 Kang et al. PLoS ONE 2013 24244514 Hypoxia mediates mutual repression between microRNA-27a and PPARγ in the pulmonary vasculature.
46 Yang et al. Oncogene 2014 23246964 Genetic variations in miR-27a gene decrease mature miR-27a level and reduce gastric cancer susceptibility.
47 Choi et al. PLoS ONE 2014 24824429 MicroRNA-27a modulates HCV infection in differentiated hepatocyte-like cells from adipose tissue-derived mesenchymal stem cells.
48 Ell et al. J. Biol. Chem. 2014 24966325 The microRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasis-suppressive gene prosaposin.
49 Ahn et al. J. Biol. Chem. 2013 23322776 SON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 cluster.
50 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
51 Liu et al. PLoS ONE 2013 24086481 MiR-27a regulates apoptosis in nucleus pulposus cells by targeting PI3K.
52 Guo et al. Mol. Cell 2014 24725595 Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function.
53 Offer et al. Mol. Cancer Ther. 2014 24401318 microRNAs miR-27a and miR-27b directly regulate liver dihydropyrimidine dehydrogenase expression through two conserved binding sites.
54 Zhu et al. Oncol. Rep. 2014 24154848 microRNA-27a functions as a tumor suppressor in esophageal squamous cell carcinoma by targeting KRAS.
55 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
56 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
57 Kishore et al. Genome Biol. 2013 23706177 Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing.
58 Pillai et al. Breast Cancer Res. Treat. 2014 24906430 HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.
59 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
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