Targets miRBase

hsa-miR-26a-5p (MIMAT0000082) (409 targets) in miRTarBase

References

authors journal year Pubmed link title
1 Palmieri et al. Oncogene 2012 22139073 Downregulation of HMGA-targeting microRNAs has a critical role in human pituitary tumorigenesis.
2 Liang et al. Cell Death Dis 2014 24853416 Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis.
3 Visone et al. Oncogene 2007 17563749 Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.
4 Zhou et al. Int. J. Oncol. 2014 24682444 MicroRNA-26a acts as a tumor suppressor inhibiting gallbladder cancer cell proliferation by directly targeting HMGA2.
5 Lin et al. FEBS Lett. 2013 23796420 miR-26a inhibits proliferation and motility in bladder cancer by targeting HMGA1.
6 Li et al. Diabetes Res. Clin. Pract. 2012 22245693 Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells.
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8 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
9 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
10 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
11 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
12 Kim et al. Proc. Natl. Acad. Sci. U.S.A. 2010 20080666 Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship.
13 Liu et al. Biochim. Biophys. Acta 2012 22885155 MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN.
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15 Huse et al. Genes Dev. 2009 19487573 The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo.
16 Guo et al. Biochem. Biophys. Res. Commun. 2013 24140063 C-Myc negatively controls the tumor suppressor PTEN by upregulating miR-26a in glioblastoma multiforme cells.
17 Lu et al. Cancer Res. 2011 21199804 MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2.
18 Alajez et al. Cell Death Dis 2010 21368858 Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98.
19 Yip et al. PLoS ONE 2011 21829663 Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development.
20 Yu et al. Oncol Lett 2013 23599767 miR-26a inhibits invasion and metastasis of nasopharyngeal cancer by targeting EZH2.
21 Cao et al. Mol. Cancer 2010 20478051 MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta.
22 Zhang et al. Carcinogenesis 2011 20952513 Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer.
23 Wong et al. J. Biol. Chem. 2008 18281287 MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis.
24 Sander et al. Blood 2008 18713946 MYC stimulates EZH2 expression by repression of its negative regulator miR-26a.
25 Volinia et al. Proc. Natl. Acad. Sci. U.S.A. 2006 16461460 A microRNA expression signature of human solid tumors defines cancer gene targets.
26 Beitzinger et al. RNA Biol 2007 17637574 Identification of human microRNA targets from isolated argonaute protein complexes.
27 Luzi et al. J. Bone Miner. Res. 2008 18197755 Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor.
28 et al. None 17922609
29 Leeper et al. J. Cell. Physiol. 2011 20857419 MicroRNA-26a is a novel regulator of vascular smooth muscle cell function.
30 Dey et al. Genes Dev. 2012 23028144 miR-26a is required for skeletal muscle differentiation and regeneration in mice.
31 Icli et al. Circ. Res. 2013 24047927 MicroRNA-26a regulates pathological and physiological angiogenesis by targeting BMP/SMAD1 signaling.
32 Lewis et al. Cell 2003 14697198 Prediction of mammalian microRNA targets.
33 Zhang et al. Mol. Biol. Rep. 2013 23108995 MiR-26a regulates cell cycle and anoikis of human esophageal adenocarcinoma cells through Rb1-E2F1 signaling pathway.
34 Witwer et al. J. Immunol. 2010 20130213 MicroRNA regulation of IFN-beta protein expression: rapid and sensitive modulation of the innate immune response.
35 Mohamed et al. J. Biol. Chem. 2010 20525681 Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3β.
36 Zhang et al. Gastroenterology 2012 22484120 MicroRNA-26a promotes cholangiocarcinoma growth by activating β-catenin.
37 Morgan et al. Nucleic Acids Res. 2010 20660482 CPEB2, CPEB3 and CPEB4 are coordinately regulated by miRNAs recognizing conserved binding sites in paralog positions of their 3'-UTRs.
38 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
39 Hildebrand et al. J. Invest. Dermatol. 2011 20827281 A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo.
40 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
41 Zhu et al. Nucleic Acids Res. 2012 22210897 MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein.
42 Riley et al. EMBO J. 2012 22473208 EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency.
43 Chen et al. Mol. Ther. 2011 21610700 Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways.
44 Sun et al. FEBS Lett. 2012 22673513 MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7.
45 Salvatori et al. Cell Death Dis 2012 23096114 The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells.
46 Zhu et al. J. Pathol. 2013 23338972 NPM-ALK up-regulates iNOS expression through a STAT3/microRNA-26a-dependent mechanism.
47 Yang et al. Hepatology 2013 23389848 MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin-6-Stat3 pathway.
48 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
49 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
50 Gao et al. PLoS ONE 2013 23750239 MiR-26a inhibits proliferation and migration of breast cancer through repression of MCL-1.
51 Tan et al. Breast Cancer Res. 2014 24735615 Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2.
52 Lv et al. PLoS ONE 2013 23861775 miR-26a and its target CKS2 modulate cell growth and tumorigenesis of papillary thyroid carcinoma.
53 Gentilin et al. Endocrinology 2013 23525216 miR-26a plays an important role in cell cycle regulation in ACTH-secreting pituitary adenomas by modulating protein kinase Cδ.
54 Reuland et al. J. Invest. Dermatol. 2013 23190898 MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD).
55 Deng et al. PLoS ONE 2013 24015269 miR-26a suppresses tumor growth and metastasis by targeting FGF9 in gastric cancer.
56 Mura et al. PLoS ONE 2012 23227223 The role of the 3'UTR region in the regulation of the ACVR1/Alk-2 gene expression.
57 Erdmann et al. BMC Cancer 2014 24517338 Elevated expression of prostate cancer-associated genes is linked to down-regulation of microRNAs.
58 Guo et al. Exp. Cell Res. 2014 24211747 MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated.
59 Lee et al. Oncogenesis 2013 23689287 Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival.
60 Yang et al. Hepatology 2014 24259426 MicroRNA-26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor-cMet pathway.
61 Fu et al. Oncogene 2014 24056962 miR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis.
62 Jia et al. Int. J. Cancer 2014 24343426 Expression, regulation and roles of miR-26a and MEG3 in tongue squamous cell carcinoma.
63 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
64 Lezina et al. Cell Death Dis 2013 24336073 miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress.
65 Fu et al. Proc. Natl. Acad. Sci. U.S.A. 2013 24114270 MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation.
66 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
67 Karbiener et al. Stem Cells 2014 24375761 MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes.
68 Chai et al. PLoS ONE 2013 24194905 MicroRNA-26a inhibits angiogenesis by down-regulating VEGFA through the PIK3C2α/Akt/HIF-1α pathway in hepatocellular carcinoma.
69 Qian et al. CNS Neurosci Ther 2013 23870455 MicroRNA-26a promotes tumor growth and angiogenesis in glioma by directly targeting prohibitin.
70 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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