Targets miRBase

hsa-miR-21-5p (MIMAT0000076) (569 targets) in miRTarBase

References

authors journal year Pubmed link title
1 Pan et al. J. Immunol. 2010 20483747 MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1.
2 Gabriely et al. Mol. Cell. Biol. 2008 18591254 MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators.
3 Riley et al. EMBO J. 2012 22473208 EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency.
4 Wang et al. Cancer Res. 2009 19826040 microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells.
5 Dellago et al. Aging Cell 2013 23496142 High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan.
6 Yang et al. Proteomics 2009 19253296 Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach.
7 Frankel et al. J. Biol. Chem. 2008 17991735 Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells.
8 Yao et al. Biochem. Biophys. Res. Commun. 2009 19682430 MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells.
9 Zhu et al. Cell Res. 2008 18270520 MicroRNA-21 targets tumor suppressor genes in invasion and metastasis.
10 Allgayer et al. Crit. Rev. Oncol. Hematol. 2010 19836969 Pdcd4, a colon cancer prognostic that is regulated by a microRNA.
11 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
12 Nielsen et al. Clin. Exp. Metastasis 2011 21069438 High levels of microRNA-21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer patients.
13 Talotta et al. Oncogene 2009 18850008 An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation.
14 Li et al. Hepatology 2009 19133651 MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma.
15 Hiyoshi et al. Clin. Cancer Res. 2009 19276261 MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma.
16 Asangani et al. Oncogene 2008 17968323 MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer.
17 Bethke et al. Science 2009 19342589 Nuclear hormone receptor regulation of microRNAs controls developmental progression.
18 Huang et al. J. Biol. Chem. 2009 19419954 Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.
19 Roldo et al. J. Clin. Oncol. 2006 16966691 MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior.
20 Friedland et al. Otol. Neurotol. 2009 19672202 Cholesteatoma growth and proliferation: posttranscriptional regulation by microRNA-21.
21 Lu et al. Oncogene 2008 18372920 MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene.
22 Hashimi et al. Blood 2009 19398721 MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation.
23 Selcuklu et al. Biochem. Biophys. Res. Commun. 2012 22618231 Regulatory interplay between miR-21, JAG1 and 17beta-estradiol (E2) in breast cancer cells.
24 Buckley et al. Nature 2009 19242418 Is REST a regulator of pluripotency?
25 Kwak et al. Oncogene 2011 21278789 Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas.
26 Sayed et al. Mol. Biol. Cell 2008 18508928 MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths.
27 Mei et al. J. Cell. Biochem. 2013 23239100 miR-21 modulates the ERK-MAPK signaling pathway by regulating SPRY2 expression during human mesenchymal stem cell differentiation.
28 Song et al. J. Exp. Clin. Cancer Res. 2010 20346171 MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression.
29 Guinea-Viniegra et al. Sci Transl Med 2014 24574341 Targeting miR-21 to treat psoriasis.
30 Zhang et al. Urology 2011 21820586 miR-21 modulates cell apoptosis by targeting multiple genes in renal cell carcinoma.
31 Wang et al. Dig. Dis. Sci. 2013 23504349 MiR-21 down-regulation suppresses cell growth, invasion and induces cell apoptosis by targeting FASL, TIMP3, and RECK genes in esophageal carcinoma.
32 Chen et al. Cancer Lett. 2008 19013014 MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G.
33 Zhang et al. Lab. Invest. 2008 18794849 miR-21 plays a pivotal role in gastric cancer pathogenesis and progression.
34 Shi et al. Cancer Res. 2013 23811941 AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression.
35 Loayza-Puch et al. Oncogene 2010 20154725 Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs.
36 Fan et al. Exp. Mol. Pathol. 2014 24594117 MicroRNA-21 is a unique signature associated with coronary plaque instability in humans by regulating matrix metalloproteinase-9 via reversion-inducing cysteine-rich protein with Kazal motifs.
37 Ziyan et al. Med. Oncol. 2011 20480266 MicroRNA-21 is involved in osteosarcoma cell invasion and migration.
38 Zhou et al. Int. J. Oncol. 2013 23708209 MicroRNA-21 regulates the migration and invasion of a stem-like population in hepatocellular carcinoma.
39 Han et al. CNS Neurosci Ther 2012 22630347 MicroRNA-21 expression is regulated by β-catenin/STAT3 pathway and promotes glioma cell invasion by direct targeting RECK.
40 Bhat-Nakshatri et al. Nucleic Acids Res. 2009 19528081 Estradiol-regulated microRNAs control estradiol response in breast cancer cells.
41 Pan et al. Mol. Hum. Reprod. 2010 19906824 microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells.
42 Papagiannakopoulos et al. Cancer Res. 2008 18829576 MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells.
43 Mishra et al. Oncogene 2014 24037531 Androgen receptor and microRNA-21 axis downregulates transforming growth factor beta receptor II (TGFBR2) expression in prostate cancer.
44 Kim et al. Stem Cells 2009 19816956 MiR-21 regulates adipogenic differentiation through the modulation of TGF-beta signaling in mesenchymal stem cells derived from human adipose tissue.
45 Yu et al. Carcinogenesis 2012 22072622 MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFβR2) in colon cancer cells.
46 Lu et al. Nucleic Acids Res. 2009 19136465 A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference.
47 Li et al. Biochem. Biophys. Res. Commun. 2014 24690174 Higher LRRFIP1 expression in glioblastoma multiforme is associated with better response to teniposide, a type II topoisomerase inhibitor.
48 Li et al. Brain Res. 2009 19559015 MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme.
49 Li et al. Biochem. Biophys. Res. Commun. 2009 19302977 MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells.
50 Zhu et al. J. Biol. Chem. 2007 17363372 MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).
51 Wang et al. Arterioscler. Thromb. Vasc. Biol. 2011 21817107 MicroRNA-21 regulates vascular smooth muscle cell function via targeting tropomyosin 1 in arteriosclerosis obliterans of lower extremities.
52 Fujita et al. J. Mol. Biol. 2008 18384814 miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism.
53 Yang et al. Toxicol. Lett. 2014 24821435 miR-21 regulates N-methyl-N-nitro-N'-nitrosoguanidine-induced gastric tumorigenesis by targeting FASLG and BTG2.
54 Leone et al. Clin. Cancer Res. 2013 23446999 Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth.
55 Liu et al. Cell Res. 2009 19546886 Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma.
56 Sun et al. Tumour Biol. 2013 23857284 Expression and significance of miRNA-21 and BTG2 in lung cancer.
57 Lu et al. PLoS ONE 2012 22815788 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.
58 Zhou et al. Lab. Invest. 2010 20048743 Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status.
59 Yamanaka et al. Blood 2009 19641183 Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia.
60 Reis et al. Mol. Cancer 2010 20831814 Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma.
61 Wickramasinghe et al. Nucleic Acids Res. 2009 19264808 Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells.
62 Gu et al. Med. Oncol. 2011 20143188 miRNA-21 regulates arsenic-induced anti-leukemia activity in myelogenous cell lines.
63 Tomimaru et al. Br. J. Cancer 2010 20978511 MicroRNA-21 induces resistance to the anti-tumour effect of interferon-α/5-fluorouracil in hepatocellular carcinoma cells.
64 Motoyama et al. Int. J. Oncol. 2010 20372781 Clinicopathological and prognostic significance of PDCD4 and microRNA-21 in human gastric cancer.
65 Saxena et al. Eur. J. Cancer 2013 23827854 Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression.
66 Cao et al. J. Cancer Res. Clin. Oncol. 2012 22212233 PDCD4 expression inversely correlated with miR-21 levels in gastric cancers.
67 Gu et al. Acta Haematol. 2013 23548551 Inhibition of miR-21 induces biological and behavioral alterations in diffuse large B-cell lymphoma.
68 Chusorn et al. Tumour Biol. 2013 23417858 Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis.
69 Wang et al. Asian Pac. J. Cancer Prev. 2015 26028073 Macrophage-secreted Exosomes Delivering miRNA-21 Inhibitor can Regulate BGC-823 Cell Proliferation.
70 Li et al. J BUON 2014 24659669 MicroRNA-21 stimulates gastric cancer growth and invasion by inhibiting the tumor suppressor effects of programmed cell death protein 4 and phosphatase and tensin homolog.
71 Yao et al. Int. J. Cancer 2011 20533548 Micro-RNA-21 regulates TGF-β-induced myofibroblast differentiation by targeting PDCD4 in tumor-stroma interaction.
72 Liu et al. Acta Biochim. Biophys. Sin. (Shanghai) 2013 23824073 Berberine sensitizes ovarian cancer cells to cisplatin through miR-21/PDCD4 axis.
73 Dong et al. Int. J. Oncol. 2012 22766763 Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells.
74 Cheng et al. Cardiovasc. Res. 2010 20219857 Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4.
75 Ujigo et al. Spine 2014 24732841 Administration of microRNA-210 promotes spinal cord regeneration in mice.
76 Yamamichi et al. Clin. Cancer Res. 2009 19509156 Locked nucleic acid in situ hybridization analysis of miR-21 expression during colorectal cancer development.
77 Wang et al. FASEB J. 2010 20056717 MicroRNA-204/211 alters epithelial physiology.
78 Iliopoulos et al. Eur. J. Immunol. 2011 21469086 The negative costimulatory molecule PD-1 modulates the balance between immunity and tolerance via miR-21.
79 Qi et al. BMC Cancer 2009 19473551 Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma.
80 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
81 Jin et al. FEBS Lett. 2013 23313253 MicroRNA-21 mediates the rapamycin-induced suppression of endothelial proliferation and migration.
82 Connolly et al. Mol. Cancer Res. 2010 20460403 Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB.
83 Sabatel et al. PLoS ONE 2011 21347332 MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cells.
84 Liu et al. FEBS Lett. 2011 21872591 miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells.
85 Zhou et al. Proc. Natl. Acad. Sci. U.S.A. 2011 21636785 MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation.
86 Sarkar et al. Am. J. Physiol. Lung Cell Mol. Physiol. 2010 20693317 MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration.
87 Qin et al. Acta Biochim. Biophys. Sin. (Shanghai) 2009 19578724 BMPRII is a direct target of miR-21.
88 Yang et al. Am. J. Physiol. Lung Cell Mol. Physiol. 2012 22227207 miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling.
89 Braun et al. Nucleic Acids Res. 2014 24510096 Rapid identification of regulatory microRNAs by miTRAP (miRNA trapping by RNA in vitro affinity purification).
90 Xiong et al. J. Proteome Res. 2012 22316494 Identification of novel miR-21 target proteins in multiple myeloma cells by quantitative proteomics.
91 Valeri et al. Proc. Natl. Acad. Sci. U.S.A. 2010 21078976 MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2).
92 Zhong et al. J. Cancer Res. Clin. Oncol. 2012 22806311 miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer.
93 Yu et al. Mol. Cancer Res. 2010 21047769 Context-dependent bidirectional regulation of the MutS homolog 2 by transforming growth factor β contributes to chemoresistance in breast cancer cells.
94 Koole et al. Nucleic Acids Res. 2013 23861444 A versatile microsatellite instability reporter system in human cells.
95 Cottonham et al. J. Biol. Chem. 2010 20826792 miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells.
96 Huang et al. Cancer Res. 2013 23442323 Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma.
97 Yelamanchili et al. Cell Death Dis 2010 21170291 MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease.
98 Yan et al. Breast Cancer Res. 2011 21219636 Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth.
99 Barker et al. Curr Opin Pharmacol 2010 20864407 Regulation of ErbB receptor signalling in cancer cells by microRNA.
100 Terao et al. J. Biol. Chem. 2011 21131358 Induction of miR-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells: biological correlates and molecular targets.
101 et al. None 21191961
102 Zheng et al. J. Cell. Biochem. 2011 21328460 miR-21 downregulates the tumor suppressor P12 CDK2AP1 and stimulates cell proliferation and invasion.
103 Vicinus et al. Oncol. Rep. 2013 23817679 miR-21 and its target gene CCL20 are both highly overexpressed in the microenvironment of colorectal tumors: significance of their regulation.
104 Yao et al. Biochim. Biophys. Acta 2012 22001440 MiR-21 is involved in cervical squamous cell tumorigenesis and regulates CCL20.
105 Yang et al. J. Cell. Physiol. 2012 22034194 MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells.
106 Wang et al. Biochem. Biophys. Res. Commun. 2013 23998932 miRNA-21 inhibition enhances RANTES and IP-10 release in MCF-7 via PIAS3 and STAT3 signalling and causes increased lymphocyte migration.
107 Kang et al. J. Biol. Chem. 2012 22158624 Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins.
108 Chang et al. J. Immunol. 2012 22387553 Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8(+) T suppressor cells.
109 Zhang et al. Cancer Lett. 2014 24012640 Blockage of a miR-21/EGFR regulatory feedback loop augments anti-EGFR therapy in glioblastomas.
110 Schramedei et al. Oncogene 2011 21317927 MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4.
111 Shin et al. Carcinogenesis 2011 21081469 NF-κB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors.
112 Risbud et al. Brain Res. 2011 22019057 Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus.
113 Mase et al. Reprod Sci 2012 22573493 MiR-21 is enriched in the RNA-induced silencing complex and targets COL4A1 in human granulosa cell lines.
114 Wang et al. Mol Oncol 2013 23177026 The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL.
115 Wang et al. J. Biol. Chem. 2010 20371612 Foxo3a regulates apoptosis by negatively targeting miR-21.
116 Francis et al. J. Biol. Chem. 2014 25118289 Regulation of the extrinsic apoptotic pathway by microRNA-21 in alcoholic liver injury.
117 Zhang et al. Cancer Res. 2012 22836756 MicroRNA-21 modulates the levels of reactive oxygen species by targeting SOD3 and TNFα.
118 Zhang et al. Urology 2012 23206776 miR-21 downregulated TCF21 to inhibit KISS1 in renal cancer.
119 Zhong et al. Diabetologia 2013 23292313 miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes.
120 Wang et al. Mol. Cell. Endocrinol. 2014 24887517 miR-21 overexpression enhances TGF-β1-induced epithelial-to-mesenchymal transition by target smad7 and aggravates renal damage in diabetic nephropathy.
121 Põlajeva et al. BMC Cancer 2012 22931209 miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma.
122 Moriyama et al. Mol. Cancer Ther. 2009 19435867 MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance.
123 Liu et al. PLoS ONE 2011 21544242 MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression.
124 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
125 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
126 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
127 Yamanaka et al. Dig Liver Dis 2012 22464652 MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer.
128 Abdelmohsen et al. Mol. Cell. Biol. 2010 20584986 miR-375 inhibits differentiation of neurites by lowering HuD levels.
129 Si et al. Oncogene 2007 17072344 miR-21-mediated tumor growth.
130 Ji et al. Circ. Res. 2007 17478730 MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation.
131 Darimipourain et al. Prostate Cancer Prostatic Dis. 2011 21826097 Transcriptional and post-transcriptional regulation of Sprouty1, a receptor tyrosine kinase inhibitor in prostate cancer.
132 Velu et al. J. Clin. Invest. 2014 24334453 Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity.
133 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
134 Sawant et al. Mol. Immunol. 2013 23416424 The Bcl6 target gene microRNA-21 promotes Th2 differentiation by a T cell intrinsic pathway.
135 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
136 Zhu et al. J. Clin. Immunol. 2013 23657402 MicroRNA-21 in scleroderma fibrosis and its function in TGF-β-regulated fibrosis-related genes expression.
137 Lu et al. Mol. Cancer Res. 2014 24699315 miR-21 targets 15-PGDH and promotes cholangiocarcinoma growth.
138 Chen et al. PLoS Pathog. 2013 23633945 HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1.
139 Zhang et al. Exp. Mol. Med. 2014 24577233 MicroRNA-21 controls the development of osteoarthritis by targeting GDF-5 in chondrocytes.
140 Xu et al. BMC Cancer 2013 24112539 MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3.
141 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
142 McClure et al. Infect. Immun. 2014 24980967 MicroRNA 21 (miR-21) and miR-181b couple with NFI-A to generate myeloid-derived suppressor cells and promote immunosuppression in late sepsis.
143 Liu et al. FEBS Lett. 2014 24983504 A feedback regulatory loop between HIF-1α and miR-21 in response to hypoxia in cardiomyocytes.
144 Mace et al. J. Surg. Res. 2013 23726431 Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells.
145 Huang et al. Virology 2014 24889251 Pseudorabies viral replication is inhibited by a novel target of miR-21.
146 Mydlarz et al. Clin. Cancer Res. 2014 24327270 Clusterin is a gene-specific target of microRNA-21 in head and neck squamous cell carcinoma.
147 Ling et al. J. Mol. Cell. Cardiol. 2013 24161401 Modulation of microRNAs in hypertension-induced arterial remodeling through the β1 and β3-adrenoreceptor pathways.
148 Li et al. Biochem. Biophys. Res. Commun. 2013 24161395 Sirt2 suppresses glioma cell growth through targeting NF-κB-miR-21 axis.
149 Zhang et al. Cell Death Differ. 2013 23933812 Negative regulation of lncRNA GAS5 by miR-21.
150 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
151 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
152 Pillai et al. Breast Cancer Res. Treat. 2014 24906430 HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.
153 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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