Targets miRBase

rno-miR-21-5p (MIMAT0000790) (12 targets) in miRTarBase

miRNA gene name experiments
rno-miR-21-5p Pdcd4
qRT-PCR [1] [2] [3] [4]
GFP reporter assay [3]
Immunofluorescence [2]
Western blot [1] [5] [6] [2] [3] [4]
Immunocytochemistry [2]
Luciferase reporter assay [5] [2] [4] [3]
Mass spectrometry [4]
rno-miR-21-5p Tpm1
microarray [7]
rno-miR-21-5p Kcnj16
microarray [7]
rno-miR-21-5p Capn8
microarray [7]
rno-miR-21-5p Pten
qRT-PCR [8] [9] [10]
microarray [9] [10] [8]
Western blot [8] [6] [9] [10]
rno-miR-21-5p Faslg
qRT-PCR [11]
In situ hybridization [11]
Immunofluorescence [11]
Western blot [11]
Luciferase reporter assay [11]
rno-miR-21-5p Tiam1
qRT-PCR [1]
Western blot [1]
rno-miR-21-5p Peli1
qRT-PCR [1]
Western blot [1]
rno-miR-21-5p Elavl4
qRT-PCR [12]
rno-miR-21-5p Ski
qRT-PCR [13]
microarray [13]
Western blot [13]
Luciferase reporter assay [13]
rno-miR-21-5p Rela
qRT-PCR [14]
microarray [14]
ChIP [14]
Western blot [14]
Luciferase reporter assay [14]
rno-miR-21-5p ZBTB7A
qRT-PCR [15]
Luciferase reporter assay [15]

References

authors journal year Pubmed link title
1 et al. None 21154462
2 Wang et al. J. Cell. Biochem. 2012 22565856 Antagonist of microRNA-21 improves balloon injury-induced rat iliac artery remodeling by regulating proliferation and apoptosis of adventitial fibroblasts and myofibroblasts.
3 Cheng et al. J. Mol. Cell. Cardiol. 2009 19336275 MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4.
4 Wei et al. Free Radic. Res. 2014 24237305 NF-κB mediated miR-21 regulation in cardiomyocytes apoptosis under oxidative stress.
5 Lin et al. J. Biol. Chem. 2009 19158092 Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells.
6 Pogribny et al. Toxicol. Appl. Pharmacol. 2009 19167416 The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation.
7 Jeyaseelan et al. Stroke 2008 18258830 MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion.
8 Ma et al. Eur. J. Appl. Physiol. 2013 23812090 Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway.
9 Ji et al. Circ. Res. 2007 17478730 MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation.
10 Li et al. J. Exp. Clin. Cancer Res. 2010 21176238 MicroRNAs involved in neoplastic transformation of liver cancer stem cells.
11 Buller et al. FEBS J. 2010 20840605 MicroRNA-21 protects neurons from ischemic death.
12 Abdelmohsen et al. Mol. Cell. Biol. 2010 20584986 miR-375 inhibits differentiation of neurites by lowering HuD levels.
13 Li et al. Cell. Signal. 2014 24388835 MiR-21 inhibits c-Ski signaling to promote the proliferation of rat vascular smooth muscle cells.
14 Rajendran et al. J. Biol. Chem. 2013 23846691 Inhibition of protein kinase C signaling maintains rat embryonic stem cell pluripotency.
15 Jin et al. J. Cell. Biochem. 2013 23355454 microRNA 21-mediated suppression of Sprouty1 by Pokemon affects liver cancer cell growth and proliferation.