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rno-miR-21-5p (MIMAT0000790) (12 targets) in miRTarBase

miRNA gene name experiments
rno-miR-21-5p Pdcd4
qRT-PCR [1] [2] [3] [4]
GFP reporter assay [2]
Immunofluorescence [1]
Western blot [5] [6] [1] [2] [3] [4]
Immunocytochemistry [1]
Luciferase reporter assay [5] [1] [3] [2]
Mass spectrometry [3]
rno-miR-21-5p Tpm1
microarray [7]
rno-miR-21-5p Kcnj16
microarray [7]
rno-miR-21-5p Capn8
microarray [7]
rno-miR-21-5p Pten
qRT-PCR [8] [9] [10]
microarray [8] [9] [10]
Western blot [6] [8] [9] [10]
rno-miR-21-5p Faslg
qRT-PCR [11]
In situ hybridization [11]
Immunofluorescence [11]
Western blot [11]
Luciferase reporter assay [11]
rno-miR-21-5p Tiam1
qRT-PCR [4]
Western blot [4]
rno-miR-21-5p Peli1
qRT-PCR [4]
Western blot [4]
rno-miR-21-5p Elavl4
qRT-PCR [12]
rno-miR-21-5p Ski
qRT-PCR [13]
microarray [13]
Western blot [13]
Luciferase reporter assay [13]
rno-miR-21-5p Rela
qRT-PCR [14]
microarray [14]
ChIP [14]
Western blot [14]
Luciferase reporter assay [14]
rno-miR-21-5p ZBTB7A
qRT-PCR [15]
Luciferase reporter assay [15]

References

authors journal year Pubmed link title
1 Wang et al. J. Cell. Biochem. 2012 22565856 Antagonist of microRNA-21 improves balloon injury-induced rat iliac artery remodeling by regulating proliferation and apoptosis of adventitial fibroblasts and myofibroblasts.
2 Cheng et al. J. Mol. Cell. Cardiol. 2009 19336275 MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4.
3 Wei et al. Free Radic. Res. 2014 24237305 NF-κB mediated miR-21 regulation in cardiomyocytes apoptosis under oxidative stress.
4 et al. None 21154462
5 Lin et al. J. Biol. Chem. 2009 19158092 Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells.
6 Pogribny et al. Toxicol. Appl. Pharmacol. 2009 19167416 The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation.
7 Jeyaseelan et al. Stroke 2008 18258830 MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion.
8 Ji et al. Circ. Res. 2007 17478730 MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation.
9 Li et al. J. Exp. Clin. Cancer Res. 2010 21176238 MicroRNAs involved in neoplastic transformation of liver cancer stem cells.
10 Ma et al. Eur. J. Appl. Physiol. 2013 23812090 Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway.
11 Buller et al. FEBS J. 2010 20840605 MicroRNA-21 protects neurons from ischemic death.
12 Abdelmohsen et al. Mol. Cell. Biol. 2010 20584986 miR-375 inhibits differentiation of neurites by lowering HuD levels.
13 Li et al. Cell. Signal. 2014 24388835 MiR-21 inhibits c-Ski signaling to promote the proliferation of rat vascular smooth muscle cells.
14 Rajendran et al. J. Biol. Chem. 2013 23846691 Inhibition of protein kinase C signaling maintains rat embryonic stem cell pluripotency.
15 Jin et al. J. Cell. Biochem. 2013 23355454 microRNA 21-mediated suppression of Sprouty1 by Pokemon affects liver cancer cell growth and proliferation.
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