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hsa-miR-133b (MIMAT0000770) (64 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-133b BCL2L2
qRT-PCR [1]
Western blot [2] [3] [4] [1]
Luciferase reporter assay [2] [3] [1]
hsa-miR-133b PKM
Immunohistochemistry [5]
hsa-miR-133b PITX3
Luciferase reporter assay [6]
FACS [6]
hsa-miR-133b PTBP2
Reporter assay [7]
hsa-miR-133b MCL1
Western blot [2] [3] [4]
Luciferase reporter assay [2] [3]
hsa-miR-133b IGF1R
Western blot [4]
Luciferase reporter assay [8]
hsa-miR-133b KCNH2
qRT-PCR [9]
Western blot [9]
Luciferase reporter assay [9]
hsa-miR-133b FSCN1
qRT-PCR [10] [11] [12] [13]
Reporter assay [12] [11]
Western blot [13] [11] [12]
Luciferase reporter assay [11] [13]
Immunohistochemistry [10]
hsa-miR-133b FAIM
qRT-PCR [14]
microarray [14]
Western blot [14]
Luciferase reporter assay [14]
hsa-miR-133b EGFR
qRT-PCR [15]
In situ hybridization [15]
Western blot [15] [16]
Luciferase reporter assay [15] [16]
Flow cytometry [15]
hsa-miR-133b FGFR1
qRT-PCR [17]
Western blot [17]
Luciferase reporter assay [17]
Immunohistochemistry [17]
hsa-miR-133b CDK13
Luciferase reporter assay [18]
hsa-miR-133b PTPRK
Luciferase reporter assay [18]
hsa-miR-133b RB1CC1
Luciferase reporter assay [18]
hsa-miR-133b CPNE3
Luciferase reporter assay [18]
hsa-miR-133b PRDM16
Luciferase reporter assay [19]
hsa-miR-133b MET
Reporter assay [20]
Western blot [4]
hsa-miR-133b ERG
Reporter assay [9]
hsa-miR-133b HCN2
Reporter assay [21]
hsa-miR-133b HCN4
qRT-PCR [21]
Reporter assay [21]
Western blot [21]
Other [21]
hsa-miR-133b STK3
qRT-PCR [22]
microarray [22]
Western blot [22]
Immunoblot [22]
Luciferase reporter assay [22]
hsa-miR-133b CDC42
qRT-PCR [23]
microarray [22]
Western blot [23]
Immunoblot [22]
Luciferase reporter assay [23] [22]
hsa-miR-133b RHOA
qRT-PCR [22]
microarray [22]
Western blot [22]
Immunoblot [22]
Luciferase reporter assay [22]
hsa-miR-133b GLI1
qRT-PCR [24]
Western blot [24]
Luciferase reporter assay [24]
hsa-miR-133b SP1
Immunofluorescence [25]
Western blot [25]
Luciferase reporter assay [25]
hsa-miR-133b TAGLN2
qRT-PCR [26]
Immunofluorescence [26]
Western blot [26]
Luciferase reporter assay [26]
hsa-miR-133b AKT1
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
hsa-miR-133b FAM160B1
HITS-CLIP [27]
hsa-miR-133b CXCR4
qRT-PCR [28]
Western blot [28]
Luciferase reporter assay [28]
hsa-miR-133b MMP9
Luciferase reporter assay [29]
hsa-miR-133b CTGF
Luciferase reporter assay [30]
hsa-miR-133b FOXL2
qRT-PCR [31]
ChIP [31]
Western blot [31]
Luciferase reporter assay [31]
hsa-miR-133b CNN2
PAR-CLIP [32]
hsa-miR-133b EMID1
PAR-CLIP [32]
hsa-miR-133b MC2R
PAR-CLIP [33]
hsa-miR-133b SESN3
PAR-CLIP [33]
hsa-miR-133b RHOQ
PAR-CLIP [33] [34]
hsa-miR-133b HIST2H2AC
PAR-CLIP [33]
hsa-miR-133b DCAKD
PAR-CLIP [34]
hsa-miR-133b ZBTB37
PAR-CLIP [34]
hsa-miR-133b RNF103-CHMP3
PAR-CLIP [27] [34]
hsa-miR-133b MYPN
PAR-CLIP [34]
hsa-miR-133b CHMP3
PAR-CLIP [27] [34]
hsa-miR-133b SYAP1
PAR-CLIP [27]
hsa-miR-133b CDK5R1
PAR-CLIP [27]
hsa-miR-133b ATP13A3
PAR-CLIP [27]
hsa-miR-133b ZFP28
PAR-CLIP [35]
hsa-miR-133b SUPT16H
PAR-CLIP [35]
hsa-miR-133b PTMA
PAR-CLIP [35]
hsa-miR-133b C11orf24
PAR-CLIP [35]
hsa-miR-133b CCDC39
HITS-CLIP [36]
hsa-miR-133b ITPKB
HITS-CLIP [36]
hsa-miR-133b CCNI
HITS-CLIP [36]
hsa-miR-133b TXNRD3NB
HITS-CLIP [36]
hsa-miR-133b PDE1A
HITS-CLIP [36]
hsa-miR-133b RBMXL1
HITS-CLIP [36]
hsa-miR-133b RNF168
HITS-CLIP [36]
hsa-miR-133b C17orf64
HITS-CLIP [36]
hsa-miR-133b ZMAT4
HITS-CLIP [36]
hsa-miR-133b TRIM71
HITS-CLIP [36]
hsa-miR-133b FOSL2
HITS-CLIP [36]
hsa-miR-133b SERPINH1
HITS-CLIP [37]
hsa-miR-133b ANGPT4
HITS-CLIP [38]
hsa-miR-133b CMTM4
HITS-CLIP [38]

References

authors journal year Pubmed link title
1 Chen et al. Cancer Cell Int. 2014 25414595 MiR-133b regulates bladder cancer cell proliferation and apoptosis by targeting Bcl-w and Akt1.
2 Abdellatif et al. Circ. Res. 2010 20056941 The role of microRNA-133 in cardiac hypertrophy uncovered.
3 Crawford et al. Biochem. Biophys. Res. Commun. 2009 19654003 MicroRNA 133B targets pro-survival molecules MCL-1 and BCL2L2 in lung cancer.
4 Zhao et al. PLoS ONE 2013 24391788 MiR-133b is down-regulated in human osteosarcoma and inhibits osteosarcoma cells proliferation, migration and invasion, and promotes apoptosis.
5 Wong et al. Int. J. Cancer 2008 18464261 Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling.
6 Kim et al. Science 2007 17761882 A MicroRNA feedback circuit in midbrain dopamine neurons.
7 Boutz et al. Genes Dev. 2007 17210790 MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development.
8 Ning et al. Differentiation 2009 19695767 MicroRNA regulation of neuron-like differentiation of adipose tissue-derived stem cells.
9 Xiao et al. J. Biol. Chem. 2007 17344217 MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts.
10 Yamamoto et al. Mod. Pathol. 2013 23196799 Fascin-1 overexpression and miR-133b downregulation in the progression of gastrointestinal stromal tumor.
11 et al. None 20198616
12 Kano et al. Int. J. Cancer 2010 21351259 miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma.
13 Guo et al. J. Exp. Clin. Cancer Res. 2014 25433493 The role of microRNA-133b and its target gene FSCN1 in gastric cancer.
14 Patron et al. PLoS ONE 2012 22532850 MiR-133b targets antiapoptotic genes and enhances death receptor-induced apoptosis.
15 Liu et al. FEBS J. 2012 22883469 MicroRNA-133b inhibits the growth of non-small-cell lung cancer by targeting the epidermal growth factor receptor.
16 Tao et al. Oncol. Rep. 2012 22407299 microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor.
17 Wen et al. Tumour Biol. 2013 23296701 miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer.
18 Mo et al. PLoS ONE 2013 23451058 Identification of novel AR-targeted microRNAs mediating androgen signalling through critical pathways to regulate cell viability in prostate cancer.
19 Yin et al. Cell Metab. 2013 23395168 MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16.
20 Hu et al. Cancer Biol. Ther. 2010 20505319 miR-133b regulates the MET proto-oncogene and inhibits the growth of colorectal cancer cells in vitro and in vivo.
21 Luo et al. J. Biol. Chem. 2008 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart.
22 Qin et al. Oncogene 2012 22179829 MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways.
23 Cheng et al. Cell. Signal. 2014 25152372 miR-133 is a key negative regulator of CDC42-PAK pathway in gastric cancer.
24 Zhao et al. BMC Cancer 2014 24443799 MiR-133b is frequently decreased in gastric cancer and its overexpression reduces the metastatic potential of gastric cancer cells.
25 Qiu et al. FEBS Lett. 2014 24613927 MiR-145, miR-133a and miR-133b inhibit proliferation, migration, invasion and cell cycle progression via targeting transcription factor Sp1 in gastric cancer.
26 Xiao et al. PLoS ONE 2014 24959893 MiR-133b regulates the expression of the Actin protein TAGLN2 during oocyte growth and maturation: a potential target for infertility therapy.
27 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
28 Duan et al. Mol. Cancer 2013 24330809 miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression.
29 Wu et al. Mol Med Rep 2014 24714873 microRNA-133b downregulation and inhibition of cell proliferation, migration and invasion by targeting matrix metallopeptidase-9 in renal cell carcinoma.
30 Robinson et al. Invest. Ophthalmol. Vis. Sci. 2013 24065814 MicroRNA signature in wound healing following excimer laser ablation: role of miR-133b on TGFβ1, CTGF, SMA, and COL1A1 expression levels in rabbit corneal fibroblasts.
31 Dai et al. FEBS Lett. 2013 23810756 MicroRNA-133b stimulates ovarian estradiol synthesis by targeting Foxl2.
32 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
33 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
34 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
35 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
36 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
37 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
38 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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