Targets miRBase

mmu-miR-221-3p (MIMAT0000669) (27 targets) in miRTarBase

miRNA gene name experiments
mmu-miR-221-3p Psmd9
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
ELISA [1]
mmu-miR-221-3p Cdkn1b
Northern blot [2]
Western blot [2]
mmu-miR-221-3p Ddit4
qRT-PCR [3]
microarray [3]
Western blot [3]
Luciferase reporter assay [3]
mmu-miR-221-3p Bnip3
qRT-PCR [3]
microarray [3]
Western blot [3]
Luciferase reporter assay [3]
mmu-miR-221-3p Kit
qRT-PCR [4] [5]
microarray [4]
Western blot [5]
Luciferase reporter assay [4] [5]
mmu-miR-221-3p Timp3
qRT-PCR [6]
mmu-miR-221-3p Arnt
qRT-PCR [7]
Western blot [7]
Immunoblot [7]
Luciferase reporter assay [7]
mmu-miR-221-3p Ubac1
HITS-CLIP [8] [9]
mmu-miR-221-3p Six4
HITS-CLIP [8] [10] [9]
mmu-miR-221-3p Tox4
HITS-CLIP [8] [9]
mmu-miR-221-3p Ehd4
HITS-CLIP [8]
mmu-miR-221-3p Arvcf
HITS-CLIP [8] [9]
mmu-miR-221-3p Ube2n
HITS-CLIP [8] [9]
mmu-miR-221-3p Fgl2
HITS-CLIP [11]
mmu-miR-221-3p Gata5
HITS-CLIP [9]
mmu-miR-221-3p 2310030G06Rik
HITS-CLIP [9]
mmu-miR-221-3p Rs1
HITS-CLIP [9]
mmu-miR-221-3p Rragd
HITS-CLIP [9]
mmu-miR-221-3p Gabpb2
HITS-CLIP [9]
mmu-miR-221-3p Spib
HITS-CLIP [9]
mmu-miR-221-3p Kcnk6
HITS-CLIP [9]
mmu-miR-221-3p Azi2
HITS-CLIP [9]
mmu-miR-221-3p Xpo7
HITS-CLIP [9]
mmu-miR-221-3p Tacc1
HITS-CLIP [9]
mmu-miR-221-3p Ftsj1
HITS-CLIP [9]
mmu-miR-221-3p Dennd5b
HITS-CLIP [9]
mmu-miR-221-3p Zfp994
HITS-CLIP [9]

References

authors journal year Pubmed link title
1 Lu et al. Blood 2011 21355095 miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1.
2 Mercatelli et al. PLoS ONE 2008 19107213 The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice.
3 Pineau et al. Proc. Natl. Acad. Sci. U.S.A. 2010 20018759 miR-221 overexpression contributes to liver tumorigenesis.
4 Felli et al. Proc. Natl. Acad. Sci. U.S.A. 2005 16330772 MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation.
5 Smorag et al. Biol. Cell 2012 22909339 MicroRNA signature in various cell types of mouse spermatogenesis: evidence for stage-specifically expressed miRNA-221, -203 and -34b-5p mediated spermatogenesis regulation.
6 Fiorentino et al. Acta Diabetol 2013 23797704 Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs.
7 Yuan et al. Hepatology 2013 22821679 MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration.
8 Zhang et al. Cell 2014 25083871 MicroRNA directly enhances mitochondrial translation during muscle differentiation.
9 Leung et al. Nat. Struct. Mol. Biol. 2011 21258322 Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs.
10 Schug et al. BMC Genomics 2013 23597149 Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver.
11 Loeb et al. Mol. Cell 2012 23142080 Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting.