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hsa-miR-200c-3p (MIMAT0000617) (177 targets) in miRTarBase

References

authors journal year Pubmed link title
1 Rebustini et al. Development 2012 22115756 miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis.
2 Cochrane et al. Mol. Cancer Ther. 2009 19435871 MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents.
3 Prislei et al. BMC Cancer 2013 23394580 MiR-200c and HuR in ovarian cancer.
4 Liu et al. Biomaterials 2013 23806972 Targeted delivery of miR-200c/DOC to inhibit cancer stem cells and cancer cells by the gelatinases-stimuli nanoparticles.
5 Cochrane et al. J Oncol 2010 20049172 Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers.
6 et al. None 21207483
7 Lo et al. J. Pathol. 2011 21294122 MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells.
8 Cao et al. Cancer Cell 2011 21840484 Coordinated regulation of polycomb group complexes through microRNAs in cancer.
9 Shimono et al. Cell 2009 19665978 Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells.
10 Park et al. Genes Dev. 2008 18381893 The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.
11 Iorio et al. Cancer Res. 2007 17875710 MicroRNA signatures in human ovarian cancer.
12 Hyun et al. Cell 2009 20005803 Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K.
13 Mees et al. Int. J. Cancer 2010 19569050 EP300--a miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas.
14 Howe et al. Breast Cancer Res. 2011 21501518 Targets of miR-200c mediate suppression of cell motility and anoikis resistance.
15 Brabletz et al. EMBO J. 2011 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells.
16 Schickel et al. Mol. Cell 2010 20620960 miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1.
17 Sass et al. BMC Syst Biol 2011 21867514 MicroRNAs coordinately regulate protein complexes.
18 Park et al. Gynecol. Oncol. 2012 22015043 The interactions between MicroRNA-200c and BRD7 in endometrial carcinoma.
19 Senanayake et al. Carcinogenesis 2012 22431721 miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.
20 Kopp et al. PLoS ONE 2012 23209748 miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression.
21 Adam et al. Clin. Cancer Res. 2009 19671845 miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy.
22 Cai et al. Graefes Arch. Clin. Exp. Ophthalmol. 2012 22183793 MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2.
23 Zhu et al. Cancer Chemother. Pharmacol. 2012 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP.
24 Chuang et al. Endocr. Relat. Cancer 2012 22685266 miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5.
25 Panda et al. Reprod Sci 2012 22569286 Endometrial miR-200c is altered during transformation into cancerous states and targets the expression of ZEBs, VEGFA, FLT1, IKKβ, KLF9, and FBLN5.
26 Oishi et al. Hepatology 2012 22707408 Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma.
27 Chuang et al. PLoS ONE 2014 24755559 miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis.
28 Hur et al. Gut 2013 22735571 MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis.
29 Lin et al. J. Cell. Biochem. 2013 22991189 miR-200c enhances radiosensitivity of human breast cancer cells.
30 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
31 Lerner et al. PLoS ONE 2012 22615771 MiR-200c regulates Noxa expression and sensitivity to proteasomal inhibitors.
32 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
33 Howe et al. PLoS ONE 2012 23185507 miR-200c targets a NF-κB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer.
34 Luna et al. PLoS ONE 2012 23272142 Regulation of trabecular meshwork cell contraction and intraocular pressure by miR-200c.
35 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
36 Cesi et al. Cell Cycle 2011 22101269 TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells.
37 Huh et al. Br. J. Cancer 2013 23807165 Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer.
38 Li et al. Mol. Cancer 2014 24997798 miRNA-200c inhibits invasion and metastasis of human non-small cell lung cancer by directly targeting ubiquitin specific peptidase 25.
39 Li et al. Mol. Carcinog. 2014 23065816 G-A variant in miR-200c binding site of EFNA1 alters susceptibility to gastric cancer.
40 Chang et al. Pathol. Oncol. Res. 2014 23821457 MicroRNA-200c regulates the sensitivity of chemotherapy of gastric cancer SGC7901/DDP cells by directly targeting RhoE.
41 Tang et al. Clin. Cancer Res. 2013 23995857 miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression.
42 Luo et al. J Transl Med 2013 23497265 A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells.
43 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
44 Shi et al. PLoS ONE 2013 24205206 MiR-200c increases the radiosensitivity of non-small-cell lung cancer cell line A549 by targeting VEGF-VEGFR2 pathway.
45 Pacurari et al. Int. J. Oncol. 2013 23708087 The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells.
46 Bai et al. Int. J. Cancer 2014 24615544 MiR-200c suppresses TGF-β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer.
47 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
48 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
49 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
50 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
51 Li et al. Int. J. Pediatr. Otorhinolaryngol. 2013 23294929 MicroRNA expression profiling and target genes study in congenital microtia.
52 Yang et al. J. Clin. Invest. 2014 24762440 ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.
53 Luo et al. Cancer Res. 2014 24786790 Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem-like cell traits in breast cancer.
54 Kopp et al. Oncotarget 2014 24368337 The proto-oncogene KRAS is targeted by miR-200c.
55 Cama et al. Acta Neuropathol. 2013 23955600 Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling.
56 Huang et al. Stem Cell Res 2014 24365599 miR-200c and GATA binding protein 4 regulate human embryonic stem cell renewal and differentiation.
57 Peng et al. Br. J. Cancer 2013 24169343 Direct targeting of SUZ12/ROCK2 by miR-200b/c inhibits cholangiocarcinoma tumourigenesis and metastasis.
58 Sun et al. Int. J. Cancer 2015 25044403 MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.
59 Tao et al. Biochim. Biophys. Acta 2014 25017995 Autoregulatory feedback loop of EZH2/miR-200c/E2F3 as a driving force for prostate cancer development.
60 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
61 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
62 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
63 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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