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mmu-miR-16-5p (MIMAT0000527) (40 targets) in miRTarBase

miRNA gene name experiments
mmu-miR-16-5p Wnt3a
Northern blot [1]
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
mmu-miR-16-5p Ccnd1
Northern blot [1]
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [2] [1]
mmu-miR-16-5p Bcl2
Northern blot [1]
qRT-PCR [1] [3]
Western blot [1] [3]
Luciferase reporter assay [1]
Flow cytometry [3]
mmu-miR-16-5p Arl2
qRT-PCR [4]
Western blot [4]
Luciferase reporter assay [4]
mmu-miR-16-5p Cadm1
Luciferase reporter assay [5]
mmu-miR-16-5p App
qRT-PCR [6]
In situ hybridization [6]
Western blot [6]
Luciferase reporter assay [6]
Immunohistochemistry [6]
mmu-miR-16-5p Mdm4
Northern blot [7]
qRT-PCR [7]
In situ hybridization [7]
GFP reporter assay [7]
Western blot [7]
mmu-miR-16-5p Jun
Northern blot [7]
qRT-PCR [7]
In situ hybridization [7]
GFP reporter assay [7]
Western blot [7]
mmu-miR-16-5p Jag1
Northern blot [7]
qRT-PCR [7]
In situ hybridization [7]
GFP reporter assay [7]
Western blot [7]
mmu-miR-16-5p Slc6a4
Luciferase reporter assay [8]
mmu-miR-16-5p Ccne1
qRT-PCR [3]
Western blot [3]
Luciferase reporter assay [9]
Flow cytometry [3]
mmu-miR-16-5p Bcl2l2
Western blot [10]
mmu-miR-16-5p Cd40
qRT-PCR [11]
microarray [11]
Western blot [11]
mmu-miR-16-5p Fgf2
qRT-PCR [11]
microarray [11]
Western blot [11]
mmu-miR-16-5p Rnf168
HITS-CLIP [12]
mmu-miR-16-5p Irgq
HITS-CLIP [12] [13] [14] [15] [16]
mmu-miR-16-5p Dhdh
HITS-CLIP [12] [15]
mmu-miR-16-5p Erlin2
HITS-CLIP [12]
mmu-miR-16-5p Creb5
HITS-CLIP [12]
mmu-miR-16-5p Klc1
HITS-CLIP [14] [15]
mmu-miR-16-5p Ddx19b
HITS-CLIP [14]
mmu-miR-16-5p Sorcs2
HITS-CLIP [14]
mmu-miR-16-5p Mapkap1
HITS-CLIP [14] [15]
mmu-miR-16-5p Armcx6
HITS-CLIP [14] [15]
mmu-miR-16-5p Angel1
HITS-CLIP [14]
mmu-miR-16-5p Pomk
HITS-CLIP [14]
mmu-miR-16-5p Tacc1
HITS-CLIP [14] [15]
mmu-miR-16-5p Spsb4
HITS-CLIP [14]
mmu-miR-16-5p Itgav
HITS-CLIP [14]
mmu-miR-16-5p Fbxo21
HITS-CLIP [14] [15]
mmu-miR-16-5p Bicd1
HITS-CLIP [14] [15] [16]
mmu-miR-16-5p Pacsin2
HITS-CLIP [15]
mmu-miR-16-5p Ncl
HITS-CLIP [15]
mmu-miR-16-5p Idua
HITS-CLIP [15]
mmu-miR-16-5p Fgd4
HITS-CLIP [15]
mmu-miR-16-5p Trim2
HITS-CLIP [15]
mmu-miR-16-5p Tifab
HITS-CLIP [15]
mmu-miR-16-5p Bri3bp
HITS-CLIP [15]
mmu-miR-16-5p Bcl11b
HITS-CLIP [15]
mmu-miR-16-5p Lpcat2b
HITS-CLIP [15]

References

authors journal year Pubmed link title
1 Bonci et al. Nat. Med. 2008 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities.
2 Salerno et al. Mol. Cancer Ther. 2009 19723889 Correcting miR-15a/16 genetic defect in New Zealand Black mouse model of CLL enhances drug sensitivity.
3 Rouse et al. J. Pharmacol. Exp. Ther. 2014 24898268 3,3'-diindolylmethane ameliorates experimental autoimmune encephalomyelitis by promoting cell cycle arrest and apoptosis in activated T cells through microRNA signaling pathways.
4 Nishi et al. J. Biol. Chem. 2010 20007690 MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via Arl2 in neonatal rat cardiac myocytes.
5 Calin et al. Proc. Natl. Acad. Sci. U.S.A. 2008 18362358 MiR-15a and miR-16-1 cluster functions in human leukemia.
6 Liu et al. Neurobiol. Aging 2012 20619502 MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice.
7 Gatt et al. Blood 2010 20962322 MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma.
8 Baudry et al. Science 2010 20847275 miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants.
9 Rivas et al. Breast Cancer Res. 2012 22583478 Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development.
10 Yu et al. Int. J. Biochem. Cell Biol. 2013 24070634 Enhanced mesenchymal stem cell survival induced by GATA-4 overexpression is partially mediated by regulation of the miR-15 family.
11 Cuevas et al. Arch. Biochem. Biophys. 2014 24792245 Identification of microRNAs involved in the modulation of pro-angiogenic factors in atherosclerosis by a polyphenol-rich extract from propolis.
12 Zhang et al. Cell 2014 25083871 MicroRNA directly enhances mitochondrial translation during muscle differentiation.
13 Loeb et al. Mol. Cell 2012 23142080 Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting.
14 Schug et al. BMC Genomics 2013 23597149 Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver.
15 Leung et al. Nat. Struct. Mol. Biol. 2011 21258322 Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs.
16 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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