Targets miRBase

mmu-let-7a-5p (MIMAT0000521) (21 targets) in miRTarBase

miRNA gene name experiments
mmu-let-7a-5p Hoxa9
Western blot [1]
FACS [1]
mmu-let-7a-5p Hmga2
Luciferase reporter assay [2]
mmu-let-7a-5p Il13
qRT-PCR [3]
microarray [3]
NGS [3]
Luciferase reporter assay [3]
mmu-let-7a-5p Trim71
Northern blot [4]
qRT-PCR [4]
In situ hybridization [4]
GFP reporter assay [4]
Western blot [4]
Immunocytochemistry [4]
Immunoprecipitaion [4]
Flow cytometry [4]
Immunohistochemistry [4]
mmu-let-7a-5p Lin28a
qRT-PCR [5]
B-globin reporter assay [6]
mmu-let-7a-5p Nf2
HITS-CLIP [7] [8]
mmu-let-7a-5p Gnl3l
HITS-CLIP [9] [7]
mmu-let-7a-5p Cts8
HITS-CLIP [7] [9]
mmu-let-7a-5p Apc2
HITS-CLIP [7] [10] [9]
mmu-let-7a-5p Msi2
HITS-CLIP [7]
mmu-let-7a-5p Fbxl14
HITS-CLIP [7]
mmu-let-7a-5p Lins1
HITS-CLIP [7]
mmu-let-7a-5p Mup17
HITS-CLIP [8]
mmu-let-7a-5p Mup11
HITS-CLIP [8]
mmu-let-7a-5p Armc2
HITS-CLIP [8] [9]
mmu-let-7a-5p Meis2
HITS-CLIP [10]
mmu-let-7a-5p Zfp444
HITS-CLIP [9]
mmu-let-7a-5p Nup214
HITS-CLIP [9]
mmu-let-7a-5p Atp2b2
HITS-CLIP [9]
mmu-let-7a-5p Tnfrsf26
HITS-CLIP [9]
mmu-let-7a-5p Ifnar1
HITS-CLIP [9]

References

authors journal year Pubmed link title
1 Shen et al. Mol. Cell. Biol. 2008 18474618 MicroRNA-126 regulates HOXA9 by binding to the homeobox.
2 Mayr et al. Science 2007 17322030 Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation.
3 Polikepahad et al. J. Biol. Chem. 2010 20630862 Proinflammatory role for let-7 microRNAS in experimental asthma.
4 Rybak et al. Nat. Cell Biol. 2009 19898466 The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2.
5 Madison et al. Genes Dev. 2013 24142874 LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7.
6 Wu et al. Proc. Natl. Acad. Sci. U.S.A. 2006 16495412 MicroRNAs direct rapid deadenylation of mRNA.
7 Zhang et al. Cell 2014 25083871 MicroRNA directly enhances mitochondrial translation during muscle differentiation.
8 Schug et al. BMC Genomics 2013 23597149 Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver.
9 Leung et al. Nat. Struct. Mol. Biol. 2011 21258322 Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs.
10 Loeb et al. Mol. Cell 2012 23142080 Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting.