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hsa-miR-206 (MIMAT0000462) (91 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-206 MET
Northern blot [1]
qRT-PCR [1]
ChIP [1]
Western blot [2] [3] [1]
Luciferase reporter assay [3] [1]
hsa-miR-206 NOTCH3
qRT-PCR [4]
Reporter assay [4]
Western blot [4]
Luciferase reporter assay [4]
hsa-miR-206 UTRN
Reporter assay [5]
hsa-miR-206 FSTL1
Reporter assay [5]
hsa-miR-206 TAC1
Reporter assay [6]
Other [6]
Luciferase reporter assay [6]
hsa-miR-206 PAX3
qRT-PCR [7] [8] [9]
ChIP [9]
Immunofluorescence [8]
Western blot [9] [7] [8]
Immunoblot [9]
Luciferase reporter assay [7] [8] [9]
Immunohistochemistry [8]
hsa-miR-206 CCND2
Luciferase reporter assay [10] [11]
hsa-miR-206 GJA1
Western blot [12]
hsa-miR-206 CDK4
microarray [13]
Luciferase reporter assay [13]
hsa-miR-206 ACTL6A
Western blot [14]
Luciferase reporter assay [14]
hsa-miR-206 NR1H3
qRT-PCR [15]
Western blot [15]
Luciferase reporter assay [15]
hsa-miR-206 FNDC3A
PAR-CLIP [16]
hsa-miR-206 KLF13
PAR-CLIP [17]
hsa-miR-206 RNF138
PAR-CLIP [17]
hsa-miR-206 BCL2
qRT-PCR [18]
Flow cytometry [18]
hsa-miR-206 C5orf51
HITS-CLIP [19]
PAR-CLIP [17]
hsa-miR-206 WEE1
PAR-CLIP [16]
hsa-miR-206 KCNJ2
PAR-CLIP [20]
hsa-miR-206 NUP50
PAR-CLIP [21] [20] [17]
hsa-miR-206 QSER1
PAR-CLIP [20]
hsa-miR-206 ANP32B
HITS-CLIP [19]
hsa-miR-206 PPP2R1B
PAR-CLIP [16]
hsa-miR-206 GPD2
Western blot [22]
Luciferase reporter assay [22]
Quantitative proteomic approach [22]
hsa-miR-206 TKT
Western blot [22]
Luciferase reporter assay [22]
Quantitative proteomic approach [22]
hsa-miR-206 PGD
Western blot [22]
Luciferase reporter assay [22]
Quantitative proteomic approach [22]
hsa-miR-206 G6PD
Western blot [22]
Luciferase reporter assay [22]
Quantitative proteomic approach [22]
hsa-miR-206 VAMP2
Luciferase reporter assay [23]
hsa-miR-206 SMARCB1
qRT-PCR [24]
Immunohistochemistry [24]
hsa-miR-206 KRAS
qRT-PCR [18] [25]
Western blot [25]
Luciferase reporter assay [25]
Flow cytometry [18]
hsa-miR-206 BDNF
qRT-PCR [18]
Flow cytometry [18]
hsa-miR-206 SFRP1
qRT-PCR [18]
Flow cytometry [18]
hsa-miR-206 FRS2
qRT-PCR [18]
Flow cytometry [18]
hsa-miR-206 IGF1R
qRT-PCR [18]
Flow cytometry [18]
hsa-miR-206 KLF4
qRT-PCR [18]
Flow cytometry [18]
hsa-miR-206 HDAC4
qRT-PCR [18]
Flow cytometry [18]
hsa-miR-206 STC2
qRT-PCR [18]
hsa-miR-206 CCND1
Western blot [26]
Luciferase reporter assay [27] [26]
hsa-miR-206 C8A
PAR-CLIP [28]
hsa-miR-206 C17orf102
PAR-CLIP [28]
hsa-miR-206 RIMS4
PAR-CLIP [28]
hsa-miR-206 FGD4
PAR-CLIP [28]
hsa-miR-206 TOX4
PAR-CLIP [28]
hsa-miR-206 STAMBP
PAR-CLIP [28]
hsa-miR-206 NT5C1B
PAR-CLIP [16]
hsa-miR-206 NT5C1B-RDH14
PAR-CLIP [16]
hsa-miR-206 PSMA7
PAR-CLIP [16]
hsa-miR-206 CHML
PAR-CLIP [16]
hsa-miR-206 SALL2
PAR-CLIP [16]
hsa-miR-206 MRPS27
PAR-CLIP [16]
hsa-miR-206 WBP2
PAR-CLIP [16]
hsa-miR-206 STX6
PAR-CLIP [16]
hsa-miR-206 RGP1
PAR-CLIP [16]
hsa-miR-206 TSPAN1
PAR-CLIP [16]
hsa-miR-206 MATR3
PAR-CLIP [16]
hsa-miR-206 H3F3C
PAR-CLIP [21] [20] [17] [16]
hsa-miR-206 EIF1AX
PAR-CLIP [16]
hsa-miR-206 DDX19B
PAR-CLIP [16]
hsa-miR-206 CERS2
PAR-CLIP [16]
hsa-miR-206 BSCL2
PAR-CLIP [16]
hsa-miR-206 SMKR1
PAR-CLIP [20] [16] [21]
hsa-miR-206 ANK1
PAR-CLIP [16]
hsa-miR-206 RAB5C
PAR-CLIP [21] [20] [17] [16]
hsa-miR-206 NFAT5
PAR-CLIP [21] [20] [17] [16]
hsa-miR-206 CALM2
PAR-CLIP [16]
hsa-miR-206 H3F3B
PAR-CLIP [21] [16]
hsa-miR-206 MYEF2
PAR-CLIP [29]
hsa-miR-206 PTMA
HITS-CLIP [17]
PAR-CLIP [21] [20] [17] [30]
hsa-miR-206 CRK
PAR-CLIP [21] [20]
hsa-miR-206 ARPP19
PAR-CLIP [21] [20]
hsa-miR-206 ZCCHC3
PAR-CLIP [21]
hsa-miR-206 HSP90B1
PAR-CLIP [21] [20]
hsa-miR-206 TFAM
PAR-CLIP [31]
hsa-miR-206 VSTM5
PAR-CLIP [31]
hsa-miR-206 SULT1B1
PAR-CLIP [31]
hsa-miR-206 NUDT21
PAR-CLIP [31]
hsa-miR-206 SERP1
PAR-CLIP [17]
hsa-miR-206 HNRNPA1
PAR-CLIP [17]
hsa-miR-206 LRRC59
PAR-CLIP [20]
hsa-miR-206 ZNF215
PAR-CLIP [20]
hsa-miR-206 ZBED3
PAR-CLIP [20]
hsa-miR-206 ANP32E
PAR-CLIP [20]
hsa-miR-206 FAM216B
HITS-CLIP [32]
hsa-miR-206 ATP5E
HITS-CLIP [32]
hsa-miR-206 FYB1
HITS-CLIP [32]
hsa-miR-206 PLAGL2
HITS-CLIP [19]
hsa-miR-206 ZNF185
HITS-CLIP [19]
hsa-miR-206 ALPI
HITS-CLIP [19]
hsa-miR-206 TM4SF1
HITS-CLIP [19]
hsa-miR-206 STX12
HITS-CLIP [19]
hsa-miR-206 ZNF79
HITS-CLIP [33]
hsa-miR-206 SPTLC3
HITS-CLIP [33]

References

authors journal year Pubmed link title
1 Di Leva et al. J. Natl. Cancer Inst. 2010 20388878 MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer.
2 Taulli et al. J. Clin. Invest. 2009 19620785 The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation.
3 Yan et al. J. Biol. Chem. 2009 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development.
4 Song et al. J. Biol. Chem. 2009 19723635 MicroRNA-206 targets notch3, activates apoptosis, and inhibits tumor cell migration and focus formation.
5 Rosenberg et al. J. Cell Biol. 2006 17030984 MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206.
6 Greco et al. Proc. Natl. Acad. Sci. U.S.A. 2007 17855557 MicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells.
7 Boutet et al. Cell Stem Cell 2012 22385659 Alternative polyadenylation mediates microRNA regulation of muscle stem cell function.
8 Zhang et al. Carcinogenesis 2015 25653235 Activation of PAX3-MET pathways due to miR-206 loss promotes gastric cancer metastasis.
9 Hirai et al. J. Cell Biol. 2010 20956382 MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3.
10 Zhang et al. Cancer Lett. 2013 23348698 miR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2.
11 Zhou et al. Biochem. Biophys. Res. Commun. 2013 23466356 miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2.
12 Anderson et al. Nucleic Acids Res. 2006 17062625 MIR-206 regulates connexin43 expression during skeletal muscle development.
13 Georgantas et al. Pigment Cell Melanoma Res 2014 24289491 MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D.
14 Taulli et al. Oncogene 2014 23728344 Failure to downregulate the BAF53a subunit of the SWI/SNF chromatin remodeling complex contributes to the differentiation block in rhabdomyosarcoma.
15 Vinod et al. Biochim. Biophys. Acta 2014 24603323 miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages.
16 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
17 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
18 Ren et al. Cell Biosci 2014 24855559 MicroRNA-206 suppresses gastric cancer cell growth and metastasis.
19 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
20 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
21 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
22 Singh et al. J. Clin. Invest. 2013 23921124 Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis.
23 Zhang et al. FEBS Lett. 2015 25481410 MicroRNA-206 regulates surfactant secretion by targeting VAMP-2.
24 Papp et al. Genes Chromosomes Cancer 2014 24327545 SMARCB1 expression in epithelioid sarcoma is regulated by miR-206, miR-381, and miR-671-5p on Both mRNA and protein levels.
25 Lin et al. Onco Targets Ther 2014 25246801 MiR-206 functions as a tumor suppressor and directly targets K-Ras in human oral squamous cell carcinoma.
26 Elliman et al. Oncogenesis 2014 25111862 Selective repression of the oncogene cyclin D1 by the tumor suppressor miR-206 in cancers.
27 Alteri et al. Cell Cycle 2013 24107628 Cyclin D1 is a major target of miR-206 in cell differentiation and transformation.
28 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
29 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
30 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
31 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
32 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
33 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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