Targets miRBase

hsa-miR-195-5p (MIMAT0000461) (605 targets) in miRTarBase

References

authors journal year Pubmed link title
1 Bhattacharya et al. Oncogene 2013 22847610 Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma.
2 Qi et al. Cell Cycle 2009 19823043 microRNAs regulate human embryonic stem cell division.
3 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
4 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
5 Xu et al. Hepatology 2009 19441017 MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells.
6 Zhang et al. Neuro-oncology 2012 22217655 MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion.
7 Riley et al. EMBO J. 2012 22473208 EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency.
8 Deng et al. Gene 2013 23333942 MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigenetical regulation in gastric cancer.
9 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
10 Jia et al. PLoS ONE 2013 23451060 Prognostic implications of micoRNA miR-195 expression in human tongue squamous cell carcinoma.
11 Luo et al. Oncol. Rep. 2014 24402230 MicroRNA-195-5p is a potential diagnostic and therapeutic target for breast cancer.
12 Hui et al. PLoS ONE 2013 23383003 MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1.
13 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
14 Murakami et al. Oncogene 2006 16331254 Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues.
15 Ye et al. PLoS ONE 2008 18320040 The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.
16 Wang et al. Hepatology 2013 23468064 MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42.
17 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
18 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
19 Gonsalves et al. J. Immunol. 2010 20952681 Endothelin-1-induced macrophage inflammatory protein-1beta expression in monocytic cells involves hypoxia-inducible factor-1alpha and AP-1 and is negatively regulated by microRNA-195.
20 Liu et al. Biochem. Biophys. Res. Commun. 2010 20727858 microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells.
21 Li et al. Clin. Cancer Res. 2011 21350001 Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer.
22 Yang et al. Oncol. Rep. 2013 23760062 Upregulation of miR-195 increases the sensitivity of breast cancer cells to Adriamycin treatment through inhibition of Raf-1.
23 Fei et al. FEBS Lett. 2012 22265971 MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression.
24 Furuta et al. PLoS ONE 2013 23544130 The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma.
25 Lin et al. FEBS Lett. 2012 22289176 Cyclin-dependent kinase 4 is a novel target in micoRNA-195-mediated cell cycle arrest in bladder cancer cells.
26 Fu et al. FEBS Lett. 2013 24025765 Differential expression of miR-195 in esophageal squamous cell carcinoma and miR-195 expression inhibits tumor cell proliferation and invasion by targeting of Cdc42.
27 Wang et al. Cardiovasc. Res. 2012 22802111 MicroRNA-195 regulates vascular smooth muscle cell phenotype and prevents neointimal formation.
28 Chen et al. PLoS ONE 2012 22844503 Micro-RNA-195 and -451 regulate the LKB1/AMPK signaling axis by targeting MO25.
29 Ding et al. Hepatology 2013 23487264 Genome-wide screening reveals that miR-195 targets the TNF-α/NF-κB pathway by down-regulating IκB kinase alpha and TAB3 in hepatocellular carcinoma.
30 Liu et al. PLoS ONE 2013 23349673 An epigenetic feedback regulatory loop involving microRNA-195 and MBD1 governs neural stem cell differentiation.
31 Qu et al. J. Cell. Physiol. 2015 23526568 MicroRNA-195 chemosensitizes colon cancer cells to the chemotherapeutic drug doxorubicin by targeting the first binding site of BCL2L2 mRNA.
32 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
33 Caramuta et al. Endocr. Relat. Cancer 2013 23671264 Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma.
34 Mao et al. Oncol Lett 2012 23162665 microRNA-195 suppresses osteosarcoma cell invasion and migration in vitro by targeting FASN.
35 Zhou et al. Cell Death Dis 2013 23807224 MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells.
36 Itesako et al. PLoS ONE 2014 24520312 The microRNA expression signature of bladder cancer by deep sequencing: the functional significance of the miR-195/497 cluster.
37 Yongchun et al. Cancer Lett. 2014 24486218 MicroRNA-195 inhibits non-small cell lung cancer cell proliferation, migration and invasion by targeting MYB.
38 Shi et al. Glia 2013 23361941 Increased miR-195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury.
39 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
40 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
41 Majoros et al. Nat. Methods 2013 23708386 MicroRNA target site identification by integrating sequence and binding information.
42 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
43 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
44 Pillai et al. Breast Cancer Res. Treat. 2014 24906430 HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.
45 Lu et al. PLoS ONE 2012 22815788 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.
46 Yang et al. FEBS Lett. 2014 25240198 Saturated fatty acid-induced miR-195 impairs insulin signaling and glycogen metabolism in HepG2 cells.
47 Zampetaki et al. Circ. Res. 2014 25201911 Role of miR-195 in aortic aneurysmal disease.
48 Díaz-Beyá et al. Leukemia 2013 23022987 Acute myeloid leukemia with translocation (8;16)(p11;p13) and MYST3-CREBBP rearrangement harbors a distinctive microRNA signature targeting RET proto-oncogene.
49 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
50 Haecker et al. PLoS Pathog. 2012 22927820 Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas.
51 Kishore et al. Genome Biol. 2013 23706177 Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing.
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