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hsa-miR-146a-5p (MIMAT0000449) (164 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-146a-5p CXCR4
qRT-PCR [1]
microarray [2]
Western blot [1]
Luciferase reporter assay [1]
hsa-miR-146a-5p CFH
Western blot [3] [4]
hsa-miR-146a-5p IRAK2
qRT-PCR [5]
Western blot [5]
hsa-miR-146a-5p TLR2
qRT-PCR [2]
Western blot [2]
Other [2]
Luciferase reporter assay [2]
Flow cytometry [2]
hsa-miR-146a-5p FADD
Luciferase reporter assay [6]
hsa-miR-146a-5p IRAK1
Northern blot [7] [8] [9]
qRT-PCR [10] [11] [7] [12] [8] [13] [14] [15] [16]
microarray [7] [17]
In situ hybridization [13]
Immunofluorescence [14]
Western blot [14] [15] [16] [18] [10] [19] [20] [17] [9] [12] [8] [13]
Luciferase reporter assay [21] [10] [18] [22] [7] [20] [8] [13]
ELISA [8]
hsa-miR-146a-5p ROCK1
Northern blot [23]
Western blot [23]
Luciferase reporter assay [23]
Flow cytometry [23]
hsa-miR-146a-5p BRCA2
Luciferase reporter assay [24]
hsa-miR-146a-5p BRCA1
qRT-PCR [25]
microarray [25]
ChIP [26]
Western blot [25]
Luciferase reporter assay [24] [26]
hsa-miR-146a-5p FAF1
qRT-PCR [27]
GFP reporter assay [27]
hsa-miR-146a-5p CCNA2
qRT-PCR [25]
microarray [25]
Western blot [25]
hsa-miR-146a-5p PA2G4
qRT-PCR [25]
microarray [25]
Western blot [25]
hsa-miR-146a-5p CXCL8
Northern blot [9]
microarray [5]
Western blot [9]
hsa-miR-146a-5p NFKB1
qRT-PCR [28] [5]
microarray [24]
Western blot [28] [5]
Luciferase reporter assay [9] [28]
Flow cytometry [28]
hsa-miR-146a-5p EGFR
qRT-PCR [29] [30] [5] [31]
Western blot [32] [29] [30] [5] [31] [20]
Luciferase reporter assay [29] [31] [20]
hsa-miR-146a-5p MTA2
qRT-PCR [5]
Western blot [5]
hsa-miR-146a-5p CD40LG
qRT-PCR [33]
Western blot [33]
Luciferase reporter assay [33]
ELISA [33]
hsa-miR-146a-5p FAS
Western blot [34]
Luciferase reporter assay [34] [35]
hsa-miR-146a-5p ERBB4
Northern blot [36]
microarray [37]
Western blot [37]
Luciferase reporter assay [37] [36]
hsa-miR-146a-5p SMAD4
qRT-PCR [38] [39] [40] [41] [42]
microarray [40] [38]
Western blot [38] [39] [40] [41] [42]
Luciferase reporter assay [39] [40] [41] [42] [38]
Immunohistochemistry [40] [38]
hsa-miR-146a-5p TLR4
qRT-PCR [43]
microarray [43]
Western blot [43]
Luciferase reporter assay [43]
ELISA [43]
hsa-miR-146a-5p WASF2
Luciferase reporter assay [44]
hsa-miR-146a-5p IRF7
microarray [45]
hsa-miR-146a-5p PPP1R1C
microarray [45]
hsa-miR-146a-5p ITGB2
microarray [45]
hsa-miR-146a-5p SNTG2
microarray [45]
hsa-miR-146a-5p RSAD2
microarray [45]
hsa-miR-146a-5p BGLAP
qRT-PCR [19]
hsa-miR-146a-5p SYT12
microarray [45]
hsa-miR-146a-5p STAT1
qRT-PCR [46]
microarray [19]
Western blot [46]
Other [47]
Luciferase reporter assay [46]
hsa-miR-146a-5p IFIT1
microarray [45]
hsa-miR-146a-5p IFITM1
microarray [45]
hsa-miR-146a-5p OLFML2A
microarray [45]
hsa-miR-146a-5p ISG15
microarray [45]
hsa-miR-146a-5p UHRF1
microarray [48]
Western blot [48]
Luciferase reporter assay [48]
Immunohistochemistry [48]
hsa-miR-146a-5p IFITM3
microarray [45]
hsa-miR-146a-5p RGS13
microarray [45]
hsa-miR-146a-5p MTUS2
microarray [45]
hsa-miR-146a-5p NMI
microarray [45]
hsa-miR-146a-5p HSPA1A
microarray [45]
hsa-miR-146a-5p TRIM22
microarray [45]
hsa-miR-146a-5p ITGBL1
microarray [45]
hsa-miR-146a-5p SPATS2L
microarray [45]
hsa-miR-146a-5p IFI44
microarray [45]
hsa-miR-146a-5p OASL
microarray [45]
hsa-miR-146a-5p IFI44L
microarray [45]
hsa-miR-146a-5p IFI27
microarray [45]
hsa-miR-146a-5p METTL7A
PAR-CLIP [49]
hsa-miR-146a-5p LINC00304
microarray [45]
hsa-miR-146a-5p STON2
microarray [45]
hsa-miR-146a-5p BCL2A1
microarray [45]
hsa-miR-146a-5p MX2
microarray [45]
hsa-miR-146a-5p EPSTI1
microarray [45]
hsa-miR-146a-5p OSBPL1A
microarray [45]
hsa-miR-146a-5p IFIT5
microarray [45]
hsa-miR-146a-5p C1orf21
microarray [45]
hsa-miR-146a-5p GIMAP4
microarray [45]
hsa-miR-146a-5p CCR9
microarray [45]
hsa-miR-146a-5p SAMD9L
microarray [45]
hsa-miR-146a-5p IFIT3
microarray [45]
hsa-miR-146a-5p SPP1
qRT-PCR [19]
hsa-miR-146a-5p SLPI
qRT-PCR [19]
Western blot [19]
hsa-miR-146a-5p L1CAM
Luciferase reporter assay [50]
hsa-miR-146a-5p MSC
CLASH [51]
hsa-miR-146a-5p SMN1
qRT-PCR [41]
Western blot [41]
Luciferase reporter assay [41]
Caspase-Glo® 3/7 assay [41]
Cell proliferation assay [41]
hsa-miR-146a-5p CARD10
qRT-PCR [52] [13]
In situ hybridization [13]
Western blot [52] [13]
Luciferase reporter assay [52] [13]
hsa-miR-146a-5p COPS8
qRT-PCR [13]
In situ hybridization [13]
Western blot [13]
Luciferase reporter assay [13]
hsa-miR-146a-5p ELAVL1
qRT-PCR [53]
Western blot [53]
Luciferase reporter assay [53]
Immunoprecipitation [53]
hsa-miR-146a-5p NUMB
qRT-PCR [54]
Western blot [54]
Luciferase reporter assay [55]
hsa-miR-146a-5p ICAM1
qRT-PCR [12]
Western blot [12]
hsa-miR-146a-5p SMAD2
qRT-PCR [56]
Western blot [56]
hsa-miR-146a-5p KCTD15
PAR-CLIP [57] [58] [59] [60]
hsa-miR-146a-5p ARL8A
PAR-CLIP [60]
hsa-miR-146a-5p SQSTM1
PAR-CLIP [60] [61]
hsa-miR-146a-5p PMAIP1
PAR-CLIP [60]
hsa-miR-146a-5p PTGS2
qRT-PCR [62]
Western blot [62]
Luciferase reporter assay [62]
Flow cytometry [62]
hsa-miR-146a-5p CCL5
Luciferase reporter assay [63]
hsa-miR-146a-5p S100A12
qRT-PCR [64]
microarray [64]
hsa-miR-146a-5p ZNF117
qRT-PCR [64]
microarray [64]
hsa-miR-146a-5p MYO6
qRT-PCR [64]
microarray [64]
hsa-miR-146a-5p CCDC6
qRT-PCR [64]
microarray [64]
hsa-miR-146a-5p IL1RAP
qRT-PCR [64]
microarray [64]
hsa-miR-146a-5p IL1RL2
qRT-PCR [64]
microarray [64]
hsa-miR-146a-5p ROBO1
qRT-PCR [65]
hsa-miR-146a-5p PTGES2
Luciferase reporter assay [66]
hsa-miR-146a-5p CNOT6L
Luciferase reporter assay [67]
hsa-miR-146a-5p SIKE1
qRT-PCR [68]
microarray [68]
Luciferase reporter assay [68]
hsa-miR-146a-5p CXCL12
qRT-PCR [68]
microarray [68]
Luciferase reporter assay [68]
hsa-miR-146a-5p PRKCE
Luciferase reporter assay [69]
hsa-miR-146a-5p HOXD10
qRT-PCR [70]
Western blot [70]
Immunohistochemistry [70]
hsa-miR-146a-5p RAC1
qRT-PCR [71]
In situ hybridization [71]
Western blot [71]
Luciferase reporter assay [71]
hsa-miR-146a-5p LAMC2
qRT-PCR [71]
In situ hybridization [71]
Western blot [71]
Luciferase reporter assay [71]
hsa-miR-146a-5p COX2
qRT-PCR [72]
Luciferase reporter assay [72]
hsa-miR-146a-5p DUSP1
qRT-PCR [73]
Western blot [73]
hsa-miR-146a-5p RNF11
Luciferase reporter assay [74]
hsa-miR-146a-5p SERPINA4
PAR-CLIP [49]
hsa-miR-146a-5p ESD
PAR-CLIP [49]
hsa-miR-146a-5p ST6GAL2
PAR-CLIP [49]
hsa-miR-146a-5p SFRP1
PAR-CLIP [49]
hsa-miR-146a-5p MKRN2
PAR-CLIP [49]
hsa-miR-146a-5p PARD6B
PAR-CLIP [49]
hsa-miR-146a-5p ACTBL2
PAR-CLIP [49]
hsa-miR-146a-5p LIMD2
PAR-CLIP [49]
hsa-miR-146a-5p TMPRSS5
PAR-CLIP [57]
hsa-miR-146a-5p HAAO
PAR-CLIP [57]
hsa-miR-146a-5p TMEM214
PAR-CLIP [57]
hsa-miR-146a-5p BCL7B
PAR-CLIP [57]
hsa-miR-146a-5p SRPRB
PAR-CLIP [59] [60] [57]
hsa-miR-146a-5p SHCBP1
PAR-CLIP [57]
hsa-miR-146a-5p RHOBTB3
PAR-CLIP [57]
hsa-miR-146a-5p RAB2B
PAR-CLIP [57]
hsa-miR-146a-5p PPP1R11
PAR-CLIP [57]
hsa-miR-146a-5p NACC1
PAR-CLIP [57]
hsa-miR-146a-5p ATG9A
PAR-CLIP [57]
hsa-miR-146a-5p GXYLT2
PAR-CLIP [57]
hsa-miR-146a-5p MICAL2
PAR-CLIP [59] [57]
hsa-miR-146a-5p COPA
PAR-CLIP [57]
hsa-miR-146a-5p GRAP2
PAR-CLIP [57]
hsa-miR-146a-5p CD300LB
PAR-CLIP [75]
hsa-miR-146a-5p MBD4
PAR-CLIP [60] [61]
hsa-miR-146a-5p PPWD1
PAR-CLIP [58] [59] [76]
hsa-miR-146a-5p TMEM136
PAR-CLIP [58]
hsa-miR-146a-5p ZNF292
PAR-CLIP [76]
hsa-miR-146a-5p USP48
PAR-CLIP [76]
hsa-miR-146a-5p PLEKHG5
PAR-CLIP [76]
hsa-miR-146a-5p CCDC83
PAR-CLIP [60]
hsa-miR-146a-5p DECR1
PAR-CLIP [60]
hsa-miR-146a-5p TMEM101
PAR-CLIP [60]
hsa-miR-146a-5p ZNF260
PAR-CLIP [60]
hsa-miR-146a-5p AKAP8
PAR-CLIP [59] [60]
hsa-miR-146a-5p TMEM167A
PAR-CLIP [59] [60]
hsa-miR-146a-5p RUFY2
PAR-CLIP [60]
hsa-miR-146a-5p C16orf52
PAR-CLIP [60]
hsa-miR-146a-5p ATP13A3
PAR-CLIP [60]
hsa-miR-146a-5p SERTAD2
PAR-CLIP [59]
hsa-miR-146a-5p LBR
PAR-CLIP [59]
hsa-miR-146a-5p FANCF
PAR-CLIP [59]
hsa-miR-146a-5p LSM4
PAR-CLIP [59]
hsa-miR-146a-5p BTN2A2
PAR-CLIP [59]
hsa-miR-146a-5p SERBP1
PAR-CLIP [59]
hsa-miR-146a-5p GPM6B
HITS-CLIP [77]
hsa-miR-146a-5p ELP2
HITS-CLIP [77]
hsa-miR-146a-5p ZNF629
HITS-CLIP [77]
hsa-miR-146a-5p MDN1
HITS-CLIP [77]
hsa-miR-146a-5p POU3F1
HITS-CLIP [77]
hsa-miR-146a-5p TLL1
HITS-CLIP [77]
hsa-miR-146a-5p HORMAD2
HITS-CLIP [77]
hsa-miR-146a-5p MFSD6
HITS-CLIP [77]
hsa-miR-146a-5p ENTPD5
HITS-CLIP [77]
hsa-miR-146a-5p UTP15
HITS-CLIP [77]
hsa-miR-146a-5p CYTIP
HITS-CLIP [77] [78]
hsa-miR-146a-5p ZNF738
HITS-CLIP [78]
hsa-miR-146a-5p UMPS
HITS-CLIP [79]
hsa-miR-146a-5p MRPS30
HITS-CLIP [79]
hsa-miR-146a-5p MRPL10
HITS-CLIP [79]
hsa-miR-146a-5p RGS9BP
HITS-CLIP [79]
hsa-miR-146a-5p ALG10B
HITS-CLIP [79]
hsa-miR-146a-5p PACS2
HITS-CLIP [79]
hsa-miR-146a-5p EDEM3
HITS-CLIP [79]
hsa-miR-146a-5p CDC73
HITS-CLIP [79]
hsa-miR-146a-5p AVL9
HITS-CLIP [79]
hsa-miR-146a-5p CYBRD1
HITS-CLIP [80]
hsa-miR-146a-5p MYLK
HITS-CLIP [80]
hsa-miR-146a-5p DGCR6L
HITS-CLIP [80]

References

authors journal year Pubmed link title
1 Labbaye et al. Nat. Cell Biol. 2008 18568019 A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis.
2 Jurkin et al. J. Immunol. 2010 20375304 miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation.
3 Lukiw et al. J. Biol. Chem. 2008 18801740 An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells.
4 Pogue et al. J. Inorg. Biochem. 2009 19540598 Characterization of an NF-kappaB-regulated, miRNA-146a-mediated down-regulation of complement factor H (CFH) in metal-sulfate-stressed human brain cells.
5 Li et al. Cancer Res. 2010 20124483 miR-146a suppresses invasion of pancreatic cancer cells.
6 Curtale et al. Blood 2010 19965651 An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes.
7 Taganov et al. Proc. Natl. Acad. Sci. U.S.A. 2006 16885212 NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses.
8 Liu et al. Microbes Infect. 2010 20542134 Up-regulated microRNA-146a negatively modulate Helicobacter pylori-induced inflammatory response in human gastric epithelial cells.
9 Bhaumik et al. Oncogene 2008 18504431 Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells.
10 Xie et al. J Inflamm (Lond) 2013 23680172 MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts.
11 Pauley et al. Arthritis Res. Ther. 2008 18759964 Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients.
12 Wang et al. Invest. Ophthalmol. Vis. Sci. 2014 24867582 Regulation of retinal inflammation by rhythmic expression of MiR-146a in diabetic retina.
13 Crone et al. Mol. Cancer 2012 22992343 microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer.
14 Pauley et al. Immunol. Cell Biol. 2010 19918258 Formation of GW/P bodies as marker for microRNA-mediated regulation of innate immune signaling in THP-1 cells.
15 Nahid et al. J. Immunol. 2011 21178010 Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling.
16 Xia et al. Immunol. Lett. 2012 23018031 Dysregulation of miRNA146a versus IRAK1 induces IL-17 persistence in the psoriatic skin lesions.
17 Jayadev et al. J. Neurochem. 2013 23952003 Presenilin 2 influences miR146 level and activity in microglia.
18 Pacifico et al. J. Clin. Endocrinol. Metab. 2010 20061417 Nuclear factor-{kappa}B contributes to anaplastic thyroid carcinomas through up-regulation of miR-146a.
19 Hung et al. J. Dent. Res. 2010 20110513 miR-146a induces differentiation of periodontal ligament cells.
20 Kogo et al. Clin. Cancer Res. 2011 21632853 Clinical significance of miR-146a in gastric cancer cases.
21 Huang et al. FASEB J. 2012 22593544 miR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium.
22 Wang et al. Osteoarthr. Cartil. 2013 24107356 Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes.
23 Lin et al. RNA 2008 18174313 Loss of mir-146a function in hormone-refractory prostate cancer.
24 Shen et al. Carcinogenesis 2008 18660546 A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis.
25 Hsieh et al. Exp. Cell Res. 2010 19944095 Identification of the potential target genes of microRNA-146a induced by PMA treatment in human microvascular endothelial cells.
26 Zhu et al. Carcinogenesis 2013 23671131 MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression.
27 Li et al. Arthritis Res. Ther. 2010 20459811 Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis.
28 Sha et al. Cancer Cell Int. 2013 23706078 Celastrol induces apoptosis of gastric cancer cells by miR-146a inhibition of NF-κB activity.
29 Xu et al. Prostate 2012 22161865 MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer.
30 Chen et al. PLoS ONE 2013 23555954 miR-146a inhibits cell growth, cell migration and induces apoptosis in non-small cell lung cancer cells.
31 Ali et al. Cancer Lett. 2014 24839931 Deregulation of miR-146a expression in a mouse model of pancreatic cancer affecting EGFR signaling.
32 Hurst et al. Cancer Res. 2009 19190326 Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis.
33 Chen et al. FEBS Lett. 2011 21236257 MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells.
34 Suzuki et al. Am. J. Physiol. Heart Circ. Physiol. 2010 20656888 Diazoxide potentiates mesenchymal stem cell survival via NF-kappaB-dependent miR-146a expression by targeting Fas.
35 Guo et al. Blood 2013 23645835 Forced miR-146a expression causes autoimmune lymphoproliferative syndrome in mice via downregulation of Fas in germinal center B cells.
36 Halkein et al. J. Clin. Invest. 2013 23619365 MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy.
37 Barker et al. Curr Opin Pharmacol 2010 20864407 Regulation of ErbB receptor signalling in cancer cells by microRNA.
38 Li et al. Arthritis Res. Ther. 2012 22507670 miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4.
39 Liu et al. Arch. Dermatol. Res. 2012 21968601 MicroRNA-146a modulates TGF-β1-induced phenotypic differentiation in human dermal fibroblasts by targeting SMAD4.
40 Li et al. Tumour Biol. 2013 23832538 Differential miRNA profile on photoaged primary human fibroblasts irradiated with ultraviolet A.
41 Xiao et al. Oncol. Rep. 2012 22020746 Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis.
42 Jin et al. Int. J. Mol. Med. 2014 24939082 Role of miR-146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro.
43 Yang et al. FEBS Lett. 2011 21329689 MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4.
44 Yao et al. Cancer Lett. 2013 23435376 MicroRNA-146a acts as a metastasis suppressor in gastric cancer by targeting WASF2.
45 Cameron et al. J. Virol. 2008 18057241 Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathways.
46 Hou et al. Liver Int. 2014 23890093 miR146a impairs the IFN-induced anti-HBV immune response by downregulating STAT1 in hepatocytes.
47 Wang et al. J. Immunol. 2013 23698745 MicroRNA-146a feedback suppresses T cell immune function by targeting Stat1 in patients with chronic hepatitis B.
48 Zhou et al. FASEB J. 2013 23982143 Regulation of UHRF1 by miR-146a/b modulates gastric cancer invasion and metastasis.
49 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
50 Hou et al. Mol Med Rep 2012 22711166 microRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer.
51 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
52 Cowan et al. Invest. Ophthalmol. Vis. Sci. 2014 24985472 MicroRNA-146 inhibits thrombin-induced NF-κB activation and subsequent inflammatory responses in human retinal endothelial cells.
53 Cheng et al. EMBO Mol Med 2013 23733368 MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways.
54 Hung et al. PLoS ONE 2013 24302991 miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes.
55 Ghorpade et al. J. Biol. Chem. 2013 24092752 NOD2-nitric oxide-responsive microRNA-146a activates Sonic hedgehog signaling to orchestrate inflammatory responses in murine model of inflammatory bowel disease.
56 Cheung et al. PLoS ONE 2014 24892945 MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD3.
57 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
58 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
59 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
60 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
61 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
62 Liu et al. J. Gastroenterol. 2013 22699322 MicroRNA-146a negatively regulates PTGS2 expression induced by Helicobacter pylori in human gastric epithelial cells.
63 Rebane et al. J. Allergy Clin. Immunol. 2014 24996260 MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes.
64 Lu et al. PLoS ONE 2012 22815788 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.
65 Zhu et al. Exp. Mol. Pathol. 2014 25445498 A common polymorphism in pre-miR-146a underlies Hirschsprung disease risk in Han Chinese.
66 Matysiak et al. J. Immunol. 2013 23589616 MicroRNA-146a negatively regulates the immunoregulatory activity of bone marrow stem cells by targeting prostaglandin E2 synthase-2.
67 Zhou et al. J. Cell. Sci. 2013 23591815 Loss of Git2 induces epithelial-mesenchymal transition by miR146a-Cnot6L-controlled expression of Zeb1.
68 Hsieh et al. Nucleic Acids Res. 2013 23963696 miR-146a-5p circuitry uncouples cell proliferation and migration, but not differentiation, in human mesenchymal stem cells.
69 Zhang et al. Int. J. Cancer 2014 23457043 MicroRNA-146a targets PRKCE to modulate papillary thyroid tumor development.
70 Hakami et al. Br. J. Cancer 2014 25010866 The roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC).
71 Sun et al. Prostate 2014 25214035 miR-146a functions as a tumor suppressor in prostate cancer by targeting Rac1.
72 Cornett et al. RNA 2014 25047043 Regulation of COX-2 expression by miR-146a in lung cancer cells.
73 Brudecki et al. Clin. Vaccine Immunol. 2013 23825193 Mitogen-activated protein kinase phosphatase 1 disrupts proinflammatory protein synthesis in endotoxin-adapted monocytes.
74 Stewart et al. J. Virol. 2013 23345523 Promotion of Hendra virus replication by microRNA 146a.
75 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
76 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
77 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
78 Kishore et al. Genome Biol. 2013 23706177 Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing.
79 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
80 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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