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hsa-miR-141-3p (MIMAT0000432) (124 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-141-3p DLX5
Luciferase reporter assay [1]
hsa-miR-141-3p BAP1
microarray [2]
Reporter assay [3]
hsa-miR-141-3p TGFB2
qRT-PCR [4]
Immunoblot [4]
Luciferase reporter assay [4]
hsa-miR-141-3p SFPQ
Western blot [5]
Luciferase reporter assay [5]
Immunoprecipitaion [5]
hsa-miR-141-3p CLOCK
Northern blot [6]
qRT-PCR [6]
Reporter assay [7]
Western blot [6]
Luciferase reporter assay [7]
hsa-miR-141-3p BRD3
Reporter assay [8]
Western blot [8]
Other [8]
Luciferase reporter assay [8]
PAR-CLIP [9]
hsa-miR-141-3p UBAP1
Reporter assay [8]
Western blot [8]
Other [8]
Luciferase reporter assay [8]
hsa-miR-141-3p PTEN
Reporter assay [8]
Western blot [8]
Other [8]
Luciferase reporter assay [8]
PAR-CLIP [10]
hsa-miR-141-3p ZFPM2
Reporter assay [3]
Western blot [3]
Luciferase reporter assay [3]
hsa-miR-141-3p TRAPPC2B
Luciferase reporter assay [11]
hsa-miR-141-3p EIF4E
Northern blot [12]
qRT-PCR [12]
Western blot [12]
Luciferase reporter assay [12]
hsa-miR-141-3p CTBP2
Western blot [13]
Luciferase reporter assay [13]
hsa-miR-141-3p CDYL
Western blot [13]
Luciferase reporter assay [13]
hsa-miR-141-3p ACVR2B
Western blot [14]
Luciferase reporter assay [14]
hsa-miR-141-3p MAPK14
microarray [15]
Western blot [15]
HITS-CLIP [16]
Luciferase reporter assay [15]
hsa-miR-141-3p PPARA
qRT-PCR [17]
Western blot [17]
Luciferase reporter assay [17]
hsa-miR-141-3p NR0B2
Luciferase reporter assay [18]
hsa-miR-141-3p YWHAG
qRT-PCR [19]
Western blot [19]
Luciferase reporter assay [19]
hsa-miR-141-3p ELAVL4
qRT-PCR [20]
hsa-miR-141-3p MAPK9
Western blot [8]
hsa-miR-141-3p TFDP2
Western blot [8]
hsa-miR-141-3p E2F3
Western blot [8]
hsa-miR-141-3p SHC1
Reporter assay [3]
hsa-miR-141-3p VAC14
Reporter assay [3]
hsa-miR-141-3p TCF7L1
Reporter assay [3]
hsa-miR-141-3p ELMO2
Reporter assay [3]
hsa-miR-141-3p RASSF2
Reporter assay [3]
hsa-miR-141-3p KLHL20
Reporter assay [3]
hsa-miR-141-3p RIN2
Reporter assay [3]
hsa-miR-141-3p SEPT7
Reporter assay [3]
hsa-miR-141-3p HOXB5
Reporter assay [3]
hsa-miR-141-3p ERBIN
Reporter assay [3]
hsa-miR-141-3p KLF11
Reporter assay [3]
hsa-miR-141-3p PTPRD
Reporter assay [3]
hsa-miR-141-3p WDR37
Reporter assay [3]
hsa-miR-141-3p STAT4
qRT-PCR [21]
Western blot [21]
Luciferase reporter assay [21]
Immunohistochemistry [21]
hsa-miR-141-3p YAP1
Western blot [22]
Luciferase reporter assay [22]
hsa-miR-141-3p CDC25C
Western blot [23]
Luciferase reporter assay [23]
hsa-miR-141-3p HDGF
qRT-PCR [24]
Western blot [24]
Luciferase reporter assay [24]
hsa-miR-141-3p KEAP1
qRT-PCR [25] [26]
microarray [26]
Western blot [25] [26]
Luciferase reporter assay [25] [26]
hsa-miR-141-3p TAZ
qRT-PCR [27]
microarray [27]
Western blot [27]
Luciferase reporter assay [27]
hsa-miR-141-3p TIAM1
qRT-PCR [28]
Western blot [28]
Luciferase reporter assay [28]
hsa-miR-141-3p TM4SF1
qRT-PCR [29]
Western blot [29]
Luciferase reporter assay [29]
hsa-miR-141-3p CDC25A
Western blot [30]
Immunoblot [30]
Luciferase reporter assay [30]
hsa-miR-141-3p PHLPP1
qRT-PCR [31]
Luciferase reporter assay [31]
hsa-miR-141-3p PHLPP2
qRT-PCR [31]
Luciferase reporter assay [31]
hsa-miR-141-3p PPP1R15B
PAR-CLIP [10]
hsa-miR-141-3p RAB8B
PAR-CLIP [32]
hsa-miR-141-3p MED13
PAR-CLIP [9]
hsa-miR-141-3p QKI
PAR-CLIP [32]
hsa-miR-141-3p ADNP2
HITS-CLIP [33]
hsa-miR-141-3p ARL5B
PAR-CLIP [34] [32] [35] [10] [9]
hsa-miR-141-3p TNKS2
PAR-CLIP [35]
hsa-miR-141-3p SPRYD4
PAR-CLIP [35]
hsa-miR-141-3p OGT
PAR-CLIP [34] [35]
hsa-miR-141-3p PGK1
PAR-CLIP [36]
hsa-miR-141-3p ZBTB34
PAR-CLIP [10]
hsa-miR-141-3p HNRNPAB
PAR-CLIP [32]
hsa-miR-141-3p IPO5
PAR-CLIP [34]
hsa-miR-141-3p MAP4K4
qRT-PCR [37]
Western blot [37]
Luciferase reporter assay [37]
hsa-miR-141-3p HNRNPD
Western blot [38]
Luciferase reporter assay [38]
hsa-miR-141-3p ZMPSTE24
Luciferase reporter assay [39]
hsa-miR-141-3p STXBP2
PAR-CLIP [40]
hsa-miR-141-3p SEPT8
PAR-CLIP [40]
hsa-miR-141-3p DPY19L1
PAR-CLIP [40]
hsa-miR-141-3p CHML
PAR-CLIP [40]
hsa-miR-141-3p NDST4
PAR-CLIP [40]
hsa-miR-141-3p TRAM1
PAR-CLIP [10]
hsa-miR-141-3p YRDC
HITS-CLIP [35]
PAR-CLIP [10] [9] [34] [32] [35] [36]
hsa-miR-141-3p PSMD11
PAR-CLIP [10]
hsa-miR-141-3p MCL1
PAR-CLIP [10]
hsa-miR-141-3p CYP1B1
PAR-CLIP [10]
hsa-miR-141-3p BICD2
PAR-CLIP [35] [10]
hsa-miR-141-3p PRELID2
PAR-CLIP [41]
hsa-miR-141-3p USP53
PAR-CLIP [9]
hsa-miR-141-3p HNRNPF
PAR-CLIP [35] [9]
hsa-miR-141-3p GNA13
PAR-CLIP [9]
hsa-miR-141-3p FUT11
PAR-CLIP [35] [9]
hsa-miR-141-3p EPHA2
PAR-CLIP [36] [9]
hsa-miR-141-3p TMOD3
PAR-CLIP [34] [32]
hsa-miR-141-3p MARCH6
PAR-CLIP [35] [36] [34] [32]
hsa-miR-141-3p KIAA1147
PAR-CLIP [34]
hsa-miR-141-3p ZNF805
PAR-CLIP [34] [35]
hsa-miR-141-3p ZMAT3
PAR-CLIP [34] [35]
hsa-miR-141-3p MALT1
PAR-CLIP [36]
hsa-miR-141-3p KIAA1549
PAR-CLIP [36]
hsa-miR-141-3p ELAVL2
PAR-CLIP [36]
hsa-miR-141-3p ATXN7L1
PAR-CLIP [36]
hsa-miR-141-3p PIGW
PAR-CLIP [35]
hsa-miR-141-3p GATA6
PAR-CLIP [35]
hsa-miR-141-3p EPHA7
PAR-CLIP [35]
hsa-miR-141-3p C18orf25
PAR-CLIP [35]
hsa-miR-141-3p SLC35D1
PAR-CLIP [35]
hsa-miR-141-3p PGAM4
PAR-CLIP [35]
hsa-miR-141-3p H2AFZ
PAR-CLIP [32] [35]
hsa-miR-141-3p TRMT112
PAR-CLIP [32]
hsa-miR-141-3p XPOT
PAR-CLIP [32]
hsa-miR-141-3p CDV3
PAR-CLIP [32]
hsa-miR-141-3p KIAA1549L
PAR-CLIP [32]
hsa-miR-141-3p LHX1
HITS-CLIP [16]
hsa-miR-141-3p YME1L1
HITS-CLIP [16]
hsa-miR-141-3p APOOL
HITS-CLIP [16]
hsa-miR-141-3p ZNF621
HITS-CLIP [16]
hsa-miR-141-3p ANGPTL7
HITS-CLIP [16]
hsa-miR-141-3p PRKAA2
HITS-CLIP [16]
hsa-miR-141-3p MACC1
HITS-CLIP [16]
hsa-miR-141-3p CCDC18
HITS-CLIP [16]
hsa-miR-141-3p DNAJC28
HITS-CLIP [42]
hsa-miR-141-3p ZNF292
HITS-CLIP [42]
hsa-miR-141-3p RPL12
HITS-CLIP [42]
hsa-miR-141-3p A1BG
HITS-CLIP [42]
hsa-miR-141-3p POLR3F
HITS-CLIP [33]
hsa-miR-141-3p COX6B1
HITS-CLIP [33]
hsa-miR-141-3p RBM28
HITS-CLIP [33]
hsa-miR-141-3p LPP
HITS-CLIP [33]
hsa-miR-141-3p CCDC71L
HITS-CLIP [43]
hsa-miR-141-3p TROVE2
HITS-CLIP [43]
hsa-miR-141-3p BICRAL
HITS-CLIP [43]
hsa-miR-141-3p ERO1A
HITS-CLIP [43]
hsa-miR-141-3p HSPA4
HITS-CLIP [43]
hsa-miR-141-3p SCD5
HITS-CLIP [43]
hsa-miR-141-3p CLDND1
HITS-CLIP [43]
hsa-miR-141-3p PEX11A
HITS-CLIP [43]
hsa-miR-141-3p CELF1
HITS-CLIP [43]

References

authors journal year Pubmed link title
1 Itoh et al. J. Biol. Chem. 2009 19454767 MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5.
2 Iorio et al. Cancer Res. 2007 17875710 MicroRNA signatures in human ovarian cancer.
3 Hyun et al. Cell 2009 20005803 Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K.
4 Burk et al. EMBO Rep. 2008 18483486 A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells.
5 Beitzinger et al. RNA Biol 2007 17637574 Identification of human microRNA targets from isolated argonaute protein complexes.
6 Meng et al. Gastroenterology 2006 16762633 Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines.
7 Kiriakidou et al. Genes Dev. 2004 15131085 A combined computational-experimental approach predicts human microRNA targets.
8 Zhang et al. Carcinogenesis 2010 20053927 microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network.
9 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
10 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
11 Wu et al. Gastroenterology 2008 18835392 MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha.
12 Ho et al. Cell Host Microbe 2011 21238947 Enterovirus-induced miR-141 contributes to shutoff of host protein translation by targeting the translation initiation factor eIF4E.
13 Sass et al. BMC Syst Biol 2011 21867514 MicroRNAs coordinately regulate protein complexes.
14 Senanayake et al. Carcinogenesis 2012 22431721 miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.
15 Mateescu et al. Nat. Med. 2011 22101765 miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response.
16 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
17 Hu et al. PLoS ONE 2012 22479552 MicroRNA-141 represses HBV replication by targeting PPARA.
18 Xiao et al. Prostate 2012 22314666 miR-141 modulates androgen receptor transcriptional activity in human prostate cancer cells through targeting the small heterodimer partner protein.
19 Capobianco et al. J. Proteome Res. 2012 22537031 miRNA and protein expression profiles of visceral adipose tissue reveal miR-141/YWHAG and miR-520e/RAB11A as two potential miRNA/protein target pairs associated with severe obesity.
20 Abdelmohsen et al. Mol. Cell. Biol. 2010 20584986 miR-375 inhibits differentiation of neurites by lowering HuD levels.
21 Zhou et al. Cell. Physiol. Biochem. 2014 24732377 Down-regulation of miR-141 induced by helicobacter pylori promotes the invasion of gastric cancer by targeting STAT4.
22 Zhu et al. Mol. Cell. Biochem. 2014 24242138 Prognostic significance of microRNA-141 expression and its tumor suppressor function in human pancreatic ductal adenocarcinoma.
23 Yu et al. Onco Targets Ther 2013 23596351 MicroRNA-141 is downregulated in human renal cell carcinoma and regulates cell survival by targeting CDC25B.
24 Chen et al. Mol. Cell. Biochem. 2014 24276755 miR-141 suppresses proliferation and motility of gastric cancer cells by targeting HDGF.
25 Zhou et al. Helicobacter 2014 24628843 Helicobacter pylori modulates cisplatin sensitivity in gastric cancer by down-regulating miR-141 expression.
26 van Jaarsveld et al. Oncogene 2013 23045278 miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells.
27 Zuo et al. Cell Death Dis 2015 25633292 MicroRNA-141 inhibits tumor growth and metastasis in gastric cancer by directly targeting transcriptional co-activator with PDZ-binding motif, TAZ.
28 Liu et al. PLoS ONE 2014 24551096 MiR-141 suppresses the migration and invasion of HCC cells by targeting Tiam1.
29 Xu et al. Int. J. Oncol. 2014 24285464 hsa-miR-141 downregulates TM4SF1 to inhibit pancreatic cancer cell invasion and migration.
30 Qiu et al. Biochim. Biophys. Acta 2014 24937190 miR-141-3p inhibits human stromal (mesenchymal) stem cell proliferation and differentiation.
31 Mei et al. FEBS Lett. 2014 24945731 MicroRNA-141 promotes the proliferation of non-small cell lung cancer cells by regulating expression of PHLPP1 and PHLPP2.
32 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
33 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
34 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
35 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
36 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
37 Zhao et al. Mol. Cancer Ther. 2013 24013097 miRNA-141, downregulated in pancreatic cancer, inhibits cell proliferation and invasion by directly targeting MAP4K4.
38 Al-Khalaf et al. J. Biol. Chem. 2014 25261470 MicroRNA-141 and microRNA-146b-5p inhibit the prometastatic mesenchymal characteristics through the RNA-binding protein AUF1 targeting the transcription factor ZEB1 and the protein kinase AKT.
39 Yu et al. J. Cell. Sci. 2013 24101728 MicroRNA-141-3p plays a role in human mesenchymal stem cell aging by directly targeting ZMPSTE24.
40 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
41 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
42 Kishore et al. Genome Biol. 2013 23706177 Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing.
43 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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