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hsa-miR-140-5p (MIMAT0000431) (85 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-140-5p Egr2
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
Immunohistochemistry [1]
hsa-miR-140-5p HDAC4
qRT-PCR [2]
Western blot [2]
Luciferase reporter assay [2]
hsa-miR-140-5p VEGFA
Luciferase reporter assay [3]
ELISA [3]
hsa-miR-140-5p CSK
microarray [4]
hsa-miR-140-5p MMP13
qRT-PCR [5]
microarray [4]
hsa-miR-140-5p FGF2
microarray [4]
hsa-miR-140-5p PDGFRA
Western blot [6]
Luciferase reporter assay [6]
hsa-miR-140-5p IGFBP5
qRT-PCR [5]
hsa-miR-140-5p DNMT1
qRT-PCR [7]
microarray [7]
Western blot [7]
Luciferase reporter assay [7]
Immunohistochemistry [7]
hsa-miR-140-5p DNPEP
Luciferase reporter assay [8]
hsa-miR-140-5p SOX2
Luciferase reporter assay [9]
hsa-miR-140-5p OSTM1
Luciferase reporter assay [10]
hsa-miR-140-5p FGF9
Luciferase reporter assay [11]
hsa-miR-140-5p TGFBR1
Luciferase reporter assay [11]
hsa-miR-140-5p CYTB
CLASH [12]
hsa-miR-140-5p EP300
CLASH [12]
hsa-miR-140-5p CASD1
CLASH [12]
hsa-miR-140-5p PRPF8
CLASH [12]
hsa-miR-140-5p GATA6
CLASH [12]
hsa-miR-140-5p ALDH1A1
Western blot [13]
Luciferase reporter assay [13]
hsa-miR-140-5p SOX9
Western blot [13]
Luciferase reporter assay [13]
hsa-miR-140-5p IGF1R
qRT-PCR [14]
Western blot [14]
Luciferase reporter assay [14]
Flow cytometry [14]
hsa-miR-140-5p ARIH1
PAR-CLIP [15] [16]
hsa-miR-140-5p SMCR8
PAR-CLIP [17] [16] [18]
hsa-miR-140-5p SEPT2
PAR-CLIP [17] [15] [16]
hsa-miR-140-5p RAB10
PAR-CLIP [15] [16]
hsa-miR-140-5p FZD6
PAR-CLIP [15] [16] [18]
hsa-miR-140-5p SPRED1
PAR-CLIP [17]
hsa-miR-140-5p LDLR
HITS-CLIP [19]
hsa-miR-140-5p FXR1
PAR-CLIP [20]
hsa-miR-140-5p FEN1
PAR-CLIP [15]
hsa-miR-140-5p CAPN1
PAR-CLIP [21]
hsa-miR-140-5p GLRX5
PAR-CLIP [16]
hsa-miR-140-5p SPCS3
PAR-CLIP [16]
hsa-miR-140-5p PHACTR2
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p STRADB
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p SNX16
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p RALA
qRT-PCR [22]
microarray [22]
Luciferase reporter assay [23]
hsa-miR-140-5p RIOK3
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p KATNBL1
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p PRDM1
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p MYO6
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p CAMK2N1
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p MRPS10
qRT-PCR [22]
microarray [22]
hsa-miR-140-5p PAX6
Western blot [24]
Luciferase reporter assay [24]
hsa-miR-140-5p HDAC7
Western blot [24]
Luciferase reporter assay [24]
hsa-miR-140-5p LAMC1
Western blot [24]
Luciferase reporter assay [24]
hsa-miR-140-5p ADA
Western blot [24]
Luciferase reporter assay [24]
hsa-miR-140-5p MMD
Luciferase reporter assay [25]
hsa-miR-140-5p GPR107
PAR-CLIP [26]
hsa-miR-140-5p CEBPD
PAR-CLIP [20]
hsa-miR-140-5p RPUSD2
PAR-CLIP [20]
hsa-miR-140-5p ZNF426
PAR-CLIP [20]
hsa-miR-140-5p NDUFA2
PAR-CLIP [20]
hsa-miR-140-5p TSC22D2
PAR-CLIP [20] [18]
hsa-miR-140-5p RAB30
PAR-CLIP [20]
hsa-miR-140-5p KLK10
PAR-CLIP [20]
hsa-miR-140-5p EFHD2
PAR-CLIP [20]
hsa-miR-140-5p BCL2L11
PAR-CLIP [20]
hsa-miR-140-5p AIDA
PAR-CLIP [20]
hsa-miR-140-5p LYRM2
PAR-CLIP [16] [18]
hsa-miR-140-5p ZC3H11A
PAR-CLIP [18]
hsa-miR-140-5p ZNF652
PAR-CLIP [17]
hsa-miR-140-5p TMED4
PAR-CLIP [17]
hsa-miR-140-5p YIPF4
HITS-CLIP [27]
PAR-CLIP [21]
hsa-miR-140-5p RNF149
PAR-CLIP [21]
hsa-miR-140-5p PLEKHA8
PAR-CLIP [21]
hsa-miR-140-5p MED13
PAR-CLIP [21]
hsa-miR-140-5p CNKSR2
PAR-CLIP [21]
hsa-miR-140-5p VEZF1
PAR-CLIP [16]
hsa-miR-140-5p TSPAN12
PAR-CLIP [16]
hsa-miR-140-5p LIN28B
PAR-CLIP [16]
hsa-miR-140-5p ZCCHC2
PAR-CLIP [16]
hsa-miR-140-5p YOD1
PAR-CLIP [16]
hsa-miR-140-5p TM7SF3
PAR-CLIP [16]
hsa-miR-140-5p BRAP
PAR-CLIP [16]
hsa-miR-140-5p PANK3
PAR-CLIP [15]
hsa-miR-140-5p RPRD2
PAR-CLIP [15]
hsa-miR-140-5p PPIE
HITS-CLIP [27]
hsa-miR-140-5p ESR2
HITS-CLIP [19]
hsa-miR-140-5p DST
HITS-CLIP [19]
hsa-miR-140-5p ACTR5
HITS-CLIP [16]
hsa-miR-140-5p CUBN
HITS-CLIP [28]
hsa-miR-140-5p STK24
HITS-CLIP [28]
hsa-miR-140-5p ZDHHC21
HITS-CLIP [28]

References

authors journal year Pubmed link title
1 Viader et al. J. Neurosci. 2011 22131398 MicroRNAs modulate Schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related genes.
2 Song et al. Oncogene 2009 19734943 Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells.
3 Ye et al. PLoS ONE 2008 18320040 The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.
4 Iorio et al. Cancer Res. 2007 17875710 MicroRNA signatures in human ovarian cancer.
5 Tardif et al. BMC Musculoskelet Disord 2009 19948051 Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.
6 Li et al. Am. J. Med. Genet. A 2011 22012839 Biological and epidemiological evidence of interaction of infant genotypes at Rs7205289 and maternal passive smoking in cleft palate.
7 Takata et al. Hepatology 2013 22898998 MicroRNA-140 acts as a liver tumor suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression.
8 Nakamura et al. Mol. Cell. Biol. 2011 21576357 Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling.
9 Zhang et al. J. Biol. Chem. 2012 23060440 Estrogen receptor α signaling regulates breast tumor-initiating cells by down-regulating miR-140 which targets the transcription factor SOX2.
10 Liu et al. J. Biol. Chem. 2013 23389033 MicroRNA-140 promotes adipocyte lineage commitment of C3H10T1/2 pluripotent stem cells via targeting osteopetrosis-associated transmembrane protein 1.
11 Yang et al. Hepatology 2013 23401231 MicroRNA-140-5p suppresses tumor growth and metastasis by targeting transforming growth factor β receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma.
12 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
13 Li et al. Oncogene 2014 23752191 Downregulation of miR-140 promotes cancer stem cell formation in basal-like early stage breast cancer.
14 Yuan et al. PLoS ONE 2013 24039995 miR-140 suppresses tumor growth and metastasis of non-small cell lung cancer by targeting insulin-like growth factor 1 receptor.
15 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
16 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
17 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
18 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
19 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
20 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
21 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
22 Lu et al. PLoS ONE 2012 22815788 MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.
23 Karlsen et al. Stem Cells Dev. 2014 24063364 microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN.
24 Kai et al. Biochem. Biophys. Res. Commun. 2014 24530397 Reciprocal effects between microRNA-140-5p and ADAM10 suppress migration and invasion of human tongue cancer cells.
25 Li et al. Biochem. Biophys. Res. Commun. 2014 24971538 Monocyte to macrophage differentiation-associated (MMD) targeted by miR-140-5p regulates tumor growth in non-small cell lung cancer.
26 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
27 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
28 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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