Targets miRBase

hsa-miR-124-3p (MIMAT0000422) (1348 targets) in miRTarBase

References

authors journal year Pubmed link title
1 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
2 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
3 Bahi et al. Eur. J. Neurosci. 2013 23601049 Striatal modulation of BDNF expression using microRNA124a-expressing lentiviral vectors impairs ethanol-induced conditioned-place preference and voluntary alcohol consumption.
4 Arvanitis et al. Mol. Cell. Biol. 2010 20308325 Ephrin-B1 reverse signaling controls a posttranscriptional feedback mechanism via miR-124.
5 Sõber et al. Biochem. Biophys. Res. Commun. 2010 19944075 MicroRNAs miR-124 and miR-135a are potential regulators of the mineralocorticoid receptor gene (NR3C2) expression.
6 Wang et al. Nucleic Acids Res. 2006 16549876 Systematic identification of microRNA functions by combining target prediction and expression profiling.
7 Krek et al. Nat. Genet. 2005 15806104 Combinatorial microRNA target predictions.
8 Lim et al. Nature 2005 15685193 Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.
9 Hackanson et al. Cancer Res. 2008 18451139 Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia.
10 Baek et al. Nature 2008 18668037 The impact of microRNAs on protein output.
11 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
12 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
13 Lv et al. Chin J Cancer 2011 22085528 miR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro.
14 Lawson et al. Mol. Cell. Biol. 2013 23109423 p38α mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neurons.
15 Furuta et al. Carcinogenesis 2010 19843643 miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma.
16 Lujambio et al. Cancer Res. 2007 17308079 Genetic unmasking of an epigenetically silenced microRNA in human cancer cells.
17 Agirre et al. Cancer Res. 2009 19435910 Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia.
18 Pierson et al. J. Neurooncol. 2008 18607543 Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma.
19 Chen et al. Invest. Ophthalmol. Vis. Sci. 2013 23404119 MicroRNA-124a is epigenetically regulated and acts as a tumor suppressor by controlling multiple targets in uveal melanoma.
20 Lujambio et al. Cell Cycle 2007 17581274 CpG island hypermethylation of tumor suppressor microRNAs in human cancer.
21 Silber et al. BMC Med 2008 18577219 miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.
22 Sun et al. Oncol. Rep. 2012 22895557 miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect.
23 Kang et al. J. Biol. Chem. 2013 23853098 MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells.
24 Wang et al. Circ. Res. 2014 24122720 MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts.
25 Ferrarese et al. J. Clin. Invest. 2014 24865424 Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.
26 Huang et al. FEBS Lett. 2011 22024478 Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR.
27 Li et al. Hum. Pathol. 2009 19427019 miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1.
28 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
29 Fowler et al. Eur. J. Cancer 2011 21196113 miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion.
30 Liang et al. Carcinogenesis 2013 23250910 MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer.
31 Fornari et al. J. Pathol. 2012 22262409 In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.
32 Xia et al. J. Biol. Chem. 2012 22253443 Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells.
33 Yang et al. Mol. Cell. Biochem. 2013 24000013 MicroRNA-124 reduces caveolar density by targeting caveolin-1 in porcine kidney epithelial PK15 cells.
34 Visvanathan et al. Genes Dev. 2007 17403776 The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development.
35 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
36 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
37 Hunt et al. FEBS Lett. 2011 21112327 MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1.
38 Arora et al. Invest. Ophthalmol. Vis. Sci. 2007 17724173 Prediction and verification of miRNA expression in human and rat retinas.
39 Takane et al. BMC Genomics 2010 20144220 Computational prediction and experimental validation of evolutionarily conserved microRNA target genes in bilaterian animals.
40 Liu et al. Biomed Res Int 2013 23691514 MicroRNA-124 regulates the proliferation of colorectal cancer cells by targeting iASPP.
41 Zhao et al. Int. J. Mol. Med. 2013 23624869 Downregulation of miR-124 promotes the growth and invasiveness of glioblastoma cells involving upregulation of PPP1R13L.
42 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
43 Nakamachi et al. Arthritis Rheum. 2009 19404929 MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis.
44 Vreugdenhil et al. Endocrinology 2009 19131573 MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain.
45 Zeng et al. FEBS Lett. 2012 22819820 Epigenetic regulation of miR-124 by hepatitis C virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3.
46 Lindenblatt et al. Cell Cycle 2009 19502795 IkappaBzeta expression is regulated by miR-124a.
47 Stanley et al. J. Steroid Biochem. Mol. Biol. 2012 22386953 Androgen receptor expression in human thyroid cancer tissues: a potential mechanism underlying the gender bias in the incidence of thyroid cancers.
48 Shi et al. Oncogene 2013 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells.
49 Zheng et al. Gut 2012 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2.
50 Neo et al. J. Biol. Chem. 2014 24878960 MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression.
51 Xie et al. Mol. Cell. Biochem. 2014 24658854 MicroRNA-124 inhibits proliferation and induces apoptosis by directly repressing EZH2 in gastric cancer.
52 Hatziapostolou et al. Cell 2011 22153071 An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis.
53 Lau et al. Acta Neuropathol. 2012 22249617 Overexpression of HMGA1 deregulates tumor growth via cdc25A and alters migration/invasion through a cdc25A-independent pathway in medulloblastoma.
54 An et al. PLoS ONE 2013 23936026 microRNA-124 inhibits migration and invasion by down-regulating ROCK1 in glioma.
55 Hu et al. Asian Pac. J. Cancer Prev. 2014 25169484 miR-124 inhibits growth and invasion of gastric cancer by targeting ROCK1.
56 Lang et al. Biochem. Biophys. Res. Commun. 2012 22940133 MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA.
57 Bandiera et al. PLoS ONE 2013 23382970 Genetic variations creating microRNA target sites in the FXN 3'-UTR affect frataxin expression in Friedreich ataxia.
58 Kynast et al. Pain 2013 23318130 Modulation of central nervous system-specific microRNA-124a alters the inflammatory response in the formalin test in mice.
59 Shi et al. Neuro-oncology 2014 24861879 MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras.
60 Zhang et al. PLoS ONE 2014 24705396 MiR-124 Radiosensitizes human colorectal cancer cells by targeting PRRX1.
61 Nagata et al. Neuroscience 2014 24184980 microRNA-124 is down regulated in nerve-injured motor neurons and it potentially targets mRNAs for KLF6 and STAT3.
62 Han et al. Cell. Physiol. Biochem. 2013 23816858 MicroRNA-124 suppresses breast cancer cell growth and motility by targeting CD151.
63 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
64 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
65 Koukos et al. Gastroenterology 2013 23856509 MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis.
66 Li et al. Mol. Cell. Biochem. 2014 24287565 miR-124 functions as a tumor suppressor in the endometrial carcinoma cell line HEC-1B partly by suppressing STAT3.
67 Zhang et al. PLoS ONE 2013 23940556 MiR-124 suppresses growth of human colorectal cancer by inhibiting STAT3.
68 Lu et al. Biochem. Biophys. Res. Commun. 2013 24211205 MicroRNA-124 suppresses growth of human hepatocellular carcinoma by targeting STAT3.
69 Wang et al. Oncogene 2014 23334332 Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1.
70 Ahluwalia et al. RNA Biol 2012 22336710 Modeling SNP mediated differential targeting of homologous 3'UTR by microRNA.
71 Li et al. FEBS Lett. 2013 23792158 Circadian gene Clock contributes to cell proliferation and migration of glioma and is directly regulated by tumor-suppressive miR-124.
72 Lee et al. Oncotarget 2013 23548312 Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal.
73 Tivnan et al. Tumour Biol. 2014 24068568 The tumor suppressor microRNA, miR-124a, is regulated by epigenetic silencing and by the transcriptional factor, REST in glioblastoma.
74 Gong et al. Eur Neuropsychopharmacol 2013 23332465 Polymorphisms in microRNA target sites influence susceptibility to schizophrenia by altering the binding of miRNAs to their targets.
75 Wan et al. Cancer Lett. 2014 25218344 MiR-124 represses vasculogenic mimicry and cell motility by targeting amotL1 in cervical cancer cells.
76 Dutta et al. Ann. Neurol. 2013 23595422 Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors.
77 Lv et al. Mol Med Rep 2013 23817964 MiR-124 inhibits the growth of glioblastoma through the downregulation of SOS1.
78 Zhang et al. PLoS ONE 2013 23451109 Genetic variation of ITGB3 is associated with asthma in Chinese Han children.
79 Zhu et al. J. Mol. Neurosci. 2014 24166354 MicroRNA-124 (miR-124) regulates Ku70 expression and is correlated with neuronal death induced by ischemia/reperfusion.
80 Li et al. Mol. Cancer 2013 24330780 Microrna-124 targets flotillin-1 to regulate proliferation and migration in breast cancer.
81 Liu et al. Mol. Cancer 2014 24775712 Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer.
82 Nygren et al. Br. J. Cancer 2014 24577056 Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c.
83 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
84 Kishore et al. Genome Biol. 2013 23706177 Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing.
85 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
This website uses Matomo Analytics and cookies. For more information, please refer to the privacy notice for our websites. Learn moreI agree