Targets miRBase

rno-miR-1-3p (MIMAT0003125) (17 targets) in miRTarBase

miRNA gene name experiments
rno-miR-1-3p Kcnj2
qRT-PCR [1] [2]
Western blot [1] [2]
Luciferase reporter assay [1]
rno-miR-1-3p Gja1
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
rno-miR-1-3p Hcn4
qRT-PCR [3]
Reporter assay [3]
Western blot [3]
rno-miR-1-3p Hcn2
qRT-PCR [3] [4]
Reporter assay [3]
Western blot [3] [4]
rno-miR-1-3p Igf1
qRT-PCR [5]
Luciferase reporter assay [5]
ELISA [6]
rno-miR-1-3p Hspa4
qRT-PCR [7]
Western blot [7]
rno-miR-1-3p Hspd1
qRT-PCR [7]
Western blot [7]
rno-miR-1-3p Bcl2
qRT-PCR [8]
Reporter assay [8]
Western blot [8]
Other [8]
Luciferase reporter assay [8]
rno-miR-1-3p Pax3
Luciferase reporter assay [9]
rno-miR-1-3p Anxa5
Luciferase reporter assay [10]
rno-miR-1-3p Slc8a1
Luciferase reporter assay [10]
rno-miR-1-3p Calm3
qRT-PCR [11]
rno-miR-1-3p Gata4
qRT-PCR [11]
Western blot [11]
rno-miR-1-3p Calm2
qRT-PCR [11]
Reporter assay [11]
Western blot [11]
rno-miR-1-3p Mef2a
qRT-PCR [11]
Reporter assay [11]
Western blot [11]
rno-miR-1-3p Calm1
qRT-PCR [11]
Reporter assay [11]
Western blot [11]
rno-miR-1-3p ASPH
Luciferase reporter assay [12]

References

authors journal year Pubmed link title
1 Yang et al. Nat. Med. 2007 17401374 The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2.
2 Shan et al. Br. J. Pharmacol. 2009 19775284 Tanshinone IIA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1.
3 Xiao et al. J. Cell. Physiol. 2007 17516552 Novel approaches for gene-specific interference via manipulating actions of microRNAs: examination on the pacemaker channel genes HCN2 and HCN4.
4 Luo et al. J. Biol. Chem. 2008 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart.
5 Shan et al. Biochem. Biophys. Res. Commun. 2009 19245789 Upregulated expression of miR-1/miR-206 in a rat model of myocardial infarction.
6 Yu et al. Biochem. Biophys. Res. Commun. 2008 18801338 Glucose induces apoptosis of cardiomyocytes via microRNA-1 and IGF-1.
7 Xu et al. J. Cell. Sci. 2007 17715156 The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes.
8 Tang et al. Int Heart J 2009 19506341 MicroRNA-1 regulates cardiomyocyte apoptosis by targeting Bcl-2.
9 Goljanek-Whysall et al. Proc. Natl. Acad. Sci. U.S.A. 2011 21730146 MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesis.
10 Tritsch et al. Cardiovasc. Res. 2013 23436819 An SRF/miR-1 axis regulates NCX1 and annexin A5 protein levels in the normal and failing heart.
11 Ikeda et al. Mol. Cell. Biol. 2009 19188439 MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes.
12 Yildirim et al. Cell Biochem. Biophys. 2013 23723006 Relationship between downregulation of miRNAs and increase of oxidative stress in the development of diabetic cardiac dysfunction: junctin as a target protein of miR-1.