miRCarta - targets

hsa-miR-486-5p (MIMAT0002177) (51 targets) in miRTarBase

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hsa-miR-486-5p


qRT-PCR	[1]
microarray	[1]

hsa-miR-486-5p


CLASH	[2]

hsa-miR-486-5p


qRT-PCR	[3]
Western blot	[3]
Luciferase reporter assay	[3]
Immunohistochemistry	[3]

hsa-miR-486-5p


qRT-PCR	[4]
microarray	[4]
In situ hybridization	[4]
Western blot	[4]
Luciferase reporter assay	[4]

hsa-miR-486-5p


qRT-PCR	[5]

hsa-miR-486-5p


PAR-CLIP	[6] [7] [8]

hsa-miR-486-5p


qRT-PCR	[9]

hsa-miR-486-5p


PAR-CLIP	[6]

hsa-miR-486-5p


qRT-PCR	[10]
Western blot	[10]
Luciferase reporter assay	[10]

hsa-miR-486-5p


qRT-PCR	[11]
Immunofluorescence	[11]
Western blot	[11]
Luciferase reporter assay	[11]
Immunoprecipitaion	[11]
Immunohistochemistry	[11]

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References

	authors	journal	year	Pubmed link	title
1	Mees et al.	Ann. Surg. Oncol.	2009	19475450	Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas.
2	Helwak et al.	Cell	2013	23622248	Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
3	Wang et al.	Oncogene	2014	23474761	Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer.
4	Oh et al.	Clin. Cancer Res.	2011	21415212	Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer.
5	Borjigin et al.	Biochem. Biophys. Res. Commun.	2012	22995304	TLS-CHOP represses miR-486 expression, inducing upregulation of a metastasis regulator PAI-1 in human myxoid liposarcoma.
6	Memczak et al.	Nature	2013	23446348	Circular RNAs are a large class of animal RNAs with regulatory potency.
7	Hafner et al.	Cell	2010	20371350	Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
8	Lipchina et al.	Genes Dev.	2011	22012620	Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
9	Li et al.	Int. J. Pediatr. Otorhinolaryngol.	2013	23294929	MicroRNA expression profiling and target genes study in congenital microtia.
10	Peng et al.	Proc. Natl. Acad. Sci. U.S.A.	2013	23980150	Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.
11	Alexander et al.	J. Clin. Invest.	2014	24789910	MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.
12	Whisnant et al.	MBio	2013	23592263	In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
13	Kishore et al.	Nat. Methods	2011	21572407	A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
14	Gottwein et al.	Cell Host Microbe	2011	22100165	Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
15	Skalsky et al.	PLoS Pathog.	2012	22291592	The viral and cellular microRNA targetome in lymphoblastoid cell lines.
16	Karginov et al.	Genes Dev.	2013	23824327	Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
17	Pillai et al.	Breast Cancer Res. Treat.	2014	24906430	HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.
18	Xue et al.	Cell	2013	23313552	Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
19	Chi et al.	Nature	2009	19536157	Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.

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