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hsa-miR-486-5p (MIMAT0002177) (51 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-486-5p CD40
qRT-PCR [1]
microarray [1]
hsa-miR-486-5p TMED1
CLASH [2]
hsa-miR-486-5p ARHGAP5
qRT-PCR [3]
Western blot [3]
Luciferase reporter assay [3]
Immunohistochemistry [3]
hsa-miR-486-5p OLFM4
qRT-PCR [4]
microarray [4]
In situ hybridization [4]
Western blot [4]
Luciferase reporter assay [4]
hsa-miR-486-5p SERPINE1
qRT-PCR [5]
hsa-miR-486-5p ID4
PAR-CLIP [6] [7] [8]
hsa-miR-486-5p PIM1
qRT-PCR [9]
hsa-miR-486-5p ZNRF2
PAR-CLIP [6]
hsa-miR-486-5p IGF1R
qRT-PCR [10]
Western blot [10]
Luciferase reporter assay [10]
hsa-miR-486-5p DOCK3
qRT-PCR [11]
Immunofluorescence [11]
Western blot [11]
Luciferase reporter assay [11]
Immunoprecipitaion [11]
Immunohistochemistry [11]
hsa-miR-486-5p CADM1
qRT-PCR [9]
PAR-CLIP [7]
hsa-miR-486-5p H3F3B
qRT-PCR [9]
PAR-CLIP [6] [7] [12] [13]
hsa-miR-486-5p PCCA
PAR-CLIP [14]
hsa-miR-486-5p ZDHHC20
PAR-CLIP [13]
hsa-miR-486-5p UBASH3B
PAR-CLIP [13]
hsa-miR-486-5p RCOR3
PAR-CLIP [15]
hsa-miR-486-5p ZNF460
PAR-CLIP [7] [6]
hsa-miR-486-5p ZIC5
PAR-CLIP [6] [7] [12]
hsa-miR-486-5p BTF3L4
PAR-CLIP [6] [7] [12]
hsa-miR-486-5p CCDC14
PAR-CLIP [8]
hsa-miR-486-5p CMSS1
PAR-CLIP [8]
hsa-miR-486-5p TTC8
PAR-CLIP [12]
hsa-miR-486-5p RBM12B
PAR-CLIP [12]
hsa-miR-486-5p MBD4
PAR-CLIP [12]
hsa-miR-486-5p FAM217B
PAR-CLIP [12]
hsa-miR-486-5p IGSF3
PAR-CLIP [7]
hsa-miR-486-5p YAE1D1
HITS-CLIP [12] [16] [17]
hsa-miR-486-5p SEL1L3
HITS-CLIP [18] [16]
hsa-miR-486-5p FOXP1
HITS-CLIP [16]
hsa-miR-486-5p TM4SF20
HITS-CLIP [16]
hsa-miR-486-5p MARCH4
HITS-CLIP [16]
hsa-miR-486-5p SP4
HITS-CLIP [16]
hsa-miR-486-5p SEC23IP
HITS-CLIP [16]
hsa-miR-486-5p BAG2
HITS-CLIP [16]
hsa-miR-486-5p METTL27
HITS-CLIP [16]
hsa-miR-486-5p DENND5B
HITS-CLIP [16]
hsa-miR-486-5p MACROD2
HITS-CLIP [16]
hsa-miR-486-5p UTP4
HITS-CLIP [16]
hsa-miR-486-5p LTBP2
HITS-CLIP [16]
hsa-miR-486-5p ARF6
HITS-CLIP [16]
hsa-miR-486-5p RBM22
HITS-CLIP [16]
hsa-miR-486-5p SAPCD2
HITS-CLIP [19]
hsa-miR-486-5p BASP1
HITS-CLIP [19]
hsa-miR-486-5p CENPN
HITS-CLIP [19]
hsa-miR-486-5p CRIPT
HITS-CLIP [19]
hsa-miR-486-5p DCTN4
HITS-CLIP [19]
hsa-miR-486-5p SPRTN
HITS-CLIP [19]
hsa-miR-486-5p EPGN
HITS-CLIP [19]
hsa-miR-486-5p HPGD
HITS-CLIP [19]
hsa-miR-486-5p FAM46A
HITS-CLIP [19]
hsa-miR-486-5p ABCF2
HITS-CLIP [19]

References

authors journal year Pubmed link title
1 Mees et al. Ann. Surg. Oncol. 2009 19475450 Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas.
2 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
3 Wang et al. Oncogene 2014 23474761 Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer.
4 Oh et al. Clin. Cancer Res. 2011 21415212 Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer.
5 Borjigin et al. Biochem. Biophys. Res. Commun. 2012 22995304 TLS-CHOP represses miR-486 expression, inducing upregulation of a metastasis regulator PAI-1 in human myxoid liposarcoma.
6 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
7 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
8 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
9 Li et al. Int. J. Pediatr. Otorhinolaryngol. 2013 23294929 MicroRNA expression profiling and target genes study in congenital microtia.
10 Peng et al. Proc. Natl. Acad. Sci. U.S.A. 2013 23980150 Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.
11 Alexander et al. J. Clin. Invest. 2014 24789910 MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.
12 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
13 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
14 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
15 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
16 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
17 Pillai et al. Breast Cancer Res. Treat. 2014 24906430 HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.
18 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
19 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
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