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hsa-miR-224-5p (MIMAT0000281) (112 targets) in miRTarBase

References

authors journal year Pubmed link title
1 White et al. Br. J. Cancer 2010 20354523 Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer.
2 Zhu et al. Oncogene 2010 20023705 Ubc9 promotes breast cell invasion and metastasis in a sumoylation-independent manner.
3 Ke et al. Dis. Markers 2014 24817781 MicroRNA-224 suppresses colorectal cancer cell migration by targeting Cdc42.
4 Zhang et al. J. Gastroenterol. Hepatol. 2013 22989374 Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma.
5 Murakami et al. Oncogene 2006 16331254 Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues.
6 Mouillet et al. FASEB J. 2010 20065103 MiR-205 silences MED1 in hypoxic primary human trophoblasts.
7 Mees et al. Ann. Surg. Oncol. 2009 19475450 Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas.
8 Wang et al. J. Biol. Chem. 2008 18319255 Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target.
9 Hildebrand et al. J. Invest. Dermatol. 2011 20827281 A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo.
10 Boguslawska et al. PLoS ONE 2011 21912701 MiR-224 targets the 3'UTR of type 1 5'-iodothyronine deiodinase possibly contributing to tissue hypothyroidism in renal cancer.
11 Wang et al. PLoS ONE 2013 23922662 MicroRNA-224 targets SMAD family member 4 to promote cell proliferation and negatively influence patient survival.
12 Yao et al. Mol. Endocrinol. 2010 20118412 MicroRNA-224 is involved in transforming growth factor-beta-mediated mouse granulosa cell proliferation and granulosa cell function by targeting Smad4.
13 Liu et al. Tumour Biol. 2014 25017365 RKIP suppresses gastric cancer cell proliferation and invasion and enhances apoptosis regulated by microRNA-224.
14 Huang et al. Biochem. Biophys. Res. Commun. 2012 22809510 MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cells.
15 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
16 Olaru et al. Inflamm. Bowel Dis. 2013 23399735 MicroRNA-224 negatively regulates p21 expression during late neoplastic progression in inflammatory bowel disease.
17 Liao et al. Clin. Cancer Res. 2013 23846336 microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2.
18 Hashimoto et al. PLoS ONE 2013 23667495 Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer.
19 Li et al. J. Gastroenterol. Hepatol. 2014 24219032 miR-224 promotion of cell migration and invasion by targeting Homeobox D 10 gene in human hepatocellular carcinoma.
20 Rudnicki et al. Hum. Mol. Genet. 2014 24470395 microRNA-224 regulates Pentraxin 3, a component of the humoral arm of innate immunity, in inner ear inflammation.
21 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
22 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
23 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
24 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
25 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
26 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
27 Yuan et al. Gastroenterology 2013 23770133 Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice.
28 Goto et al. FEBS Lett. 2014 24768995 Tumour-suppressive microRNA-224 inhibits cancer cell migration and invasion via targeting oncogenic TPD52 in prostate cancer.
29 Upraity et al. Biochem. Biophys. Res. Commun. 2014 24785373 MiR-224 expression increases radiation sensitivity of glioblastoma cells.
30 Lin et al. Int. J. Cancer 2014 24382668 MicroRNA-224 inhibits progression of human prostate cancer by downregulating TRIB1.
31 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
32 Majoros et al. Nat. Methods 2013 23708386 MicroRNA target site identification by integrating sequence and binding information.
33 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
34 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
35 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
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