miRCarta - targets

hsa-miR-491-5p (MIMAT0002807) (104 targets) in miRTarBase

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hsa-miR-491-5p


qRT-PCR	[1]
GFP reporter assay	[1]
Western blot	[2] [1]
Luciferase reporter assay	[2]
Flow cytometry	[1]

hsa-miR-491-5p


qRT-PCR	[3]
microarray	[4] [3]
Western blot	[3] [4]
Luciferase reporter assay	[4]
Immunohistochemistry	[3]

hsa-miR-491-5p


qRT-PCR	[3]
microarray	[3]
Western blot	[3]
Immunohistochemistry	[3]

hsa-miR-491-5p


qRT-PCR	[1]
GFP reporter assay	[1]
Western blot	[1]
Flow cytometry	[1]
PAR-CLIP	[5]

hsa-miR-491-5p


PAR-CLIP	[6] [7] [5]

hsa-miR-491-5p


PAR-CLIP	[7]

hsa-miR-491-5p


PAR-CLIP	[7]

hsa-miR-491-5p


PAR-CLIP	[5]

hsa-miR-491-5p


PAR-CLIP	[8] [9]

hsa-miR-491-5p


PAR-CLIP	[9] [5]

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References

	authors	journal	year	Pubmed link	title
1	Guo et al.	Molecules	2012	23519249	MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway.
2	Nakano et al.	Int. J. Cancer	2010	20039318	Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells.
3	Zhou et al.	Liver Int.	2013	23725476	MicroRNA-491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition.
4	Yan et al.	Brain Res.	2011	21831363	Identification of MMP-9 specific microRNA expression profile as potential targets of anti-invasion therapy in glioblastoma multiforme.
5	Whisnant et al.	MBio	2013	23592263	In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
6	Memczak et al.	Nature	2013	23446348	Circular RNAs are a large class of animal RNAs with regulatory potency.
7	Kishore et al.	Nat. Methods	2011	21572407	A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
8	Hafner et al.	Cell	2010	20371350	Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
9	Lipchina et al.	Genes Dev.	2011	22012620	Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
10	Huang et al.	Cancer Res.	2014	24335959	miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis.
11	Jiang et al.	Toxicol. Lett.	2014	25196641	Inhibition of TGF-β/SMAD3/NF-κB signaling by microRNA-491 is involved in arsenic trioxide-induced anti-angiogenesis in hepatocellular carcinoma cells.
12	Gottwein et al.	Cell Host Microbe	2011	22100165	Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
13	Farazi et al.	Genome Biol.	2014	24398324	Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
14	Skalsky et al.	PLoS Pathog.	2012	22291592	The viral and cellular microRNA targetome in lymphoblastoid cell lines.
15	Pillai et al.	Breast Cancer Res. Treat.	2014	24906430	HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.
16	Karginov et al.	Genes Dev.	2013	23824327	Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
17	Xue et al.	Cell	2013	23313552	Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
18	Chi et al.	Nature	2009	19536157	Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.

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