Targets miRBase

hsa-miR-217 (MIMAT0000274) (62 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-217 SIRT1
qRT-PCR [1]
Western blot [2] [1]
Luciferase reporter assay [2] [1]
hsa-miR-217 ROBO1
qRT-PCR [3]
Western blot [3]
Luciferase reporter assay [3]
hsa-miR-217 PTEN
Western blot [4]
Luciferase reporter assay [4] [5]
hsa-miR-217 NR4A2
microarray [6]
Luciferase reporter assay [6]
hsa-miR-217 PPM1D
Immunoblot [7]
Luciferase reporter assay [7]
hsa-miR-217 FHIT
Luciferase reporter assay [8]
hsa-miR-217 KRAS
Reporter assay [9]
Luciferase reporter assay [9]
hsa-miR-217 SMAD7
Luciferase reporter assay [5]
hsa-miR-217 E2F3
Western blot [10]
Luciferase reporter assay [10]
Immunohistochemistry [10]
hsa-miR-217 DACH1
qRT-PCR [11]
Western blot [11]
Luciferase reporter assay [11]
hsa-miR-217 MAP1B
PAR-CLIP [12]
hsa-miR-217 TP53INP1
PAR-CLIP [13]
hsa-miR-217 LMLN
PAR-CLIP [14]
hsa-miR-217 FLVCR1
PAR-CLIP [12]
hsa-miR-217 ZNF268
PAR-CLIP [14] [12]
hsa-miR-217 FOXO3
qRT-PCR [15]
Western blot [15]
Luciferase reporter assay [15]
hsa-miR-217 GHITM
PAR-CLIP [14]
hsa-miR-217 ZNF317
PAR-CLIP [16]
hsa-miR-217 GPC5
Northern blot [17]
qRT-PCR [17]
Western blot [17]
Luciferase reporter assay [17]
hsa-miR-217 ZNF583
PAR-CLIP [18]
hsa-miR-217 SRSF11
PAR-CLIP [18]
hsa-miR-217 SNRNP27
PAR-CLIP [16]
hsa-miR-217 ACBD3
PAR-CLIP [16]
hsa-miR-217 TMEM67
PAR-CLIP [19]
hsa-miR-217 HSPA4L
PAR-CLIP [20] [13]
hsa-miR-217 TCF7L2
PAR-CLIP [14] [20]
hsa-miR-217 SFTPB
PAR-CLIP [14]
hsa-miR-217 OSBPL3
PAR-CLIP [14]
hsa-miR-217 RAB11B
PAR-CLIP [14]
hsa-miR-217 HOXA13
PAR-CLIP [21]
hsa-miR-217 TMSB4X
PAR-CLIP [21]
hsa-miR-217 TAF1D
PAR-CLIP [21]
hsa-miR-217 ADSS
PAR-CLIP [12] [20] [21]
hsa-miR-217 TNFRSF21
PAR-CLIP [20]
hsa-miR-217 HIF1A
PAR-CLIP [20]
hsa-miR-217 TMEM63A
PAR-CLIP [20]
hsa-miR-217 PNRC2
PAR-CLIP [20]
hsa-miR-217 CREBZF
PAR-CLIP [20]
hsa-miR-217 MARCH5
HITS-CLIP [22] [23] [24]
hsa-miR-217 DNAL1
HITS-CLIP [22]
hsa-miR-217 BACH2
HITS-CLIP [22]
hsa-miR-217 UBXN11
HITS-CLIP [22]
hsa-miR-217 CKAP4
HITS-CLIP [22]
hsa-miR-217 STK40
HITS-CLIP [22]
hsa-miR-217 ZBTB20
HITS-CLIP [22]
hsa-miR-217 NHLRC2
HITS-CLIP [22]
hsa-miR-217 TCERG1
HITS-CLIP [22]
hsa-miR-217 VPS8
HITS-CLIP [22]
hsa-miR-217 TACO1
HITS-CLIP [22]
hsa-miR-217 CA6
HITS-CLIP [25]
hsa-miR-217 LACTB
HITS-CLIP [24]
hsa-miR-217 MXD1
HITS-CLIP [24]
hsa-miR-217 MMGT1
HITS-CLIP [24]
hsa-miR-217 CDC73
HITS-CLIP [24]
hsa-miR-217 BTG1
HITS-CLIP [24]
hsa-miR-217 FAM196B
HITS-CLIP [26]
hsa-miR-217 WDR82P1
HITS-CLIP [26]
hsa-miR-217 SLC4A2
HITS-CLIP [26]
hsa-miR-217 ZNF490
HITS-CLIP [26]
hsa-miR-217 LSG1
HITS-CLIP [26]
hsa-miR-217 ELF5
HITS-CLIP [26]
hsa-miR-217 HINFP
HITS-CLIP [26]

References

authors journal year Pubmed link title
1 Deng et al. Cancer Lett. 2014 25172416 Chronic pancreatitis and pancreatic cancer demonstrate active epithelial-mesenchymal transition profile, regulated by miR-217-SIRT1 pathway.
2 Menghini et al. Circulation 2009 19786632 MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1.
3 Tie et al. PLoS Genet. 2010 20300657 MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor.
4 Inui et al. Nat. Rev. Mol. Cell Biol. 2010 20216554 MicroRNA control of signal transduction.
5 Xia et al. Hepatology 2013 23471579 MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer.
6 Tsai et al. J. Cell. Biochem. 2010 19885849 Identification of microRNAs regulated by activin A in human embryonic stem cells.
7 Zhang et al. Cancer Res. 2010 20668064 Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway.
8 Lin et al. Cancer Biother. Radiopharm. 2011 21711110 microRNA-143 protects cells from DNA damage-induced killing by downregulating FHIT expression.
9 Zhao et al. Carcinogenesis 2010 20675343 The miR-217 microRNA functions as a potential tumor suppressor in pancreatic ductal adenocarcinoma by targeting KRAS.
10 Su et al. Mol. Cell. Biochem. 2014 24671492 miR-217 inhibits invasion of hepatocellular carcinoma cells through direct suppression of E2F3.
11 Zhang et al. J Cancer 2015 25653720 MiR-217 Promotes Tumor Proliferation in Breast Cancer via Targeting DACH1.
12 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
13 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
14 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
15 Zhang et al. PLoS ONE 2013 24376725 MicroRNA-217 promotes angiogenesis of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and FOXO3A.
16 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
17 Wang et al. PLoS ONE 2015 26098560 The MicroRNA-217 Functions as a Potential Tumor Suppressor in Gastric Cancer by Targeting GPC5.
18 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
19 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
20 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
21 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
22 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
23 Haecker et al. PLoS Pathog. 2012 22927820 Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas.
24 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
25 Kishore et al. Genome Biol. 2013 23706177 Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing.
26 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.