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hsa-miR-205-5p (MIMAT0000266) (164 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-205-5p LRP1
qRT-PCR [1]
Western blot [1]
Luciferase reporter assay [1]
hsa-miR-205-5p ZEB1
qRT-PCR [2]
microarray [3]
ChIP [4]
LacZ reporter assay [4]
Western blot [3] [5]
Other [2]
HITS-CLIP [6]
Luciferase reporter assay [3]
hsa-miR-205-5p MED1
qRT-PCR [7]
Western blot [7] [8]
HITS-CLIP [6]
Luciferase reporter assay [8]
hsa-miR-205-5p E2F5
Reporter assay [9]
hsa-miR-205-5p E2F1
qRT-PCR [10]
Reporter assay [9]
Western blot [10] [11]
Luciferase reporter assay [10] [11]
hsa-miR-205-5p ERBB3
qRT-PCR [12] [13]
microarray [14]
Reporter assay [15]
Western blot [12] [13] [14]
Other [15]
Luciferase reporter assay [8] [15] [13] [14]
hsa-miR-205-5p ZEB2
qRT-PCR [16]
microarray [3]
ChIP [4]
LacZ reporter assay [4]
Western blot [3]
Immunoblot [16]
Luciferase reporter assay [3]
hsa-miR-205-5p PRKCE
qRT-PCR [16]
Immunoblot [16]
hsa-miR-205-5p IL24
qRT-PCR [17]
Western blot [17]
Luciferase reporter assay [18] [17]
hsa-miR-205-5p IL32
qRT-PCR [17]
Western blot [17]
Luciferase reporter assay [17]
hsa-miR-205-5p EGLN2
qRT-PCR [19]
microarray [19]
Western blot [19]
Luciferase reporter assay [19]
hsa-miR-205-5p TP73
qRT-PCR [20]
Western blot [20]
hsa-miR-205-5p CYR61
Western blot [21]
hsa-miR-205-5p CTGF
Western blot [21]
hsa-miR-205-5p ERBB2
qRT-PCR [22]
Western blot [22]
hsa-miR-205-5p LAMC1
qRT-PCR [10]
Western blot [10]
Luciferase reporter assay [10]
hsa-miR-205-5p LRRK2
qRT-PCR [23]
Western blot [23]
Luciferase reporter assay [23]
hsa-miR-205-5p YES1
Reporter assay [24]
PAR-CLIP [25]
hsa-miR-205-5p SRC
Reporter assay [24]
hsa-miR-205-5p BCL2
qRT-PCR [26]
Western blot [27] [26]
Luciferase reporter assay [27]
Immunohistochemistry [26]
hsa-miR-205-5p SMAD1
qRT-PCR [28]
Western blot [28]
Luciferase reporter assay [28]
hsa-miR-205-5p SMAD4
qRT-PCR [28]
Western blot [28]
Luciferase reporter assay [28]
hsa-miR-205-5p YY1
qRT-PCR [29]
Western blot [29]
Luciferase reporter assay [29]
hsa-miR-205-5p PTPRM
qRT-PCR [30]
microarray [30]
Luciferase reporter assay [30]
Immunohistochemistry [30]
hsa-miR-205-5p AR
qRT-PCR [31]
microarray [31]
In situ hybridization [31]
Western blot [31]
HITS-CLIP [32]
Luciferase reporter assay [31]
Immunoprecipitation [31]
hsa-miR-205-5p BCL6
Western blot [33]
Luciferase reporter assay [33]
hsa-miR-205-5p ACSL4
qRT-PCR [34]
Western blot [34]
Luciferase reporter assay [34]
hsa-miR-205-5p ITGA5
qRT-PCR [35]
Western blot [35]
Luciferase reporter assay [35]
Immunohistochemistry [35]
hsa-miR-205-5p ACSL1
qRT-PCR [36]
Western blot [36]
Luciferase reporter assay [36]
hsa-miR-205-5p STK38L
HITS-CLIP [6]
hsa-miR-205-5p NUFIP2
HITS-CLIP [6]
hsa-miR-205-5p PTPRJ
HITS-CLIP [6]
hsa-miR-205-5p XPR1
HITS-CLIP [6]
hsa-miR-205-5p ETNK1
HITS-CLIP [6]
hsa-miR-205-5p DMXL2
HITS-CLIP [6]
hsa-miR-205-5p NSF
HITS-CLIP [6]
hsa-miR-205-5p UBE2Z
HITS-CLIP [6]
hsa-miR-205-5p GNAS
HITS-CLIP [6] [37]
hsa-miR-205-5p SQLE
HITS-CLIP [6]
hsa-miR-205-5p CPEB3
HITS-CLIP [6]
hsa-miR-205-5p ETF1
PAR-CLIP [38] [39]
hsa-miR-205-5p ZNF585B
PAR-CLIP [40]
hsa-miR-205-5p HMGB3
qRT-PCR [41]
Western blot [41]
Luciferase reporter assay [41]
hsa-miR-205-5p PTEN
qRT-PCR [42] [43] [44]
ChIP [44]
Western blot [44] [42] [43]
Luciferase reporter assay [42] [44]
Immunohistochemistry [44]
ELISA [44]
hsa-miR-205-5p ESRRG
Luciferase reporter assay [45]
hsa-miR-205-5p PHLPP2
qRT-PCR [44]
ChIP [44]
Western blot [44]
Luciferase reporter assay [44]
Immunohistochemistry [44]
ELISA [44]
hsa-miR-205-5p KCNJ10
qRT-PCR [46]
Western blot [46]
Luciferase reporter assay [46]
hsa-miR-205-5p YEATS2
HITS-CLIP [6]
hsa-miR-205-5p VAMP1
HITS-CLIP [6]
hsa-miR-205-5p TOLLIP
HITS-CLIP [6]
hsa-miR-205-5p TMEM55B
HITS-CLIP [6]
hsa-miR-205-5p TMEM123
HITS-CLIP [6]
hsa-miR-205-5p TAF11
HITS-CLIP [6]
hsa-miR-205-5p SERTAD2
HITS-CLIP [6]
hsa-miR-205-5p RTN3
HITS-CLIP [6]
hsa-miR-205-5p RFX7
HITS-CLIP [6]
hsa-miR-205-5p RAP2B
HITS-CLIP [6]
hsa-miR-205-5p PLAGL2
HITS-CLIP [6]
hsa-miR-205-5p PICALM
HITS-CLIP [6]
hsa-miR-205-5p PHC2
HITS-CLIP [6]
hsa-miR-205-5p PARD6B
HITS-CLIP [6]
hsa-miR-205-5p PANK1
HITS-CLIP [6]
hsa-miR-205-5p NOTCH2
HITS-CLIP [6]
hsa-miR-205-5p NIPA2
HITS-CLIP [6]
hsa-miR-205-5p NDUFB2
HITS-CLIP [6]
hsa-miR-205-5p NDUFA4
HITS-CLIP [6]
hsa-miR-205-5p MMD
HITS-CLIP [6]
hsa-miR-205-5p MGLL
HITS-CLIP [6]
hsa-miR-205-5p MED13
HITS-CLIP [6]
hsa-miR-205-5p MARCKS
HITS-CLIP [6]
hsa-miR-205-5p LYSMD3
HITS-CLIP [6]
hsa-miR-205-5p LYN
HITS-CLIP [6]
hsa-miR-205-5p LRRC59
HITS-CLIP [6]
hsa-miR-205-5p LPCAT1
HITS-CLIP [6]
hsa-miR-205-5p IPO7
HITS-CLIP [6]
hsa-miR-205-5p SARAF
HITS-CLIP [6]
hsa-miR-205-5p EZR
HITS-CLIP [6]
hsa-miR-205-5p ENPP4
HITS-CLIP [6]
hsa-miR-205-5p CUL5
HITS-CLIP [6]
hsa-miR-205-5p CLIP1
HITS-CLIP [6]
hsa-miR-205-5p CDKN2AIPNL
HITS-CLIP [6]
hsa-miR-205-5p CDK6
HITS-CLIP [6]
hsa-miR-205-5p GUCD1
HITS-CLIP [6]
hsa-miR-205-5p C1orf123
HITS-CLIP [6]
hsa-miR-205-5p B4GALT6
HITS-CLIP [6]
hsa-miR-205-5p B4GALT5
HITS-CLIP [6]
hsa-miR-205-5p AFF4
HITS-CLIP [6]
hsa-miR-205-5p AFF1
HITS-CLIP [6]
hsa-miR-205-5p TEX35
PAR-CLIP [47]
hsa-miR-205-5p SMIM13
PAR-CLIP [39]
hsa-miR-205-5p SERINC3
PAR-CLIP [38] [48] [40] [39] [49]
hsa-miR-205-5p RNF217
HITS-CLIP [50]
PAR-CLIP [39]
hsa-miR-205-5p NFAT5
PAR-CLIP [39]
hsa-miR-205-5p LCOR
PAR-CLIP [39]
hsa-miR-205-5p NPRL3
PAR-CLIP [51]
hsa-miR-205-5p ACTRT3
PAR-CLIP [52]
hsa-miR-205-5p GOT1
PAR-CLIP [52]
hsa-miR-205-5p F2RL2
PAR-CLIP [52]
hsa-miR-205-5p DHCR24
PAR-CLIP [52]
hsa-miR-205-5p EID2B
PAR-CLIP [38]
hsa-miR-205-5p SLC38A1
PAR-CLIP [38] [40]
hsa-miR-205-5p RAB11FIP1
PAR-CLIP [40] [38]
hsa-miR-205-5p C11orf74
HITS-CLIP [40]
PAR-CLIP [38] [40]
hsa-miR-205-5p DNAJA1
PAR-CLIP [38] [48] [40]
hsa-miR-205-5p LRRTM4
PAR-CLIP [25]
hsa-miR-205-5p SLC39A14
PAR-CLIP [25]
hsa-miR-205-5p BDP1
PAR-CLIP [25]
hsa-miR-205-5p TRAF3IP1
PAR-CLIP [25]
hsa-miR-205-5p ICK
PAR-CLIP [25]
hsa-miR-205-5p PRLR
PAR-CLIP [25]
hsa-miR-205-5p BORCS5
PAR-CLIP [25]
hsa-miR-205-5p ACP1
PAR-CLIP [25]
hsa-miR-205-5p PHF12
PAR-CLIP [25]
hsa-miR-205-5p MAP3K9
HITS-CLIP [50]
PAR-CLIP [48] [25]
hsa-miR-205-5p MAML2
PAR-CLIP [25]
hsa-miR-205-5p AMOT
PAR-CLIP [40]
hsa-miR-205-5p HOXA11
PAR-CLIP [40]
hsa-miR-205-5p IMPAD1
PAR-CLIP [48]
hsa-miR-205-5p TCF20
HITS-CLIP [32]
hsa-miR-205-5p PRR15
HITS-CLIP [32]
hsa-miR-205-5p PAPPA-AS1
HITS-CLIP [32]
hsa-miR-205-5p CFAP65
HITS-CLIP [32]
hsa-miR-205-5p PRRG4
HITS-CLIP [32]
hsa-miR-205-5p BCL9L
HITS-CLIP [32]
hsa-miR-205-5p SHISA6
HITS-CLIP [32]
hsa-miR-205-5p JMJD1C
HITS-CLIP [32]
hsa-miR-205-5p SMNDC1
HITS-CLIP [32]
hsa-miR-205-5p PLCXD2
HITS-CLIP [32]
hsa-miR-205-5p ANGPTL7
HITS-CLIP [32]
hsa-miR-205-5p SRD5A1
HITS-CLIP [32]
hsa-miR-205-5p TNFSF8
HITS-CLIP [32]
hsa-miR-205-5p VPS52
HITS-CLIP [32]
hsa-miR-205-5p TMEM239
HITS-CLIP [32]
hsa-miR-205-5p SLC7A2
HITS-CLIP [32]
hsa-miR-205-5p SLC41A1
HITS-CLIP [32]
hsa-miR-205-5p RBBP4
HITS-CLIP [32]
hsa-miR-205-5p PAIP2B
HITS-CLIP [32]
hsa-miR-205-5p NOX5
HITS-CLIP [32]
hsa-miR-205-5p NEK9
HITS-CLIP [32]
hsa-miR-205-5p MRPL44
HITS-CLIP [32]
hsa-miR-205-5p SLC25A25
HITS-CLIP [32]
hsa-miR-205-5p CREB1
HITS-CLIP [32]
hsa-miR-205-5p CDK1
HITS-CLIP [37]
hsa-miR-205-5p RAN
HITS-CLIP [37]
hsa-miR-205-5p BAMBI
HITS-CLIP [37]
hsa-miR-205-5p KCTD16
HITS-CLIP [50]
hsa-miR-205-5p TMSB4X
HITS-CLIP [50]
hsa-miR-205-5p GM2A
HITS-CLIP [50]
hsa-miR-205-5p TMEM201
HITS-CLIP [50]
hsa-miR-205-5p PHF8
HITS-CLIP [50]
hsa-miR-205-5p TM9SF2
HITS-CLIP [50]
hsa-miR-205-5p YWHAH
HITS-CLIP [50]
hsa-miR-205-5p SPDL1
HITS-CLIP [50]
hsa-miR-205-5p MAPK14
HITS-CLIP [50]
hsa-miR-205-5p TXNL1
HITS-CLIP [50]
hsa-miR-205-5p RGS6
HITS-CLIP [50]
hsa-miR-205-5p KCTD20
HITS-CLIP [50]
hsa-miR-205-5p XPOT
HITS-CLIP [50]
hsa-miR-205-5p SLC5A12
HITS-CLIP [50]
hsa-miR-205-5p VTI1A
HITS-CLIP [50]
hsa-miR-205-5p C6orf201
HITS-CLIP [50]
hsa-miR-205-5p NUDT21
HITS-CLIP [50]
hsa-miR-205-5p KLHL5
HITS-CLIP [50]
hsa-miR-205-5p NCAPG
HITS-CLIP [50]

References

authors journal year Pubmed link title
1 Song et al. Biochem. Biophys. Res. Commun. 2009 19665999 MicroRNA-205 inhibits tumor cell migration through down-regulating the expression of the LDL receptor-related protein 1.
2 Hurteau et al. Cell Cycle 2009 19502803 Stable expression of miR-200c alone is sufficient to regulate TCF8 (ZEB1) and restore E-cadherin expression.
3 Gregory et al. Nat. Cell Biol. 2008 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.
4 Lee et al. Oncogene 2014 23474752 Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer.
5 Gandellini et al. Cell Death Differ. 2012 22555458 miR-205 regulates basement membrane deposition in human prostate: implications for cancer development.
6 Riley et al. EMBO J. 2012 22473208 EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency.
7 Hulf et al. Oncogene 2013 22869146 Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer.
8 Mouillet et al. FASEB J. 2010 20065103 MiR-205 silences MED1 in hypoxic primary human trophoblasts.
9 Dar et al. J. Biol. Chem. 2011 21454583 miRNA-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1 protein.
10 Piovan et al. Mol Oncol 2012 22578566 Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer.
11 Noguchi et al. Mol. Ther. 2013 23629002 Chemically modified synthetic microRNA-205 inhibits the growth of melanoma cells in vitro and in vivo.
12 Wang et al. Cell Death Dis 2013 23519125 Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells.
13 Iorio et al. Cancer Res. 2009 19276373 microRNA-205 regulates HER3 in human breast cancer.
14 Barker et al. Curr Opin Pharmacol 2010 20864407 Regulation of ErbB receptor signalling in cancer cells by microRNA.
15 Wu et al. Cell Res. 2009 19238171 Suppression of cell growth and invasion by miR-205 in breast cancer.
16 Gandellini et al. Cancer Res. 2009 19244118 miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.
17 Majid et al. Cancer 2010 20737563 MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer.
18 Kim et al. Mol. Cells 2013 23212344 MicroRNA-205 directly regulates the tumor suppressor, interleukin-24, in human KB oral cancer cells.
19 Muratsu-Ikeda et al. PLoS ONE 2012 22859986 Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells.
20 Alla et al. Cell Cycle 2012 22871739 E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry.
21 Xie et al. PLoS ONE 2012 23056551 miR-205 expression promotes cell proliferation and migration of human cervical cancer cells.
22 Adachi et al. Biochem. Biophys. Res. Commun. 2011 21787752 ErbB2 down-regulates microRNA-205 in breast cancer.
23 Cho et al. Hum. Mol. Genet. 2013 23125283 MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein.
24 Majid et al. Cancer Res. 2011 21330408 MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer.
25 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
26 Tian et al. Med. Oncol. 2014 24297308 MicroRNA-205 suppresses proliferation and promotes apoptosis in laryngeal squamous cell carcinoma.
27 Verdoodt et al. Int. J. Oncol. 2013 23612742 MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer.
28 Tabruyn et al. Angiogenesis 2013 23800974 MiR-205 is downregulated in hereditary hemorrhagic telangiectasia and impairs TGF-beta signaling pathways in endothelial cells.
29 Yin et al. Eur Rev Med Pharmacol Sci 2014 24763883 Down-regulation of microRNA-205 promotes gastric cancer cell proliferation.
30 Luo et al. J Transl Med 2013 23497265 A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells.
31 Hagman et al. Br. J. Cancer 2013 23571738 miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients.
32 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
33 Motsch et al. PLoS ONE 2012 22870299 MicroRNA profiling of Epstein-Barr virus-associated NK/T-cell lymphomas by deep sequencing.
34 Cui et al. Biochem. Biophys. Res. Commun. 2014 24576478 Involvement of cholesterol in hepatitis B virus X protein-induced abnormal lipid metabolism of hepatoma cells via up-regulating miR-205-targeted ACSL4.
35 Larzabal et al. Br. J. Cancer 2014 24434435 TMPRSS4 regulates levels of integrin α5 in NSCLC through miR-205 activity to promote metastasis.
36 Cui et al. Biochem. Biophys. Res. Commun. 2014 24462768 MiR-205 modulates abnormal lipid metabolism of hepatoma cells via targeting acyl-CoA synthetase long-chain family member 1 (ACSL1) mRNA.
37 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
38 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
39 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
40 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
41 Elgamal et al. PLoS ONE 2013 24098490 Tumor suppressive function of mir-205 in breast cancer is linked to HMGB3 regulation.
42 Lei et al. Oncol. Rep. 2013 24084898 miR-205 promotes the growth, metastasis and chemoresistance of NSCLC cells by targeting PTEN.
43 Wang et al. Oncol. Rep. 2013 23564023 SZ-685C exhibits potent anticancer activity in both radiosensitive and radioresistant NPC cells through the miR-205-PTEN-Akt pathway.
44 Cai et al. Cancer Res. 2013 23856247 miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer.
45 Su et al. Oncol. Rep. 2013 23589079 miR-205 promotes tumor proliferation and invasion through targeting ESRRG in endometrial carcinoma.
46 Lin et al. Invest. Ophthalmol. Vis. Sci. 2013 23950153 Inhibition of miR-205 impairs the wound-healing process in human corneal epithelial cells by targeting KIR4.1 (KCNJ10).
47 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
48 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
49 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
50 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
51 Majoros et al. Nat. Methods 2013 23708386 MicroRNA target site identification by integrating sequence and binding information.
52 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
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