Targets miRBase

hsa-miR-205-5p (MIMAT0000266) (164 targets) in miRTarBase

References

authors journal year Pubmed link title
1 Song et al. Biochem. Biophys. Res. Commun. 2009 19665999 MicroRNA-205 inhibits tumor cell migration through down-regulating the expression of the LDL receptor-related protein 1.
2 Hurteau et al. Cell Cycle 2009 19502803 Stable expression of miR-200c alone is sufficient to regulate TCF8 (ZEB1) and restore E-cadherin expression.
3 Gregory et al. Nat. Cell Biol. 2008 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.
4 Lee et al. Oncogene 2014 23474752 Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer.
5 Gandellini et al. Cell Death Differ. 2012 22555458 miR-205 regulates basement membrane deposition in human prostate: implications for cancer development.
6 Riley et al. EMBO J. 2012 22473208 EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency.
7 Hulf et al. Oncogene 2013 22869146 Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer.
8 Mouillet et al. FASEB J. 2010 20065103 MiR-205 silences MED1 in hypoxic primary human trophoblasts.
9 Dar et al. J. Biol. Chem. 2011 21454583 miRNA-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1 protein.
10 Piovan et al. Mol Oncol 2012 22578566 Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer.
11 Noguchi et al. Mol. Ther. 2013 23629002 Chemically modified synthetic microRNA-205 inhibits the growth of melanoma cells in vitro and in vivo.
12 Iorio et al. Cancer Res. 2009 19276373 microRNA-205 regulates HER3 in human breast cancer.
13 Wang et al. Cell Death Dis 2013 23519125 Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells.
14 Barker et al. Curr Opin Pharmacol 2010 20864407 Regulation of ErbB receptor signalling in cancer cells by microRNA.
15 Wu et al. Cell Res. 2009 19238171 Suppression of cell growth and invasion by miR-205 in breast cancer.
16 Gandellini et al. Cancer Res. 2009 19244118 miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.
17 Majid et al. Cancer 2010 20737563 MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer.
18 Kim et al. Mol. Cells 2013 23212344 MicroRNA-205 directly regulates the tumor suppressor, interleukin-24, in human KB oral cancer cells.
19 Muratsu-Ikeda et al. PLoS ONE 2012 22859986 Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells.
20 Alla et al. Cell Cycle 2012 22871739 E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry.
21 Xie et al. PLoS ONE 2012 23056551 miR-205 expression promotes cell proliferation and migration of human cervical cancer cells.
22 Adachi et al. Biochem. Biophys. Res. Commun. 2011 21787752 ErbB2 down-regulates microRNA-205 in breast cancer.
23 Cho et al. Hum. Mol. Genet. 2013 23125283 MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein.
24 Majid et al. Cancer Res. 2011 21330408 MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer.
25 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
26 Tian et al. Med. Oncol. 2014 24297308 MicroRNA-205 suppresses proliferation and promotes apoptosis in laryngeal squamous cell carcinoma.
27 Verdoodt et al. Int. J. Oncol. 2013 23612742 MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer.
28 Tabruyn et al. Angiogenesis 2013 23800974 MiR-205 is downregulated in hereditary hemorrhagic telangiectasia and impairs TGF-beta signaling pathways in endothelial cells.
29 Yin et al. Eur Rev Med Pharmacol Sci 2014 24763883 Down-regulation of microRNA-205 promotes gastric cancer cell proliferation.
30 Luo et al. J Transl Med 2013 23497265 A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells.
31 Hagman et al. Br. J. Cancer 2013 23571738 miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients.
32 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
33 Motsch et al. PLoS ONE 2012 22870299 MicroRNA profiling of Epstein-Barr virus-associated NK/T-cell lymphomas by deep sequencing.
34 Cui et al. Biochem. Biophys. Res. Commun. 2014 24576478 Involvement of cholesterol in hepatitis B virus X protein-induced abnormal lipid metabolism of hepatoma cells via up-regulating miR-205-targeted ACSL4.
35 Larzabal et al. Br. J. Cancer 2014 24434435 TMPRSS4 regulates levels of integrin α5 in NSCLC through miR-205 activity to promote metastasis.
36 Cui et al. Biochem. Biophys. Res. Commun. 2014 24462768 MiR-205 modulates abnormal lipid metabolism of hepatoma cells via targeting acyl-CoA synthetase long-chain family member 1 (ACSL1) mRNA.
37 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
38 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
39 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
40 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
41 Elgamal et al. PLoS ONE 2013 24098490 Tumor suppressive function of mir-205 in breast cancer is linked to HMGB3 regulation.
42 Cai et al. Cancer Res. 2013 23856247 miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer.
43 Lei et al. Oncol. Rep. 2013 24084898 miR-205 promotes the growth, metastasis and chemoresistance of NSCLC cells by targeting PTEN.
44 Wang et al. Oncol. Rep. 2013 23564023 SZ-685C exhibits potent anticancer activity in both radiosensitive and radioresistant NPC cells through the miR-205-PTEN-Akt pathway.
45 Su et al. Oncol. Rep. 2013 23589079 miR-205 promotes tumor proliferation and invasion through targeting ESRRG in endometrial carcinoma.
46 Lin et al. Invest. Ophthalmol. Vis. Sci. 2013 23950153 Inhibition of miR-205 impairs the wound-healing process in human corneal epithelial cells by targeting KIR4.1 (KCNJ10).
47 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
48 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
49 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
50 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
51 Majoros et al. Nat. Methods 2013 23708386 MicroRNA target site identification by integrating sequence and binding information.
52 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
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