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hsa-miR-181b-5p (MIMAT0000257) (350 targets) in miRTarBase

References

authors journal year Pubmed link title
1 Ji et al. Hepatology 2009 19585654 Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells.
2 Guo et al. Asian Pac. J. Cancer Prev. 2012 22901205 miR-181b as a potential molecular target for anticancer therapy of gastric neoplasms.
3 Wang et al. Oncogene 2010 20023698 TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3.
4 Lu et al. J. Biol. Chem. 2011 22009755 Anti-microRNA-222 (anti-miR-222) and -181B suppress growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal.
5 Pallasch et al. Blood 2009 19692702 miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.
6 Beveridge et al. Hum. Mol. Genet. 2008 18184693 Dysregulation of miRNA 181b in the temporal cortex in schizophrenia.
7 Cai et al. Oncol. Rep. 2013 23440261 miRNA-181b increases the sensitivity of pancreatic ductal adenocarcinoma cells to gemcitabine in vitro and in nude mice by targeting BCL-2.
8 Zhu et al. Int. J. Cancer 2010 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines.
9 Zhu et al. Carcinogenesis 2012 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes.
10 Pichiorri et al. Proc. Natl. Acad. Sci. U.S.A. 2008 18728182 MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis.
11 Pekarsky et al. Cancer Res. 2006 17178851 Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181.
12 Chen et al. Sci China Life Sci 2010 20596961 microRNA-181b targets MLK2 in HL-60 cells.
13 Iliopoulos et al. Mol. Cell 2010 20797623 STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer.
14 Cao et al. Cancer Cell 2011 21840484 Coordinated regulation of polycomb group complexes through microRNAs in cancer.
15 Wang et al. Biochem. Biophys. Res. Commun. 2012 22446332 miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients.
16 Rivetti di Val Cervo et al. Proc. Natl. Acad. Sci. U.S.A. 2012 22228303 p63-microRNA feedback in keratinocyte senescence.
17 Mansueto et al. Genes Cancer 2010 21779448 Identification of a New Pathway for Tumor Progression: MicroRNA-181b Up-Regulation and CBX7 Down-Regulation by HMGA1 Protein.
18 Shi et al. RNA 2013 23431408 MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas.
19 Carroll et al. BMC Genomics 2012 23083446 Alternative mRNA fates identified in microRNA-associated transcriptome analysis.
20 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
21 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
22 Riley et al. EMBO J. 2012 22473208 EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency.
23 Xia et al. Biochem. Biophys. Res. Commun. 2014 24735543 MicroRNA-181b promotes ovarian cancer cell growth and invasion by targeting LATS2.
24 Li et al. Blood 2012 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.
25 Bisso et al. Cell Cycle 2013 23656790 Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer.
26 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
27 Chen et al. IUBMB Life 2012 22539488 MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas.
28 She et al. Med. Oncol. 2014 24573637 miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeleton remodeling in glioblastoma cells.
29 Yang et al. FEBS Lett. 2014 24269684 miR-181b promotes cell proliferation and reduces apoptosis by repressing the expression of adenylyl cyclase 9 (AC9) in cervical cancer cells.
30 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
31 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
32 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
33 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
34 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
35 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
36 Wang et al. Cancer Chemother. Pharmacol. 2013 23645289 miR-181b modulates glioma cell sensitivity to temozolomide by targeting MEK1.
37 Tao et al. Eur. J. Cancer 2013 23810250 Involvement of FOS-mediated miR-181b/miR-21 signalling in the progression of malignant gliomas.
38 McClure et al. Infect. Immun. 2014 24980967 MicroRNA 21 (miR-21) and miR-181b couple with NFI-A to generate myeloid-derived suppressor cells and promote immunosuppression in late sepsis.
39 lyu et al. Biochem. Biophys. Res. Commun. 2013 24055707 MiR-181b targets Six2 and inhibits the proliferation of metanephric mesenchymal cells in vitro.
40 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
41 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
42 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
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