miRCarta - targets

hsa-miR-10b-5p (MIMAT0000254) (292 targets) in miRTarBase

Copy CSV Excel Column visibility Reset

Showing 1 to 10 of 292 entries

Search:

miRNA

gene name

experiments

hsa-miR-10b-5p

HOXD10


qRT-PCR	[1] [2]
In situ hybridization	[2]
Reporter assay	[3] [4]
Western blot	[5] [3] [6] [7] [1] [2]
Immunocytochemistry	[7]
Luciferase reporter assay	[3] [8] [7] [6] [1] [2]
Immunohistochemistry	[2] [9]
3'LIFE	[10]

hsa-miR-10b-5p

KLF4


qRT-PCR	[1] [11]
Western blot	[1] [12] [11]
Luciferase reporter assay	[1] [12]
Flow cytometry	[11]

hsa-miR-10b-5p

PPARA


qRT-PCR	[13]
Western blot	[13]
Luciferase reporter assay	[13]

hsa-miR-10b-5p

NCOR2


qRT-PCR	[14]
Western blot	[14]
3'LIFE	[10]

hsa-miR-10b-5p

NF1


qRT-PCR	[15]
microarray	[15]
GFP reporter assay	[15]
Luciferase reporter assay	[15]

hsa-miR-10b-5p

PIEZO1


Luciferase reporter assay	[16]

hsa-miR-10b-5p

BCL2L11


Western blot	[17]
HITS-CLIP	[18]
Luciferase reporter assay	[17]
PAR-CLIP	[19] [18]

hsa-miR-10b-5p

TFAP2C


Western blot	[17]
Luciferase reporter assay	[17]
PAR-CLIP	[18]

hsa-miR-10b-5p

CDKN2A


Western blot	[17]
Luciferase reporter assay	[17]
CLASH	[20]

hsa-miR-10b-5p

CDKN1A


Western blot	[17]
Luciferase reporter assay	[17]

Show entries

References

	authors	journal	year	Pubmed link	title
1	Xiao et al.	Oncol. Rep.	2014	24573354	MicroRNA-10b promotes migration and invasion through KLF4 and HOXD10 in human bladder cancer.
2	Liu et al.	Int. J. Oncol.	2012	22293682	miR-10b promotes cell invasion through RhoC-AKT signaling pathway by targeting HOXD10 in gastric cancer.
3	Ma et al.	Nature	2007	17898713	Tumour invasion and metastasis initiated by microRNA-10b in breast cancer.
4	Shen et al.	J. Biol. Chem.	2011	21642433	Heparin impairs angiogenesis through inhibition of microRNA-10b.
5	Dong et al.	Int. J. Oncol.	2012	22766763	Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells.
6	Sun et al.	Brain Res.	2011	21419107	MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10.
7	Yu et al.	PLoS ONE	2013	24376640	MicroRNA-10b promotes nucleus pulposus cell proliferation through RhoC-Akt pathway by targeting HOXD10 in intervetebral disc degeneration.
8	Lin et al.	Cell Death Dis	2012	23034333	MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme.
9	Parrella et al.	Mol. Cancer	2014	24897960	Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients.
10	Wolter et al.	Nucleic Acids Res.	2014	25074381	3'LIFE: a functional assay to detect miRNA targets in high-throughput.
11	Liu et al.	Eur. J. Med. Res.	2013	24216130	MicroRNA-10b overexpression promotes non-small cell lung cancer cell proliferation and invasion.
12	Tian et al.	J. Biol. Chem.	2010	20075075	MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines.
13	Zheng et al.	J. Gastroenterol. Hepatol.	2010	19780876	Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD.
14	Foley et al.	Cell Death Differ.	2011	21212796	MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2.
15	Chai et al.	Cancer Sci.	2010	20550523	MicroRNA-10b regulates tumorigenesis in neurofibromatosis type 1.
16	Nishida et al.	Ann. Surg. Oncol.	2012	22322955	MicroRNA-10b is a prognostic indicator in colorectal cancer and confers resistance to the chemotherapeutic agent 5-fluorouracil in colorectal cancer cells.
17	Gabriely et al.	Cancer Res.	2011	21471404	Human glioma growth is controlled by microRNA-10b.
18	Kishore et al.	Nat. Methods	2011	21572407	A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
19	Hafner et al.	Cell	2010	20371350	Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
20	Helwak et al.	Cell	2013	23622248	Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
21	Meseguer et al.	J. Biol. Chem.	2011	21118818	MicroRNAs-10a and -10b contribute to retinoic acid-induced differentiation of neuroblastoma cells and target the alternative splicing regulatory factor SFRS1 (SF2/ASF).
22	Kim et al.	Epigenetics	2011	21562367	Epigenetic regulation of microRNA-10b and targeting of oncogenic MAPRE1 in gastric cancer.
23	Ibrahim et al.	Int. J. Cancer	2012	22573479	Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism.
24	Schneider et al.	Fertil. Steril.	2013	23206733	Targeting of syndecan-1 by micro-ribonucleic acid miR-10b modulates invasiveness of endometriotic cells via dysregulation of the proteolytic milieu and interleukin-6 secretion.
25	Lipchina et al.	Genes Dev.	2011	22012620	Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
26	Li et al.	Gastric Cancer	2015	24481854	DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer.
27	Mussnich et al.	Mol Oncol	2013	23384558	The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression.
28	Liu et al.	Mol Med Rep	2013	24100613	TGF-β-induced miR10a/b expression promotes human glioma cell migration by targeting PTEN.
29	Memczak et al.	Nature	2013	23446348	Circular RNAs are a large class of animal RNAs with regulatory potency.
30	Ouyang et al.	Oncogene	2014	24096486	microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actions.
31	Dong et al.	Biochem. Biophys. Res. Commun.	2014	25312779	Reduction of TIP30 in esophageal squamous cell carcinoma cells involves promoter methylation and microRNA-10b.
32	Karginov et al.	Genes Dev.	2013	23824327	Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
33	Gottwein et al.	Cell Host Microbe	2011	22100165	Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
34	Whisnant et al.	MBio	2013	23592263	In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
35	Farazi et al.	Genome Biol.	2014	24398324	Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
36	Skalsky et al.	PLoS Pathog.	2012	22291592	The viral and cellular microRNA targetome in lymphoblastoid cell lines.
37	Chi et al.	Nature	2009	19536157	Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
38	Xue et al.	Cell	2013	23313552	Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
39	Pillai et al.	Breast Cancer Res. Treat.	2014	24906430	HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.
40	Kishore et al.	Genome Biol.	2013	23706177	Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing.

Targets miRBase

hsa-miR-10b-5p (MIMAT0000254) (292 targets) in miRTarBase

References