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hsa-miR-148a-3p (MIMAT0000243) (187 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-148a-3p DNMT1
qRT-PCR [1] [2] [3]
Western blot [1] [2] [3]
Luciferase reporter assay [4] [3] [5]
Flow cytometry [1]
hsa-miR-148a-3p HLA-G
Luciferase reporter assay [6]
hsa-miR-148a-3p TGIF2
Western blot [7]
Luciferase reporter assay [7]
hsa-miR-148a-3p DNMT3B
qRT-PCR [8] [9]
microarray [9]
GFP reporter assay [8]
Western blot [8]
hsa-miR-148a-3p NR1I2
qRT-PCR [10]
Luciferase reporter assay [10]
hsa-miR-148a-3p RPS6KA5
qRT-PCR [11]
Reporter assay [11]
Western blot [11]
Luciferase reporter assay [11]
hsa-miR-148a-3p CCKBR
qRT-PCR [12] [13]
microarray [14]
Western blot [12] [13]
Luciferase reporter assay [14] [12]
hsa-miR-148a-3p IRS1
Western blot [15]
Luciferase reporter assay [15]
hsa-miR-148a-3p ACVR1
Luciferase reporter assay [16]
hsa-miR-148a-3p BCL2
Luciferase reporter assay [17]
hsa-miR-148a-3p TMED7
Luciferase reporter assay [18]
hsa-miR-148a-3p GPATCH8
Sequencing [19]
hsa-miR-148a-3p TMEM14A
Sequencing [19]
hsa-miR-148a-3p ANP32A
Sequencing [19]
hsa-miR-148a-3p RAB1B
Sequencing [19]
hsa-miR-148a-3p HSP90B1
Sequencing [19]
hsa-miR-148a-3p POFUT1
Sequencing [19]
hsa-miR-148a-3p CYCS
Sequencing [19]
hsa-miR-148a-3p ADARB1
Sequencing [19]
hsa-miR-148a-3p CBX3
Sequencing [19]
hsa-miR-148a-3p UQCRQ
Sequencing [19]
hsa-miR-148a-3p SPRY2
Sequencing [19]
hsa-miR-148a-3p PAN3
Sequencing [19]
hsa-miR-148a-3p KANSL1
Sequencing [19]
hsa-miR-148a-3p GAS1
Sequencing [19]
PAR-CLIP [20] [19] [21]
hsa-miR-148a-3p PTPN4
Sequencing [19]
hsa-miR-148a-3p ZNF92
Sequencing [19]
hsa-miR-148a-3p RAB10
Sequencing [19]
hsa-miR-148a-3p PAPD4
Sequencing [19]
PAR-CLIP [21]
hsa-miR-148a-3p HCCS
Sequencing [19]
hsa-miR-148a-3p WAPL
Sequencing [19]
hsa-miR-148a-3p MPP5
Sequencing [19]
hsa-miR-148a-3p ZNF490
Sequencing [19]
hsa-miR-148a-3p RAB12
Sequencing [19]
PAR-CLIP [21]
hsa-miR-148a-3p GNB5
Sequencing [19]
hsa-miR-148a-3p SNAPIN
Sequencing [19]
PAR-CLIP [22]
hsa-miR-148a-3p PSMD9
Sequencing [19]
hsa-miR-148a-3p TRIM59
Sequencing [19]
hsa-miR-148a-3p DYNLL2
Sequencing [19]
hsa-miR-148a-3p SECISBP2L
Sequencing [19]
PAR-CLIP [19] [21] [22]
hsa-miR-148a-3p LYSMD1
Sequencing [19]
hsa-miR-148a-3p PBXIP1
Luciferase reporter assay [23]
Sequencing [19]
hsa-miR-148a-3p MTMR9
Sequencing [19]
hsa-miR-148a-3p DNAJB4
Sequencing [19]
hsa-miR-148a-3p DSTYK
Sequencing [19]
hsa-miR-148a-3p LBR
Sequencing [19]
hsa-miR-148a-3p KIAA1549
Sequencing [19]
hsa-miR-148a-3p DYRK1A
Sequencing [19]
hsa-miR-148a-3p CDK19
Sequencing [19]
PAR-CLIP [24]
hsa-miR-148a-3p RAB34
Sequencing [19]
PAR-CLIP [21]
hsa-miR-148a-3p ARRDC3
Sequencing [19]
hsa-miR-148a-3p PRNP
Sequencing [19]
hsa-miR-148a-3p HOXC8
Sequencing [19]
hsa-miR-148a-3p TMEM9B
Sequencing [19]
hsa-miR-148a-3p RASSF8
Sequencing [19]
hsa-miR-148a-3p BTBD3
HITS-CLIP [21]
Sequencing [19]
PAR-CLIP [20] [19] [21] [25] [22] [26]
hsa-miR-148a-3p TNRC6A
Sequencing [19]
PAR-CLIP [25]
hsa-miR-148a-3p SESTD1
Sequencing [19]
hsa-miR-148a-3p CDC25B
Reporter assay [27]
Western blot [27]
Other [27]
hsa-miR-148a-3p MRPL45
CLASH [28]
hsa-miR-148a-3p DENR
CLASH [28]
hsa-miR-148a-3p APPBP2
CLASH [28]
hsa-miR-148a-3p SLC2A3
CLASH [28]
hsa-miR-148a-3p PTPN23
CLASH [28]
hsa-miR-148a-3p VPS41
CLASH [28]
hsa-miR-148a-3p MSL3
CLASH [28]
hsa-miR-148a-3p AMELX
CLASH [28]
hsa-miR-148a-3p OR2C3
CLASH [28]
hsa-miR-148a-3p SLC25A3
CLASH [28]
hsa-miR-148a-3p APC
CLASH [28]
hsa-miR-148a-3p GOLIM4
CLASH [28]
hsa-miR-148a-3p MYCBP2
CLASH [28]
hsa-miR-148a-3p RPS17
CLASH [28]
hsa-miR-148a-3p HSPA4
CLASH [28]
hsa-miR-148a-3p WDTC1
CLASH [28]
hsa-miR-148a-3p HMGB1
CLASH [28]
hsa-miR-148a-3p MAP3K4
CLASH [28]
hsa-miR-148a-3p USP38
CLASH [28]
hsa-miR-148a-3p NONO
CLASH [28]
hsa-miR-148a-3p CCNI
CLASH [28]
hsa-miR-148a-3p AURKB
CLASH [28]
hsa-miR-148a-3p MMP7
qRT-PCR [29]
microarray [29]
In situ hybridization [29]
Western blot [29]
Luciferase reporter assay [29]
hsa-miR-148a-3p WNT10B
qRT-PCR [30]
microarray [30]
Western blot [30]
Luciferase reporter assay [30]
hsa-miR-148a-3p MYC
qRT-PCR [31]
microarray [31]
Immunoblot [31]
hsa-miR-148a-3p CDKN1B
Northern blot [18]
In situ hybridization [18]
Western blot [18]
Luciferase reporter assay [18]
PAR-CLIP [21] [22]
hsa-miR-148a-3p SERPINE1
qRT-PCR [32]
microarray [32]
Luciferase reporter assay [32]
hsa-miR-148a-3p ITGB8
qRT-PCR [32]
microarray [32]
Luciferase reporter assay [32]
PAR-CLIP [22]
hsa-miR-148a-3p VAV2
qRT-PCR [32]
microarray [32]
Luciferase reporter assay [32]
hsa-miR-148a-3p ITGA5
qRT-PCR [32]
microarray [32]
Luciferase reporter assay [32]
hsa-miR-148a-3p ROCK1
qRT-PCR [33]
Western blot [33]
Luciferase reporter assay [33] [34]
Immunohistochemistry [33]
hsa-miR-148a-3p RUNX3
qRT-PCR [35]
Western blot [35]
hsa-miR-148a-3p SMAD2
qRT-PCR [36]
Western blot [36]
Luciferase reporter assay [36]
hsa-miR-148a-3p UNKL
microarray [37]
hsa-miR-148a-3p MET
qRT-PCR [38]
Immunofluorescence [38]
Western blot [38]
Immunoblot [38]
Luciferase reporter assay [38]
Immunohistochemistry [38]
hsa-miR-148a-3p CEP55
PAR-CLIP [19] [21]
hsa-miR-148a-3p MLEC
PAR-CLIP [19] [21]
hsa-miR-148a-3p BCL2L11
qRT-PCR [39]
Immunoblot [39]
Luciferase reporter assay [39]
hsa-miR-148a-3p VPS37A
PAR-CLIP [21]
hsa-miR-148a-3p TXNIP
PAR-CLIP [20] [26]
hsa-miR-148a-3p KIF2C
PAR-CLIP [22]
hsa-miR-148a-3p ARID3A
PAR-CLIP [22]
hsa-miR-148a-3p SIK1
PAR-CLIP [20] [21] [22]
hsa-miR-148a-3p ARL8B
PAR-CLIP [22]
hsa-miR-148a-3p HLA-A
PAR-CLIP [22]
hsa-miR-148a-3p CCT6A
PAR-CLIP [21]
hsa-miR-148a-3p GPRC5A
PAR-CLIP [22]
hsa-miR-148a-3p GLRX5
PAR-CLIP [21]
hsa-miR-148a-3p STX16
PAR-CLIP [22]
hsa-miR-148a-3p TNRC6B
PAR-CLIP [22]
hsa-miR-148a-3p CEBPG
PAR-CLIP [19]
hsa-miR-148a-3p SH3PXD2A
PAR-CLIP [22]
hsa-miR-148a-3p RBM38
PAR-CLIP [22]
hsa-miR-148a-3p MAFB
Luciferase reporter assay [40]
hsa-miR-148a-3p ERRFI1
qRT-PCR [39]
Immunoblot [39]
Luciferase reporter assay [39]
hsa-miR-148a-3p S1PR1
qRT-PCR [41]
Western blot [41]
Luciferase reporter assay [41]
Immunohistochemistry [41]
hsa-miR-148a-3p USP4
qRT-PCR [41]
Western blot [41]
Luciferase reporter assay [41]
Immunohistochemistry [41]
hsa-miR-148a-3p CNOT4
PAR-CLIP [19] [21] [22]
hsa-miR-148a-3p ZDHHC6
PAR-CLIP [22]
hsa-miR-148a-3p TTLL1
PAR-CLIP [22]
hsa-miR-148a-3p POC1A
PAR-CLIP [22]
hsa-miR-148a-3p MRPS27
PAR-CLIP [22]
hsa-miR-148a-3p B4GALT7
PAR-CLIP [22]
hsa-miR-148a-3p ZIC5
PAR-CLIP [22]
hsa-miR-148a-3p WASL
PAR-CLIP [22]
hsa-miR-148a-3p STX6
PAR-CLIP [22]
hsa-miR-148a-3p SLC38A2
PAR-CLIP [21] [22]
hsa-miR-148a-3p RPS6KA4
PAR-CLIP [22]
hsa-miR-148a-3p RCC2
PAR-CLIP [22]
hsa-miR-148a-3p RAB14
PAR-CLIP [22]
hsa-miR-148a-3p PPP6R1
PAR-CLIP [22]
hsa-miR-148a-3p MAP3K9
PAR-CLIP [22]
hsa-miR-148a-3p EOGT
PAR-CLIP [21] [22]
hsa-miR-148a-3p DDX6
PAR-CLIP [22]
hsa-miR-148a-3p CCNA2
PAR-CLIP [19] [21] [22]
hsa-miR-148a-3p ZFYVE26
PAR-CLIP [25] [22]
hsa-miR-148a-3p KLF6
PAR-CLIP [22]
hsa-miR-148a-3p DICER1
PAR-CLIP [21] [22]
hsa-miR-148a-3p HLA-C
PAR-CLIP [22]
hsa-miR-148a-3p ETV7
PAR-CLIP [22]
hsa-miR-148a-3p PATL1
PAR-CLIP [22]
hsa-miR-148a-3p PDIK1L
PAR-CLIP [42]
hsa-miR-148a-3p SLC12A7
PAR-CLIP [42]
hsa-miR-148a-3p STARD13
PAR-CLIP [19] [26]
hsa-miR-148a-3p AGO2
PAR-CLIP [26] [21]
hsa-miR-148a-3p YWHAB
PAR-CLIP [20]
hsa-miR-148a-3p UBE2D3
PAR-CLIP [20]
hsa-miR-148a-3p LNPEP
PAR-CLIP [20] [19]
hsa-miR-148a-3p RFT1
PAR-CLIP [20]
hsa-miR-148a-3p VPS37B
PAR-CLIP [20]
hsa-miR-148a-3p KPNA4
HITS-CLIP [21]
PAR-CLIP [20]
hsa-miR-148a-3p RBM23
PAR-CLIP [25]
hsa-miR-148a-3p AKAP17A
PAR-CLIP [25]
hsa-miR-148a-3p MYO3A
PAR-CLIP [25]
hsa-miR-148a-3p FZD5
PAR-CLIP [25]
hsa-miR-148a-3p HSP90AA1
PAR-CLIP [21]
hsa-miR-148a-3p NDRG1
PAR-CLIP [21]
hsa-miR-148a-3p BMP3
PAR-CLIP [21]
hsa-miR-148a-3p BAZ2B
PAR-CLIP [21]
hsa-miR-148a-3p ASB6
PAR-CLIP [21]
hsa-miR-148a-3p AGO3
PAR-CLIP [21]
hsa-miR-148a-3p RNF219
PAR-CLIP [19]
hsa-miR-148a-3p NPTX1
PAR-CLIP [19]
hsa-miR-148a-3p SESN3
PAR-CLIP [19]
hsa-miR-148a-3p OTUD4
PAR-CLIP [19]
hsa-miR-148a-3p IGFBP5
PAR-CLIP [19]
hsa-miR-148a-3p DCUN1D3
PAR-CLIP [19]
hsa-miR-148a-3p FAM104A
PAR-CLIP [19]
hsa-miR-148a-3p WNT2B
HITS-CLIP [43] [44]
hsa-miR-148a-3p FOXP1
HITS-CLIP [44]
hsa-miR-148a-3p COLEC12
HITS-CLIP [44]
hsa-miR-148a-3p AP5B1
HITS-CLIP [44]
hsa-miR-148a-3p PHACTR2
HITS-CLIP [44]
hsa-miR-148a-3p PLPP4
HITS-CLIP [44]
hsa-miR-148a-3p ABLIM1
HITS-CLIP [44]
hsa-miR-148a-3p SORD
HITS-CLIP [44]
hsa-miR-148a-3p PLA2G12A
HITS-CLIP [44]
hsa-miR-148a-3p IL23R
HITS-CLIP [44]
hsa-miR-148a-3p CHRFAM7A
HITS-CLIP [44]
hsa-miR-148a-3p SOS2
HITS-CLIP [44]
hsa-miR-148a-3p S1PR2
HITS-CLIP [44]
hsa-miR-148a-3p KIAA0907
HITS-CLIP [45] [21]
hsa-miR-148a-3p VGLL2
HITS-CLIP [45]
hsa-miR-148a-3p JARID2
HITS-CLIP [45]
hsa-miR-148a-3p DTX4
HITS-CLIP [43]
hsa-miR-148a-3p FAM212B
HITS-CLIP [43]
hsa-miR-148a-3p YPEL1
HITS-CLIP [43]
hsa-miR-148a-3p OVOL1
HITS-CLIP [43]

References

authors journal year Pubmed link title
1 Zhu et al. Med. Oncol. 2012 22167392 MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer.
2 Yan et al. Med. Oncol. 2014 24515776 MiR-148a regulates MEG3 in gastric cancer by targeting DNA methyltransferase 1.
3 Pan et al. J. Immunol. 2010 20483747 MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1.
4 Long et al. Int. J. Oncol. 2014 24714841 MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in hepatocellular carcinogenesis.
5 Braconi et al. Hepatology 2010 20146264 MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes.
6 Tan et al. Am. J. Hum. Genet. 2007 17847008 Allele-specific targeting of microRNAs to HLA-G and risk of asthma.
7 Lujambio et al. Proc. Natl. Acad. Sci. U.S.A. 2008 18768788 A microRNA DNA methylation signature for human cancer metastasis.
8 Duursma et al. RNA 2008 18367714 miR-148 targets human DNMT3b protein coding region.
9 Merkerova et al. Stem Cells Dev. 2010 19435428 MicroRNA expression profiles in umbilical cord blood cell lineages.
10 Takagi et al. J. Biol. Chem. 2008 18268015 Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.
11 Fujita et al. J. Biol. Chem. 2010 20406806 MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression.
12 Zhang et al. Tumour Biol. 2014 23975374 MiR-148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl-2.
13 Chen et al. J. Gastrointest. Surg. 2010 20422307 Altered expression of MiR-148a and MiR-152 in gastrointestinal cancers and its clinical significance.
14 Muiños-Gimeno et al. Biol. Psychiatry 2011 21168126 Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways.
15 Xu et al. J Mol Cell Biol 2013 22935141 A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1.
16 Song et al. Int J Mol Sci 2012 22408438 ACVR1, a therapeutic target of fibrodysplasia ossificans progressiva, is negatively regulated by miR-148a.
17 Zhang et al. Cell Death Differ. 2011 21455217 MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer.
18 Guo et al. Int. J. Biol. Sci. 2011 21552422 miR-148a promoted cell proliferation by targeting p27 in gastric cancer cells.
19 Hafner et al. Cell 2010 20371350 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
20 Memczak et al. Nature 2013 23446348 Circular RNAs are a large class of animal RNAs with regulatory potency.
21 Kishore et al. Nat. Methods 2011 21572407 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins.
22 Whisnant et al. MBio 2013 23592263 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.
23 Xu et al. J. Clin. Invest. 2013 23321675 Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
24 Gottwein et al. Cell Host Microbe 2011 22100165 Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
25 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
26 Farazi et al. Genome Biol. 2014 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
27 Liffers et al. Lab. Invest. 2011 21709669 MicroRNA-148a is down-regulated in human pancreatic ductal adenocarcinomas and regulates cell survival by targeting CDC25B.
28 Helwak et al. Cell 2013 23622248 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding.
29 Sakamoto et al. Cancer Sci. 2014 24283384 MicroRNA-148a is downregulated in gastric cancer, targets MMP7, and indicates tumor invasiveness and poor prognosis.
30 Aprelikova et al. Oncogene 2013 22890324 Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility.
31 Han et al. Hepatology 2013 23389829 A c-Myc-MicroRNA functional feedback loop affects hepatocarcinogenesis.
32 Tseng et al. BMC Syst Biol 2011 21703006 Integrative network analysis reveals active microRNAs and their functions in gastric cancer.
33 Zheng et al. Clin. Cancer Res. 2011 21994419 MicroRNA-148a suppresses tumor cell invasion and metastasis by downregulating ROCK1 in gastric cancer.
34 Li et al. Mol. Cell. Biochem. 2013 23670799 MicroRNA-148a suppresses epithelial-to-mesenchymal transition by targeting ROCK1 in non-small cell lung cancer cells.
35 Zuo et al. Mol. Cells 2013 23549984 MicroRNA-148a can regulate runt-related transcription factor 3 gene expression via modulation of DNA methyltransferase 1 in gastric cancer.
36 Wang et al. Tumour Biol. 2013 23873106 microRNA-148a suppresses human gastric cancer cell metastasis by reversing epithelial-to-mesenchymal transition.
37 Lee et al. Biochem. Biophys. Res. Commun. 2012 22995316 Molecular signatures in response to Isoliquiritigenin in lymphoblastoid cell lines.
38 Zhang et al. Oncogene 2014 24013226 MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling.
39 Kim et al. Cancer Res. 2014 24425048 microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma.
40 Cheng et al. J. Bone Miner. Res. 2013 23225151 miR-148a regulates osteoclastogenesis by targeting V-maf musculoaponeurotic fibrosarcoma oncogene homolog B.
41 Heo et al. Oncotarget 2014 24798342 microRNA-148a dysregulation discriminates poor prognosis of hepatocellular carcinoma in association with USP4 overexpression.
42 Skalsky et al. PLoS Pathog. 2012 22291592 The viral and cellular microRNA targetome in lymphoblastoid cell lines.
43 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
44 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
45 Xue et al. Cell 2013 23313552 Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
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