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hsa-miR-451a (MIMAT0001631) (23 targets) in miRTarBase

miRNA gene name experiments
hsa-miR-451a MIF
qRT-PCR [1]
microarray [1]
Western blot [1] [2]
Luciferase reporter assay [1] [2]
ELISA [1]
hsa-miR-451a CAB39
Northern blot [3]
qRT-PCR [4] [5] [3]
microarray [5]
In situ hybridization [4] [3]
Western blot [4] [3] [5]
Immunocytochemistry [3]
Luciferase reporter assay [4] [5]
hsa-miR-451a ABCB1
qRT-PCR [6]
Western blot [6]
Luciferase reporter assay [6]
hsa-miR-451a AKT1
qRT-PCR [7]
Western blot [7]
hsa-miR-451a MMP2
qRT-PCR [7]
Western blot [7]
hsa-miR-451a MMP9
qRT-PCR [7]
Western blot [7]
hsa-miR-451a BCL2
qRT-PCR [7]
Western blot [7]
hsa-miR-451a MYC
Luciferase reporter assay [8] [9]
hsa-miR-451a RAB14
qRT-PCR [10]
microarray [10]
Reporter assay [10]
Western blot [10]
Luciferase reporter assay [10]
Flow cytometry [10]
hsa-miR-451a TMED7
qRT-PCR [7]
Western blot [7]
hsa-miR-451a ARPP19
microarray [11]
hsa-miR-451a UBE2H
microarray [11]
hsa-miR-451a CPNE3
qRT-PCR [12] [13]
Western blot [12] [13]
Luciferase reporter assay [12] [13]
Flow cytometry [13]
hsa-miR-451a RAB5A
qRT-PCR [13] [12]
Western blot [13] [12]
Luciferase reporter assay [13] [12]
Flow cytometry [13]
hsa-miR-451a DCBLD2
qRT-PCR [14]
Western blot [14]
Luciferase reporter assay [14]
hsa-miR-451a IL6R
qRT-PCR [15]
Western blot [15]
HITS-CLIP [16]
hsa-miR-451a IKBKB
Luciferase reporter assay [17]
hsa-miR-451a FRZB
qRT-PCR [18]
hsa-miR-451a OSR1
qRT-PCR [18]
hsa-miR-451a PKD1
qRT-PCR [18]
hsa-miR-451a ROR2
qRT-PCR [18]
hsa-miR-451a CUX2
PAR-CLIP [19]
hsa-miR-451a SZRD1
HITS-CLIP [20]

References

authors journal year Pubmed link title
1 Bandres et al. Clin. Cancer Res. 2009 19318487 microRNA-451 regulates macrophage migration inhibitory factor production and proliferation of gastrointestinal cancer cells.
2 Liu et al. Mol. Cancer 2013 24138931 MiR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma.
3 Chen et al. PLoS ONE 2012 22844503 Micro-RNA-195 and -451 regulate the LKB1/AMPK signaling axis by targeting MO25.
4 Tian et al. Int. J. Oncol. 2012 22179124 MicroRNA miR-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma.
5 Godlewski et al. Mol. Cell 2010 20227367 MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells.
6 Kovalchuk et al. Mol. Cancer Ther. 2008 18645025 Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.
7 Nan et al. Brain Res. 2010 20816946 MiRNA-451 plays a role as tumor suppressor in human glioma cells.
8 Chen et al. Eur. J. Cancer 2014 25310895 MicroRNA-451 induces epithelial-mesenchymal transition in docetaxel-resistant lung adenocarcinoma cells by targeting proto-oncogene c-Myc.
9 Li et al. J. Exp. Med. 2011 21464222 Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL.
10 Wang et al. Oncogene 2011 21358675 MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14).
11 Bruchova-Votavova et al. Leuk. Lymphoma 2010 20218812 miR-451 enhances erythroid differentiation in K562 cells.
12 et al. None 24249046
13 Murata et al. Arthritis Rheumatol. 2014 24574214 MicroRNA-451 down-regulates neutrophil chemotaxis via p38 MAPK.
14 Fukumoto et al. Br. J. Cancer 2014 24918822 Identification of tumour suppressive microRNA-451a in hypopharyngeal squamous cell carcinoma based on microRNA expression signature.
15 Liu et al. Cancer Epidemiol 2014 24445140 MicroRNA-451 suppresses tumor cell growth by down-regulating IL6R gene expression.
16 Chi et al. Nature 2009 19536157 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.
17 Li et al. Carcinogenesis 2013 23740840 miR-451 inhibits cell proliferation in human hepatocellular carcinoma through direct suppression of IKK-β.
18 Li et al. Int. J. Pediatr. Otorhinolaryngol. 2013 23294929 MicroRNA expression profiling and target genes study in congenital microtia.
19 Lipchina et al. Genes Dev. 2011 22012620 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
20 Karginov et al. Genes Dev. 2013 23824327 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
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