Targets miRBase

cel-let-7-5p (MIMAT0000001) (30 targets) in miRTarBase

miRNA gene name experiments
cel-let-7-5p pha-4
GFP reporter assay [1]
Reporter assay [1]
LacZ reporter assay [1]
Other [1]
cel-let-7-5p daf-12
GFP reporter assay [1]
Reporter assay [1]
LacZ reporter assay [1]
Other [1]
HITS-CLIP [2]
cel-let-7-5p die-1
GFP reporter assay [1]
Reporter assay [1]
LacZ reporter assay [1]
Other [1]
cel-let-7-5p lin-41
GFP reporter assay [3] [4] [5]
Reporter assay [3]
LacZ reporter assay [4] [6]
Other [3]
HITS-CLIP [2]
cel-let-7-5p hbl-1
GFP reporter assay [7] [8] [9]
HITS-CLIP [2]
Immunocytochemistry [8]
cel-let-7-5p let-60
GFP reporter assay [10]
Reporter assay [10]
LacZ reporter assay [10]
Other [10]
cel-let-7-5p let-526
GFP reporter assay [1]
LacZ reporter assay [1]
cel-let-7-5p prmt-1
Sequencing [11]
cel-let-7-5p K02E10.7
Sequencing [11]
cel-let-7-5p R04F11.2
Sequencing [11]
cel-let-7-5p nkb-3
Sequencing [11]
cel-let-7-5p C15H9.9
Sequencing [11]
cel-let-7-5p ZK131.11
Sequencing [11]
cel-let-7-5p atgl-1
Sequencing [11]
cel-let-7-5p F01G4.6
Sequencing [11]
cel-let-7-5p lsy-22
Sequencing [11]
cel-let-7-5p K04F10.3
Sequencing [11]
cel-let-7-5p F21C10.3
Sequencing [11]
cel-let-7-5p Y54G2A.26
Sequencing [11]
cel-let-7-5p lpr-5
Sequencing [11]
cel-let-7-5p got-2.2
Sequencing [11]
cel-let-7-5p ZK470.2
Sequencing [11]
cel-let-7-5p ZC190.4
Sequencing [11]
cel-let-7-5p mct-6
Sequencing [11]
cel-let-7-5p F57G12.1
Sequencing [11]
cel-let-7-5p B0336.3
Sequencing [11]
cel-let-7-5p mab-31
Sequencing [11]
cel-let-7-5p T27D12.1
qRT-PCR [12]
microarray [12]
Immunoprecipitaion [12]
cel-let-7-5p T14B1.1
HITS-CLIP [2]
cel-let-7-5p lin-28
HITS-CLIP [2]

References

authors journal year Pubmed link title
1 Grosshans et al. Dev. Cell 2005 15737928 The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans.
2 Grosswendt et al. Mol. Cell 2014 24857550 Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.
3 Reinhart et al. Nature 2000 10706289 The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans.
4 Slack et al. Mol. Cell 2000 10882102 The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor.
5 Zou et al. Science 2013 23599497 Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers.
6 Vella et al. Genes Dev. 2004 14729570 The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR.
7 Lin et al. Dev. Cell 2003 12737800 The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target.
8 Abrahante et al. Dev. Cell 2003 12737799 The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs.
9 Bethke et al. Science 2009 19342589 Nuclear hormone receptor regulation of microRNAs controls developmental progression.
10 Johnson et al. Cell 2005 15766527 RAS is regulated by the let-7 microRNA family.
11 Zisoulis et al. Nat. Struct. Mol. Biol. 2010 20062054 Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans.
12 Hunter et al. PLoS Genet. 2013 23516374 Functional genomic analysis of the let-7 regulatory network in Caenorhabditis elegans.