Precursor miRBase

hsa-let-7c (MI0000064)

Accession MI0000064
Name hsa-let-7c
similar to following miRCarta precursors hsa-37-324.1
potential naming conflicts with hsa-let-7c-5p (MIMAT0000064)
Organism Homo sapiens
Genome GRCh38.p10
Location chr21:16,539,828-16,539,911 (+)
miRNA hsa-let-7c-5p
miRNA hsa-let-7c-3p
Sequence (5' -> 3')
(84 nts)
GCAUCCGGGUUGAGGUAGUAGGUUGUAUGGUUUAGAGUUACACCCUGGGAGUUAACUGUACAACCUUCUAGCUUUCCUUGGAGC
MFE -31.40 kcal/mol
first miRBase version 1.1
last miRBase version 21.0
Clusters (10 kb)
(2 precursors)
hsa-mir-99a
hsa-let-7c
Family let-7 (MIPF0000002)
Experiments
experiment Pubmed link
Illumina 23034410
External DBs
Gene symbol MIRLET7C
NCBI Gene 406885

External tools

Links
HMDD

Predicted Structure

References

Authors Journal Year Pubmed link Title
1 Lagos-Quintana et al. Science 2001 11679670 Identification of novel genes coding for small expressed RNAs.
2 Michael et al. Mol. Cancer Res. 2003 14573789 Reduced accumulation of specific microRNAs in colorectal neoplasia.
3 Lui et al. Cancer Res. 2007 17616659 Patterns of known and novel small RNAs in human cervical cancer.
4 Landgraf et al. Cell 2007 17604727 A mammalian microRNA expression atlas based on small RNA library sequencing.
5 Koh et al. BMC Genomics 2010 20158877 Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of hepatic nuclear factor 4 alpha.
6 Meunier et al. Genome Res. 2013 23034410 Birth and expression evolution of mammalian microRNA genes.